Results 251 to 260 of about 9,068 (269)
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Engineered Tropoelastin and Elastin-Based Biomaterials
2009Elastin is a key mammalian extracellular matrix protein that is critical to the elasticity, compliance, and resilience of a range of tissues including the vasculature, skin, and lung. In addition to providing mechanical integrity to tissues, elastin also has critical functions in the regulation of cell behavior and may help to modulate the coagulation ...
Steven G, Wise +2 more
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Tropoelastin Biosynthesis by Corneal Cells
Ophthalmologica, 2003The vertebrate cornea is an avascular tissue and does not contain elastic fibers. We tested the capacity of corneal epithelial cells and stromal keratocytes to synthesize tropoelastin. Explant cultures and cell cultures were obtained from these two cell types in standard culture conditions.
N. Isnard +3 more
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Structural changes and facilitated association of tropoelastin
Archives of Biochemistry and Biophysics, 2003Circular dichroism studies of tropoelastin secondary structure show 4+/-1% alpha-helix in aqueous solutions. This is in contrast to the substantially higher amounts (up to 23+/-7%) of alpha-helix predicted by computer algorithms, which propose that regions of alpha-helix are limited to the alanine-rich cross-linking domains.
Lisa D, Muiznieks +2 more
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Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2004
The vertebrate cornea is an avascular tissue and does not contain elastic fibers. We tested the capacity of corneal epithelial cells and stromal keratocytes to synthesize tropoelastin. Explant cultures and cell cultures were obtained from these two cell types in standard culture conditions.
N, Isnard +3 more
openaire +1 more source
The vertebrate cornea is an avascular tissue and does not contain elastic fibers. We tested the capacity of corneal epithelial cells and stromal keratocytes to synthesize tropoelastin. Explant cultures and cell cultures were obtained from these two cell types in standard culture conditions.
N, Isnard +3 more
openaire +1 more source
Cellular Expression of Tropoelastin mRNA Splice Variants
Matrix, 1992The primary transcript of tropoelastin is alternatively spliced into multiple mRNAs. The pattern and frequency of exon splicing is developmentally regulated, but the cellular profile of isoform expression within and among elastic tissues is not known.
W C, Parks +3 more
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Chick tropoelastin isolation and partial chemical characterization
Biochemical and Biophysical Research Communications, 1975Summary A method is described for the purification of tropoelastin from the aortas of copper-deficient chicks. The final product was suitable for sequencing. The first 35 N-terminal residues are presented. The N-terminal sequence is similar in many respects to the N-terminal sequence of porcine tropoelastin.
R B, Rucker +4 more
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Matrix Biology, 2005
A number of reports point to the presence of proteoglycans and/or glycosaminoglycans within elastic fibers in normal and in pathological conditions. We present data that heparan sulphate (HS)-containing proteoglycans are associated with normal elastic fibers in human dermis and that isolated HS chains interact in vitro with recombinant tropoelastin and
GHEDUZZI, Dealba +8 more
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A number of reports point to the presence of proteoglycans and/or glycosaminoglycans within elastic fibers in normal and in pathological conditions. We present data that heparan sulphate (HS)-containing proteoglycans are associated with normal elastic fibers in human dermis and that isolated HS chains interact in vitro with recombinant tropoelastin and
GHEDUZZI, Dealba +8 more
openaire +3 more sources
Journal of Biomaterials Applications, 2018
Valvular heart diseases lead to over 300,000 heart valve replacements worldwide each year. Commercially available bioprosthetic heart valves (BHVs) are mostly made from porcine or bovine pericardiums which were crosslinked by glutaraldehyde (GLUT ...
Yang Lei, Y. Xia, Yunbing Wang
semanticscholar +1 more source
Valvular heart diseases lead to over 300,000 heart valve replacements worldwide each year. Commercially available bioprosthetic heart valves (BHVs) are mostly made from porcine or bovine pericardiums which were crosslinked by glutaraldehyde (GLUT ...
Yang Lei, Y. Xia, Yunbing Wang
semanticscholar +1 more source