Results 71 to 80 of about 4,779 (198)

Lysyl Oxidase Enhances the Deposition of Tropoelastin through the Catalysis of Tropoelastin Molecules on the Cell Surface

Biological & Pharmaceutical Bulletin, 2017
The cross-linking of elastin by lysyl oxidase (LOX) family members is essential for the integrity and elasticity of elastic fibers, which play an important role in the characteristic resilience of various tissues. However, the temporal sequence of oxidation by LOX during elastic fiber formation is still incompletely understood.
Sato, Fumiaki, Seino-Sudo, Ryo, Okada, Mami, Sakai, Hiroyasu, Yumoto, Tetsuro, Wachi, Hiroshi   +5 more
openaire   +3 more sources

Recombinant human tropoelastin : production, properties and interactions [PDF]

, 1997
To enable the long-term study of tropoelastin and elastic fibre structure, function and biosynthesis, a recombinant system was developed to provide a source of human ...
Vrhovski, Bernadette
core  

Elastin in the Liver

Frontiers in Physiology, 2016
A characteristic feature of liver cirrhosis is the accumulation of large amounts of connective tissue with the prevailing content of type I collagen. Elastin is a minor connective tissue component in normal liver but it is actively synthesized by hepatic
Jiri Kanta
doaj   +1 more source

Bio‐inspired functional coacervates

Aggregate, 2022
Many functional coacervates have been identified in biological systems, which have attracted widespread interest. Coacervation is a liquid–liquid phase separation (LLPS) process in which a macromolecule‐enriched liquid phase is formed together with a ...
Shujun Chen, Qi Guo, Jing Yu
doaj   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, Volume 15, Issue 16, 24 April 2026.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Mechanistic Insight into the Elastin Degradation Process by the Metalloprotease Myroilysin from the Deep-Sea Bacterium Myroides profundi D25

Marine Drugs, 2015
Elastases have been widely studied because of their important uses as medicine and meat tenderizers. However, there are relatively few studies on marine elastases. Myroilysin, secreted by Myroides profundi D25 from deep-sea sediment, is a novel elastase.
Jie Yang, Hui-Lin Zhao, Bai-Lu Tang, Xiu-Lan Chen, Hai-Nan Su, Xi-Ying Zhang, Xiao-Yan Song, Bai-Cheng Zhou, Bin-Bin Xie, Anthony S. Weiss, Yu-Zhong Zhang   +10 more
doaj   +1 more source

Tailoring Multiphasic Protein Condensates via Liquid‐Liquid Phase Separation

Aggregate, Volume 7, Issue 4, April 2026.
Multiphasic protein condensates transform structural organizations and deliver nucleic acids. ABSTRACT Many of the membraneless organelles inside cells are multiphasic condensates with complex structural organizations driven by the demixing of phase‐separating proteins.
Yongxu Han, Kai Cheng, Kongqi Chen, Zhiyi Xu, Hao Jiang, Bin Zeng, Manjia Li, Fei Sun, Xiangze Zeng, Sijie Chen, Jiang Xia   +10 more
wiley   +1 more source

Macrophage Cluster of Differentiation 163 promotes post‐infarction cardiac repair and preserves left ventricular function via osteopontin

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
• Circulating soluble CD163 is elevated in ischaemic cardiomyopathy and correlates with systolic dysfunction severity and ventricular dilation. • Macrophage CD163 protects against post‐infarction systolic dysfunction and left ventricular dilation in mice. • Loss of CD163 decreases macrophage osteopontin expression.
Jingyu Chen, Linjian Chen, Wei Huang, Gang Wang, Lin Wang, Wanchun Mei, Wei Ni, Yang Liu, Licheng Ding, Xiaofeng Ge, Zhaokai Li, Jing Yu, Shufen Huang, Jiayi Lin, Yifan Chen, Binni Cai, Peng Zhang, Cuilian Dai, Binbin Liu   +18 more
wiley   +1 more source

Pathological investigations and correlation research of microfibrillar-associated protein 4 and tropoelastin in oral submucous fibrosis

BMC Oral Health, 2021
Background Oral submucous fibrosis (OSF), distinguished by abnormal collagen deposition, is a potentially malignant disorder with 4.2% (95% CI 2.7–5.6%) of malignant transformation and rising global prevalence.
Binjie Liu, Wenqun Gou, Hui Feng
doaj   +1 more source

Adipose-derived stromal cell secreted factors induce the elastogenesis cascade within 3D aortic smooth muscle cell constructs

Matrix Biology Plus, 2019
Objective: Elastogenesis within the medial layer of the aortic wall involves a cascade of events orchestrated primarily by smooth muscle cells, including transcription of elastin and a cadre of elastin chaperone matricellular proteins, deposition and ...
Aneesh K. Ramaswamy, Rachel E. Sides, Eoghan M. Cunnane, Katherine L. Lorentz, Leila M. Reines, David A. Vorp, Justin S. Weinbaum   +6 more
doaj   +1 more source