Copper-Heparin Inhalation Therapy To Repair Emphysema: A Scientific Rationale
International Journal of COPD, 2019 Rob Janssen,1 Emiel FM Wouters,2 Wim Janssens,3 Willeke F Daamen,4 Paul Hagedoorn,5 Hugo AJM de Wit,6 Jef Serré,3 Ghislaine Gayan-Ramirez,3 Frits ME Franssen,2 Niki L Reynaert,2 Jan H von der Thüsen,7 Henderik W Frijlink5 1Department of ...
Janssen R +11 more
doaj
Measurement of MMP-9 and -12 degraded elastin (ELM) provides unique information on lung tissue degradation [PDF]
, 2012 BACKGROUND: Elastin is an essential component of selected connective tissues that provides a unique physiological elasticity. Elastin may be considered a signature protein of lungs where matrix metalloprotease (MMP) -9-and -12, may be considered the ...
Arkadiusz Nawrocki +12 more
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Developmental regulation of tropoelastin isoforms.
Journal of Biological Chemistry, 1988 The production of tropoelastin isoforms was examined by cell-free translation of nuchal ligament RNA from cows of various ages ranging from 110 days of gestation to adult. Tropoelastin polypeptides synthesized in vitro were immunoprecipitated with a specific monoclonal antibody and separated by high resolution sodium dodecyl sulfate-polyacrylamide gel ...
W C, Parks +3 more
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Changes in the physical structure and chain dynamics of elastin network in homocysteine-cultured arteries [PDF]
, 2009 The thermal and dielectric properties of the elastin network were investigated in arteries cultured with physiological and pathological concentrations of homocysteine, an aminoacid responsible of histological impairments in human arteries.
Chareyre, Corinne +6 more
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Pathogenesis of chronic obstructive pulmonary disease [PDF]
, 2005 The current paradigm for the pathogenesis of chronic obstructive pulmonary disease is that chronic airflow limitation results from an abnormal inflammatory response to inhaled particles and gases in the lung. Airspace inflammation appears to be different
Macnee, W
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A Novel Cell Adhesion Region in Tropoelastin Mediates Attachment to Integrin αVβ5 [PDF]
, 2013 Pearl Lee +3 more
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Insights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners [PDF]
, 2018 Lysyl oxidase (LOX) catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagens and elastin, which is the first step of the cross-linking of these extracellular matrix proteins.
Duclos, Bertrand +6 more
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Imaging Tropoelastin in Atherosclerosis [PDF]
Circulation: Cardiovascular Imaging, 2018 Duivenvoorden, Raphaël +1 more
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Biomimetic Mineralization of Recombinamer-Based Hydrogels toward Controlled Morphologies and High Mineral Density [PDF]
, 2015 Producción CientíficaThe use of insoluble organic matrices as a structural template for the bottom-up fabrication of organic−inorganic nanocomposites is a powerful way to build a variety of advanced materials with defined and controlled morphologies and ...
Aparicio, Conrado +4 more
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A cell-based assay for CD63-containing extracellular vesicles [PDF]
, 2019 Extracellular vesicles (EVs) are thought to be important in cell-cell communication and have elicited extraordinary interest as potential biomarkers of disease. However, quantitative methods to enable elucidation of mechanisms underlying release are few.
Cashikar, Anil G, Hanson, Phyllis I
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