Results 101 to 110 of about 1,200 (250)

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Molecular characterization of the A52 murine hepatocellular carcinoma cell line

Animal Models and Experimental Medicine, EarlyView.
Hepatocellular carcinoma (HCC) is a poor outcome cancer with limited therapeutic choices. To advance therapeutic development we genetically characterized the A52 murine HCC cell line. We noted genetic changes that match a subset of human HCC and this offers the opportunity to test novel targeted therapies in syngeneic mice.
Rhys Gillman, Eun Jin Sun, Miriam Wankell, Matt A. Field, Ulf Schmitz, Lionel Hebbard   +5 more
wiley   +1 more source

Pharmacological evaluation of Adenostemma lavenia acetone extract in Swiss Albino mice: Analgesic, anti‐inflammatory, and thrombolytic insights from in vivo, in vitro, density functional theory, and molecular docking studies

Animal Models and Experimental Medicine, EarlyView.
Adenostemma lavenia, a traditionally used medicinal plant, has been employed to manage pain, inflammation, and circulatory issues. This study investigates the analgesic, anti‐inflammatory, and thrombolytic potentials of the acetone extract of A. lavenia leaves (AEAL) using in vivo, in vitro, and in silico methods.
Nusrat Jahan Moon, Mahathir Mohammad, Md. Jahirul Islam Mamun, Fahmina Binty Azim Nova, Nazmul Hasan Eshaque, Md. Hossain Rasel, Zobayed Islam, Md. Mahmudul Hasan, Md. Liakot Ali, Md. Tanvir Chowdhury, S. M. Moazzem Hossen   +10 more
wiley   +1 more source

Exploring biotechnological and functional characteristics of probiotic yeasts: A review. [PDF]

Biotechnol Rep (Amst), 2022
Shruthi B, Deepa N, Somashekaraiah R, Adithi G, Divyashree S, Sreenivasa MY.   +5 more
europepmc   +1 more source

Promenade architecturale [PDF]

, 2011
A San Paolo del Brasile, lo studio fotografico SC è disegnato da Marcio Kogan come una performance in cui si passa dalla geometria alla ...
ROCCA, ALESSANDRO
core  

Chronic alcohol consumption compromises gut barrier integrity and promotes endotoxemia: Implications for sepsis susceptibility in immunocompromised hosts

Animal Models and Experimental Medicine, EarlyView.
Chronic alcohol exposure disrupts intestinal barrier integrity, resulting in a leaky gut and enhanced translocation of lipopolysaccharide (LPS) and microbial products into the systemic circulation. Alcohol‐induced endotoxemia drives exaggerated pro‐inflammatory responses, mitochondrial damage, and activation of the cGAS–STING pathway, particularly in ...
Thansita Bhunyakarnjanarat, Chatsuree Suksamai, Dhammika Leshan Wannigama, Kent Doi, Wiwat Chancharoenthana, Asada Leelahavanichkul   +5 more
wiley   +1 more source

Production Country Origin Impact on Soybean Oil Quality

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Previous studies have suggested variability in soybean oil quality depending on geographic origin of the soybeans. In this study, 1035 crude degummed soybean oil (raw oil unrefined except for degumming) samples collected from vessels and crushers over five harvest years (2020–2024) were analyzed for 11 key quality attributes.
Huazhen Liu, Micah Pope, Todd Doehring, Pradeep Kachroo, David Hildebrand   +4 more
wiley   +1 more source

Democracia nos trópicos: contribuições do movimento tropicalista para a democracia no Brasil

Revista Interdisciplinar em Cultura e Sociedade, 2019
Os anos de 1960 representaram, talvez, o momento de maior aproximação do país com qualquer possibilidade de mudança no seu quadro político e social. Movimentos culturais, sindicais e populares se espalharam por diversos Estados, estimulando debates sobre
FILIPPE DE OLIVEIRA MOTA, ISADORA DESTERRO E SILVA XAVIER   +1 more
doaj  

Highly contiguous assemblies of 101 drosophilid genomes. [PDF]

Elife, 2021
Kim BY, Wang JR, Miller DE, Barmina O, Delaney E, Thompson A, Comeault AA, Peede D, D'Agostino ERR, Pelaez J, Aguilar JM, Haji D, Matsunaga T, Armstrong EE, Zych M, Ogawa Y, Stamenković-Radak M, Jelić M, Veselinović MS, Tanasković M, Erić P, Gao JJ, Katoh TK, Toda MJ, Watabe H, Watada M, Davis JS, Moyle LC, Manoli G, Bertolini E, Košťál V, Hawley RS, Takahashi A, Jones CD, Price DK, Whiteman N, Kopp A, Matute DR, Petrov DA.   +38 more
europepmc   +1 more source

SLIPPERY discourses of intertwined crises: migration and Covid-19 pandemic in a postcolonial nation [PDF]

The outbreak of a pandemic inevitably links with migration as containment measures usually involve the closure of borders. In the Portuguese context, mediated discourses of these intertwined crises were varied and multifaceted, reflecting the country’s ...
Minga, Ester
core   +1 more source