Results 231 to 240 of about 391,382 (299)

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Symbiotic Germination Technique of an Endangered Epiphytic Orchid Dendrobium sinominutiflorum: A Promising Conservation Application 濒危附生兰科植物勐海石斛 (Dendrobium sinominutiflorum) 的共生萌发技术:一种具有应用前景的保护策略

Integrative Conservation, EarlyView.
We developed an effective ex‐situ conservation approach for an endangered orchid species, Dendrobium sinominutiflorum. A compatible fungal strain Tulasnella sp. was obtained by using in‐situ seed baiting technique. The Symbiotic germination with Tulasnella sp. significantly promotes seed germination and seedling growth.
Han‐Xiao Huang, Lu Tang, Xiang‐Wan Yu, Yin‐Ling Luo, Peng Chen, Yun‐Hong Tan, Yan Luo   +6 more
wiley   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Transforming Agricultural Water Management Through the Water–Energy–Food Nexus: Trends, Opportunities, Barriers and Solutions

Irrigation and Drainage, EarlyView.
ABSTRACT Agricultural water management (AWM) is increasingly transitioning towards transformative thinking, where interconnected sectors, including water, energy and food, are managed holistically. Trends point towards cross‐sectoral and harmonised strategies to optimise water use efficiency and productivity, integrate renewable energy, promote ...
Luxon Nhamo, Cuthbert Taguta, Sylvester Mpandeli, Tinashe Dirwai, Stanley Liphadzi, Tafadzwanashe Mabhaudhi   +5 more
wiley   +1 more source

Assessing the Impact of a Positive Psychology School‐Based Psychoeducation on the Mental Health of Adolescents Affected by the 2023 Earthquake in Türkiye

Journal of Adolescence, EarlyView.
ABSTRACT Introduction The purpose of this study is to examine the effectiveness and acceptability of a positive psychology‐based psychoeducation program on the psychological states, future expectations, and coping styles of adolescents affected by the 2023 earthquake in Türkiye. Methods A single‐group, pretest‐posttest design was adopted.
Veysel Kaplan, Mehmet Emin Düken, Abanoub Riad, Muhammad Alkasaby   +3 more
wiley   +1 more source

Drugs for treating infections caused by non-tubercular mycobacteria: a narrative review from the study group on mycobacteria of the Italian Society of Infectious Diseases and Tropical Medicine. [PDF]

Infection
Calcagno A, Coppola N, Sarmati L, Tadolini M, Parrella R, Matteelli A, Riccardi N, Trezzi M, Di Biagio A, Pirriatore V, Russo A, Gualano G, Pontali E, Surace L, Falbo E, Mencarini J, Palmieri F, Gori A, Schiuma M, Lapadula G, Goletti D, Study Group on Mycobacteria (MYGRO) of the Italian Society of Infectious Diseases and Tropical Medicine (SIMIT)..   +21 more
europepmc   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source