Results 1 to 10 of about 44,311 (250)
cGMP interacts with tropomyosin and downregulates actin-tropomyosin-myosin complex interaction
Respiratory Research, 2018 Background The nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate (NO-sGC-cGMP) signaling pathway, plays a critical role in the pathogenesis of pulmonary arterial hypertension (PAH); however, its exact molecular mechanism remains ...
Lihui Zou +7 more
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Equilibrium self‐association of tropomyosin [PDF]
FEBS Letters, 2012 It has recently been reported that tropomyosin exists exclusively as a dimer in physiological salt conditions. It is shown in the present work using analytical ultracentrifugation that, on the contrary, tropomyosin is in equilibrium between monomer, dimer and tetramer with a weak tendency to dimerize and tetramerize. Such a finding has consequences for
Stafford, Walter F. +2 more
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Immuno-PCR for crustacean tropomyosin quantification [PDF]
, 2023 Tropomyosin has been recognized as one of the most common allergens among shellfish allergens. Sensitive and specific quantification of traces of allergens present in food samples is of critical importance for people with food allergies.
Ćirković Veličković, Tanja +4 more
core +11 more sources
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on TPM4 (tropomyosin ), with data on DNA, on the protein encoded, and where the gene is ...
Huret, JL, JL Huret
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β‐Tropomyosin mutations alter tropomyosin isoform composition
European Journal of Neurology, 2008 Background and purpose: Tropomyosin (TM) is an actin‐binding protein, which is localized head to tail along the length of the actin filament. There are three major TM isoforms in human striated muscle. Mutations in β‐tropomyosin (TPM2) have recently been identified as an important cause of neuromuscular disorders.
J, Nilsson, H, Tajsharghi
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The Binding Dynamics of Tropomyosin on Actin [PDF]
Biophysical Journal, 2001 REVTeX, 10 pages, 9 figures; to appear in Biophysical Journal; minor ...
Vilfan, Andrej
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European Journal of Cell Biology, 2022 Tropomodulin and tropomyosin are important components of sarcomeric thin filaments in striated muscles. Tropomyosin decorates the side of actin filaments and enhances tropomodulin capping at the pointed ends of the filaments.
Shoichiro Ono, Mario Lewis, Kanako Ono
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Frontiers in Cell and Developmental Biology, 2023 Tropomyosin is generally known as an actin-binding protein that regulates actomyosin interaction and actin filament stability. In metazoans, multiple tropomyosin isoforms are expressed, and some of them are involved in generating subpopulations of actin ...
Shoichiro Ono +7 more
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Current Biology, 2017 The actin cytoskeleton provides not only the underpinning for cell architecture but also mechanical force and the ability to drive movement of cells and their organelles. It is tempting to think of it simply as a set of stable structural elements, but nothing could be further from the truth.
Peter W, Gunning, Edna C, Hardeman
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iScience, 2022 Summary: The effects of N-terminal acetylation of the high molecular weight tropomyosin isoforms Tpm1.6 and Tpm2.1 and the low molecular weight isoforms Tpm1.12, Tpm3.1, and Tpm4.2 on the actin affinity and the thermal stability of actin-tropomyosin ...
Theresia Reindl +8 more
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