Results 241 to 250 of about 9,068 (269)

Tropoelastin Expression by Periodontal Fibroblasts

Journal of Dental Research, 2002
Elastic system fibers are load-bearing proteins found in periodontal tissue. There are three types—oxytalan, elaunin, and elastic fibers—which differ in their relative microfibril and elastin contents. Oxytalan fibers are known to be distributed in the periodontal ligaments and gingiva, whereas elaunin and elastic fibers are present only in the ...
E, Tsuruga, K, Irie, Y, Sakakura, T, Yajima   +3 more
openaire   +2 more sources

The evolutionary background and functional consequences of the rs2071307 polymorphism in human tropoelastin

Biopolymers, 2020
Elastin is a major polymeric protein of the extracellular matrix, providing critical properties of extensibility and elastic recoil. The rs2071307 genomic polymorphism, resulting in the substitution of a serine for a glycine residue in a VPG motif in ...
Sean E. Reichheld, Lisa D. Muiznieks, Q. Huynh, Nick Wang, Christopher E. Ing, Ming Miao, E. Sitarz, R. Pomès, S. Sharpe, F. Keeley   +9 more
semanticscholar   +1 more source

Primary Structure of Porcine Tropoelastin

1977
Structural studies on porcine aortic tropoelastin as obtained from copper-deficient swine have been performed on the whole protein as well as fragments produced by trypsin, subtilisin and thrombin digestion. Tryptic fragments fall into two catagories, those large, over 20 residues, and those small, 4 residues and less.
L B, Sandberg, W R, Gray, J A, Foster, A R, Torres, V L, Alvarez, J, Janata   +5 more
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Biosynthesis of Tropoelastin by Elastic Cartilage

Connective Tissue Research, 1980
Elastic ear cartilage and aortae from nine-day-old hamsters were incubated in Krebs-Ringer medium containing ascorbate, beta-aminopropionitrile and either [14C]proline or [3H]valine. The [14C]proline-labeled proteins were separated by chromatography on Agarose A-5 m in sodium dodecyl sulfate and their [14C]-hydroxyproline content measured.
P, Heeger, J, Rosenbloom
openaire   +2 more sources

Biocompatibility of silk-tropoelastin protein polymers

Biomaterials, 2014
Blended polymers are used extensively in many critical medical conditions as components of permanently implanted devices. Hybrid protein polymers containing recombinant human tropoelastin and silk fibroin have favorable characteristics as implantable scaffolds in terms of mechanical and biological properties. A firefly luciferase transgenic mouse model
Hongjuan, Liu, Steven G, Wise, Jelena, Rnjak-Kovacina, David L, Kaplan, Marcela M M, Bilek, Anthony S, Weiss, Jian, Fei, Shisan, Bao   +7 more
openaire   +2 more sources

Tropoelastin — A multifaceted naturally smart material

Advanced Drug Delivery Reviews, 2013
Tropoelastin dominates the physical performance of human elastic tissue as it is assembled to make elastin. Tropoelastin is increasingly appreciated as a protein monomer with a defined solution shape comprising modular, bridged regions that specialize in elasticity and cell attachment, which collectively participate in macromolecular assembly.
Suzanne M, Mithieux, Steven G, Wise, Anthony S, Weiss   +2 more
openaire   +2 more sources

Intrinsic enzyme activity associated with tropoelastin

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1976
The presence of an enzyme(s) associated with purified tropoelastin has been established. Results indicate that the enzyme(s) remains closely associated with the soluble elastin throughout the entire purification procedure suggesting that it is very tightly bound. Enzymatic activity is optimum through the pH range 7-9 (37 degrees C) and can be inhibited
R P, Mecham, J A, Foster, C, Franzblau
openaire   +2 more sources

Fibrillation of tropoelastin induced by proteoglycan

Experientia, 1976
Electrostatic interaction between tropoelastin, the native precursor of elastin, and proteoglycan results in tropoelastin fibrillation. The finding suggests a possible involvement of proteoglycans in elastogenesis.
M, Adam, V, Podrazký
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Tropoelastin purification: Improvements using enzyme inhibitors

Analytical Biochemistry, 1975
Abstract The true monomerix size of porcine aortic tropoelastin is 72,000–74,000 daltons. The newly modified isolation procedure we describe gives meterial predominantly of this molecular size with improved yields. The protein is extremely susceptible to proteolysis and steps must be taken during isolation to prevent this occurrence.
L B, Sandberg, E, Bruenger, E G, Cleary
openaire   +2 more sources

Polyclonal antibodies to tropoelastin and the specific detection and measurement of tropoelastinin vitro

Connective Tissue Research, 1991
Because tropoelastin is difficult to purify, most antibodies to elastin are raised against the insoluble form of the molecule. While these antibodies cross-react with tropoelastin, antigenic differences between insoluble and soluble elastin suggest that antibodies raised directly against tropoelastin might provide a more sensitive and specific reagent ...
I W, Prosser, L A, Whitehouse, W C, Parks, M, Stahle-Bäckdahl, A, Hinek, P W, Park, R P, Mecham   +6 more
openaire   +2 more sources