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Tropical spastic paraparesis

Handbook of Clinical Neurology, 2023
A large number of causative agents can result in spinal cord disorders in the tropics including etiologies similar to those of temperate regions such as trauma, spinal bone and disc lesions, tumors, epidural abscess, and congenital malformations. Yet infectious and nutritional disorders differ in their higher prevalence in tropical regions including ...
G. Román
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Tropical spastic paraparesis in colombia

Annals of Neurology, 1988
A high-incidence focus of tropical spastic paraparesis (TSP) occurs on the South Pacific coast of Colombia. Of 55 patients studied, 52 (94.5%) had IgG antibodies to the human T-cell lymphotropic virus type I (HTLV-I) in serum and/or cerebrospinal fluid. Control groups did not show similar high positivity.
Vladimir Zaninovic   +11 more
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The Neurourology of Tropical Spastic Paraparesis

British Journal of Urology, 1991
Summary— We report the clinical features, urodynamic results and neurophysiological findings in 6 patients with urinary symptoms related to tropical spastic paraplegia. The widespread nature of the pathological changes within the nervous system result in a complex variety of urodynamic and neurophysiological ...
I, Eardley   +4 more
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Immunological studies in tropical spastic paraparesis

Annals of Neurology, 1990
AbstractTropical spastic paraparesis (TSP) and other chronic‐progressive myelopathies have been clearly associated with increased serum and cerebrospinal fluid antibody titers to human T‐lymphotropic virus type I (HTLV‐I). However, little is known about the cellular immune function in TSP. In the present study, activated T lymphocytes were found in the
S, Jacobson   +4 more
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Tropical spastic paraparesis in an Aborigine

Medical Journal of Australia, 1993
To present the first documented case of human T-lymphotropic virus type I (HTLV-I) associated myelopathy/tropical spastic paraparesis in the Australian population.A 31-year-old Aboriginal man with an 18-month history of progressive weakness of the legs was found to have an upper motor neurone weakness of all limbs associated with sphincteric ...
N, Rajabalendaran   +5 more
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Use of cerebrospinal fluid CXCL10 and neopterin as biomarkers in HTLV-1-associated myelopathy/tropical spastic paraparesis treated with steroids

Journal of Neurology Neurosurgery & Psychiatry, 2019
Human T-cell leukaemia virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) damages the spinal cord by chronic inflammation and causes progressive lower limb motor disability.1 Because the associated symptoms gradually ...
J. Yamauchi   +11 more
semanticscholar   +1 more source

Curcumin increased the expression of c‐FLIP in HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients

Journal of Cellular Biochemistry, 2019
Human T‐cell lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) disease is a chronic neuroinflammatory disease, which is associated with HTLV‐1 infection.
Z. Poursina   +6 more
semanticscholar   +1 more source

The neuroepidemiology of tropical spastic paraparesis

Annals of Neurology, 1988
Recent neuroepidemiological studies of endemic tropical spastic paraparesis (TSP) have confirmed the existence of high-prevalence foci in several tropical islands, including Jamaica and Martinique in the Caribbean, Tumaco off the Pacific coast of Colombia, and the Seychelles in the Indian Ocean.
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Delusional disorder in tropical spastic paraparesis

Irish Journal of Psychological Medicine, 1994
AbstractA case of delusional disorder in a patient with the demyelinating disease tropical spastic paraparesis is presented. Only one similar case has previously been described. The implications are discussed.
Ahmed Mahmood   +5 more
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