Results 41 to 50 of about 44,311 (250)

Molecular mechanisms of the regulation of ATPase cycle in striated muscle [PDF]

open access: yes, 2007
New data on the molecular mechanism of the regulation of ATPase cycle by troponin-tropomyosin system have been obtained in reconstructed muscle fibers by using the polarized fluorescence technique, which allowed us following the azimuthal movements of ...
Yuri S. Borovikov   +2 more
core  

Possible Allergenic Role of Tropomyosin in Patients with Adverse Reactions after Fish Intake

open access: yes, 2018
In a recent case report, patient's anti-fish tropomyosin IgE was associated with gastrointestinal symptoms. We aimed to demonstrate on a wider scale that the panallergen tropomyosin should not be limited to invertebrate species and that clinically ...
Alguacil-Guillén, Marina   +3 more
core   +1 more source

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

open access: yesAdvanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng   +19 more
wiley   +1 more source

Steric blocking upside down: a different way of thinking about the competition between myosin and tropomyosin

open access: yesFrontiers in Physics
At low free Ca2+, the actin binding proteins tropomyosin, troponin I, troponin T and troponin C inhibit contraction in striated muscles. Ca2+ activation alters the position of tropomyosin on actin to uncover binding sites for high affinity forms of ...
Joseph M. Chalovich
doaj   +1 more source

Changing of expression actinbinding proteins in the kidney under dehydration

open access: yesВавиловский журнал генетики и селекции, 2018
Actin is related to main structural proteins in eukaryotes. In opposite to muscle alpha-actin, beta-actin is expressing in all types of cells. The constant reorganization of actin cytoskeleton takes place in non-muscle cells.
I. I. Khegay
doaj   +1 more source

Interaction of actin with dansyl‐tropomyosin [PDF]

open access: yesFEBS Letters, 1986
5‐[Dimethylamino]naphthalene‐1‐sulfonyl chloride (dansyl chloride) reacts with rabbit skeletal muscle tropomyosin (TM) to yield a highly fluorescent product, DNS‐TM. The extent of modification of TM can be regulated over a wide range, 0.3–15.5 dansyl groups per TM, depending upon the temperature and duration of the reaction.
Burtnick, L.D., Bhangu, K.
openaire   +2 more sources

Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development

open access: yesAdvanced Science, EarlyView.
Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu   +9 more
wiley   +1 more source

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

open access: yesJournal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes   +14 more
wiley   +1 more source

Tropomyosin autoantibodies associated with checkpoint inhibitor myositis

open access: yesOncoImmunology, 2020
This brief report details the measurement and identification of IgA antibodies to tropomyosin in a case of presumed ocular myositis with paraspinal myositis in a patient with metastatic uveal melanoma treated with checkpoint inhibitors.
Pauline Zaenker   +2 more
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

open access: yesAdvanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan   +6 more
wiley   +1 more source

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