Results 281 to 290 of about 230,788 (365)

Exposure–Response Modeling and Simulation to Identify Optimal Mavacamten Posology When Coadministered with CYP3A4 and CYP2C19 Inhibitors in Patients with Obstructive HCM

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Mavacamten, a cardiac myosin inhibitor, is primarily metabolized by the cytochrome P450 (CYP) enzymes CYP2C19 and CYP3A4, and coadministration with strong CYP3A4 or CYP2C19 inhibitors was contraindicated in patients with obstructive hypertrophic cardiomyopathy (HCM) in the US Prescribing Information. This study assessed the safety and efficacy
Samira Merali   +7 more
wiley   +1 more source

Unexpected Giant Right Coronary Artery Aneurysm Diagnosed by Computed Tomography Angiography in the Emergency Department

open access: yesJournal of Clinical Ultrasound, EarlyView.
3D Volume Rendering coronary CTA reconstruction showing a giant thrombosed aneurysm of the proximal right coronary artery ABSTRACT Giant coronary artery aneurysms (GCAA) are usually defined as diameter > 8 mm or > 400% of the adjacent normal segment; they are very rare (reported prevalence ≈0.02%).
Stefano Giusto Picchi   +8 more
wiley   +1 more source

Troponin T switching in the developing rat heart.

open access: hybrid, 1988
L Saggin   +4 more
openalex   +1 more source

Bicontinuous Interconnected Porous Biomaterials for Tissue Engineering and Regeneration

open access: yesSmall Science, EarlyView.
Solvent transfer‐induced phase separation transforms bioinert polyethylene glycol diacrylate into bioactive scaffolds featuring bicontinuous interconnected porosity, with negative Gaussian curvature, and unique topographical patterning. These attributes enable stem cell attachment, proliferation, and differentiation without basement membrane matrix ...
Aihik Banerjee   +16 more
wiley   +1 more source

Enhanced external counter pulsation as a novel therapy to maintain cardiac output during hemodialysis: a preliminary randomized controlled study. [PDF]

open access: yesSci Rep
Thongsricome T   +6 more
europepmc   +1 more source

Isorhythmic atrioventricular dissociation during anaesthesia in a cat

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract A 10‐year‐old, male, neutered domestic shorthair cat with suspected hypertrophic cardiomyopathy was referred for cystotomy to remove uroliths present in its urinary bladder. Fifteen minutes after induction of general anaesthesia, atrioventricular dissociation was noted on the electrocardiogram with similar atrial and ventricular firing rates ...
Gemma Padrosa Sala   +3 more
wiley   +1 more source

Troponin, NT-proBNP and postoperative atrial fibrillation in a prospective cohort undergoing coronary artery bypass surgery. [PDF]

open access: yesSci Rep
Ohlrogge AH   +8 more
europepmc   +1 more source

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