Results 21 to 30 of about 34,865 (227)
Bioinformatics and Biology Insights, 2012 Cardiomyopathies are a major health problem, with inherited cardiomyopathies, many of which are caused by mutations in genes encoding sarcomeric proteins, constituting an ever-increasing fraction of cases.
Sunitha S Margaret +3 more
doaj +1 more source
A Proteomic Study of Atherosclerotic Plaques in Men with Coronary Atherosclerosis
Diagnostics, 2019 Background: To study the changes in protein composition of atherosclerotic plaques at different stages of their development in coronary atherosclerosis using proteomics.
Ekaterina M. Stakhneva +9 more
doaj +1 more source
Unique Sensitization Patterns to Allergen Components in a Crustacean-Allergic Australian Cohort. [PDF]
Clin Transl AllergyClinical and Translational Allergy, Volume 16, Issue 6, June 2026.
Johnston E +5 more
europepmc +2 more sources
Multisyringe Flow Injection Analysis of Tropomyosin Allergens in Shellfish Samples
Molecules, 2021 This paper presents the development and the application of a multisyringe flow injection analysis system for the fluorimetric determination of the major heat-stable known allergen in shrimp, rPen a 1 (tropomyosin).
Bruno Coulomb +4 more
doaj +1 more source
Food and Agricultural Immunology, 2019 Transglutaminase (TG) is a major food processing enzyme that induces protein cross-linking. Tropomyosin (TM) is a major shellfish allergen that is responsible for at least 80% of the shrimp allergic incidents.
Linglin Fu +3 more
doaj +1 more source
Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers
Journal of the American Heart Association, EarlyView., 2021 Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes +14 more
wiley +1 more source
Frontiers in Immunology, 2018 BackgroundIt has been shown earlier that there is a rise in the levels of autoantibodies and T cell response to cytoskeletal proteins in leprosy. Our group recently demonstrated a rise in both T and B cell responses to keratin and myelin basic protein in
Itu Singh +8 more
doaj +1 more source
Analysis of Treatment Patterns for Mucosal Melanoma Using Real-World Data in the SEER-Medicare-Linked Database. [PDF]
Cancer MedABSTRACT Background Mucosal melanoma (MM) is a rare, aggressive disease, often diagnosed late, and associated with poor survival. Surgical resection is the main potential curative option, but anatomical complexity limits feasibility, and real‐world evidence on treatment patterns remains scarce.
Zakeri M, Wagner S, Zhu X, Baser O.
europepmc +2 more sources
Identification of the pan-allergen tropomyosin from the common bed bug (Cimex lectularius)
Scientific ReportsTropomyosin is a muscle contraction protein documented across all animal life. Despite its ubiquity, its unique structure in invertebrates leads to allergic responses in humans that vertebrate tropomyosin does not.
Johnalyn M. Gordon, Zachary C. DeVries
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung +19 more
wiley +1 more source