Results 81 to 90 of about 4,779 (198)
Polymorphisms in the human tropoelastin gene modify in vitro self-assembly and mechanical properties of elastin-like polypeptides. [PDF]
Elastin is a major structural component of elastic fibres that provide properties of stretch and recoil to tissues such as arteries, lung and skin. Remarkably, after initial deposition of elastin there is normally no subsequent turnover of this protein ...
David He +7 more
doaj +1 more source
Circulating desmosines may reflect arterial wall degeneration associated with atherosclerotic disease. Abstract Elastin, an extracellular matrix component that contributes to vascular integrity, is progressively degraded during vascular injury including atherosclerosis.
Hana Inoue +7 more
wiley +1 more source
dissertationA serum antibody, specific for tropoelastin was developed in rabbits. The tropoelastin antigen was extracted from the aortas of swine raised on a copper-deficient diet.
Snook, Valerie Kim
core
Background: Osteoarthritis (OA) is a debilitating degenerative joint disease, leading to significant pain and disability. Despite advancements, current regenerative therapies, such as mesenchymal stem cells (MSCs), face challenges in clinical efficacy ...
Junjun Yang +11 more
doaj +1 more source
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee +9 more
wiley +1 more source
Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro +6 more
wiley +1 more source
Tropoelastin is a flexible molecule that retains its canonical shape
Tropoelastin is the dominant building block of elastic fibers, which form a major component of the extracellular matrix, providing structural support to tissues and imbuing them with elasticity and resilience.
Giselle C. Yeo +10 more
core +1 more source
This study aimed to compare five protocols to optimize elastin purification, where purification protocols for elastin generally result in greatly damaged elastin fibres and this likely influences the biological response. The optimal protocol for elastin
A. M. Kadhim A. M. Kadhim +1 more
doaj +1 more source
Bioinspired Design of a Wet‐Adhesive Cornea Glue Based on Recombinant Human Protein Networks
Natures protein‐based high performance materials e.g. elastin, silk and muscle proteins have been mimicked by a new protein‐hybrid material based on redesigned human partial sequences only, showing high wet‐adhesiveness and elasticity for biomedical applications.
Anna Resch +17 more
wiley +1 more source
Functional and Structural Characterisation of Mutant Tropoelastin Constructs [PDF]
The major component of elastic fibres is elastin, formed from its soluble precursor, tropoelastin. The tropoelastin nanostructure is characterised by an N-terminal coil region, hinge region, bridge region and C-terminal foot region. Tropoelastin assembly
Yeo, Giselle
core

