Results 21 to 30 of about 635,290 (190)

Cerebrospinal Fluid From Patients With HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) With Rapid Evolution Affects Mitochondrial DNA Transcription and Network Organization in Human Glioblastoma Cells. [PDF]

J Med Virol
ABSTRACT Human T‐lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive neurodegenerative disease affecting motor and sensory functions. While alterations in cerebrospinal fluid (CSF) have been used to identify disease biomarkers, the effects of such modified CSF on CNS cells remain unexplored.
Gomes YCP, Bongers A, Jeannin P, Vicente ACP, Gessain A, Afonso PV, Espindola OM.   +6 more
europepmc   +2 more sources

Early-Onset HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis. [PDF]

Pathogens, 2020
Background: Vertical transmission of HTLV-1 could lead to the early development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). This significantly affects quality of life and increases morbimortality.
Schwalb A, Pérez-Muto V, Cachay R, Tipismana M, Álvarez C, Mejía F, González-Lagos E, Gotuzzo E.   +7 more
europepmc   +2 more sources

Balance assessment in HTLV-1 associated myelopathy or tropical spastic paraparesis. [PDF]

Rev Soc Bras Med Trop, 2020
INTRODUCTION: A good rating of the device in people with HTLV-1 in this population is essential for accuracy in prescribing data (walking). Thus, this study aimed to analyze the counterpart assessment methods that are best suited to patients with human T-
Patrício NA, Rios MA, Barbosa PC, Ribeiro JR, Vidal DG, Sá KN, Baptista AF.   +6 more
europepmc   +2 more sources

Paraparesia espástica tropical uma redefinição necessária Tropical spastic paraparesis: a necessary re-definition [PDF]

Arquivos de Neuro-Psiquiatria, 1996
O autor disserta sobre a definição de Paraparesia Espástica Tropical desde suas primeiras descrições até o envolvimento etiológico do HTLV-1 em parte dos casos.
Carlos Maurício de Castro-Costa
doaj   +2 more sources

HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Overlapping Ossification of the Ligamentum Flavum

Indian Journal of Neurosurgery, 2020
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an important cause of nontraumatic and noncompressive chronic myelopathy which generally has no improvement regardless of treatment.
Guilherme Gago, Luidia Varrone Giacomini, Frederico de Lima Gibbon, Euripedes Gomes de Carvalho Neto, Fernando Kowacs, Nelson Pires Ferreira   +5 more
doaj   +2 more sources

Urodynamic findings and vibegron effects on neurogenic lower urinary tract dysfunction caused by human T-cell leukemia virus type I-associated myelopathy/tropical spastic paraparesis. [PDF]

IJU Case Rep
Introduction Human T‐cell lymphotropic virus type 1 infection can cause HTLV‐1‐associated myelopathy/tropical spastic paraparesis, characterized by spastic paralysis of both lower limbs. More than 90% of HAM/TSP patients show lower urinary tract symptoms
Kumekawa T, Akaihata H, Natsuya H, Harigane Y, Imai H, Matsuoka K, Tanji R, Hata J, Ogawa S, Kojima Y.   +9 more
europepmc   +2 more sources

Human T-Lymphotropic Virus-1-Associated Myelopathy/Tropical Spastic Paraparesis Is Associated With Sexual Dysfunction in Infected Women of Reproductive Age. [PDF]

Sex Med, 2018
Introduction: Human T-lymphotropic virus (HTLV)-1–associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neurological disorder that mostly affects women.
Lopes Martins AL, Rios Grassi MF, de Aquino Firmino A, Lacerda Araujo JP, Paixao TS, Galvão-Castro B, Boa-Sorte N.   +6 more
europepmc   +2 more sources

Probable HTLV-I/II Tropical Spastic Paraparesis Patient from Ethiopia: A Case Report. [PDF]

Ethiop J Health Sci, 2022
BACKGROUND: Available data on the burden of Human T-cell lymphotropic virus type I/II infection for eastern Africa, limited to Ethiopia, Mozambique, and Rwanda, show prevalence lower than elsewhere in Africa (0% – 1.8%).
Melka D, Zebenigus M.
europepmc   +2 more sources

Upregulation of hsa-miR-125b in HTLV-1 asymptomatic carriers and HTLV-1-associated myelopathy/tropical spastic paraparesis patients [PDF]

Memorias do Instituto Oswaldo Cruz, 2012
The retrovirus human T lymphotropic virus type 1 (HTLV-1) promotes spastic paraparesis, adult T cell leukaemia and other diseases. Recently, some human microRNAs (miRNAs) have been described as important factors in host-virus interactions.
Larissa Deadame de Figueiredo Nicolete, Roberto Nicolete, Rodrigo Haddad, Rochele Azevedo, Fabíola Attié de Castro, Yuetsu Tanaka, Osvaldo Massaiti Takayanagui, Dimas Tadeu Covas, Simone Kashima   +8 more
doaj   +4 more sources

Neuroimmunology of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis. [PDF]

Front Microbiol, 2019
Human T-lymphotropic virus type 1 (HTLV-1) is the etiologic agent of both adult T-cell leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Nozuma S, Jacobson S.
europepmc   +2 more sources