Results 1 to 10 of about 100,576 (166)

Troponin I – a comprehensive review of its function, structure, evolution, and role in muscle diseases [PDF]

Animal Cells and Systems
The troponin complex is a critical component of thin filaments and plays an essential role in the calcium-mediated regulation of contraction and relaxation in striated muscles, including both cardiac and skeletal muscle.
Dongju Han, Younghyun Lim, Soah Lee, Seong-il Eyun   +3 more
doaj   +2 more sources

Myocardial Tissue Characterization in Patients with Hypertensive Crisis, Positive Troponin, and Unobstructed Coronary Arteries: A Cardiovascular Magnetic Resonance-Based Study

Diagnostics, 2023
Hypertensive crisis can present with cardiac troponin elevation and unobstructed coronary arteries. We used cardiac magnetic resonance (CMR) imaging to characterize the myocardial tissue in patients with hypertensive crisis, elevated cardiac troponin ...
Mohammed A. Talle, Anton F. Doubell, Pieter-Paul S. Robbertse, Sa’ad Lahri, Philip G. Herbst   +4 more
doaj   +1 more source

Variation in Troponin I Measurement and the Cardiovascular Management Approach Following Elevated Troponin I Among Critically Ill Patients With Sepsis

Critical Care Explorations, 2023
IMPORTANCE:. Troponin I is frequently elevated in sepsis, but optimal clinical approaches to diagnosis and management of troponin I during sepsis are unclear. OBJECTIVES:.
Michael A. Garcia, MD, Nicholas A. Bosch, MD, MSc, Ithan D. Peltan, MD, MSc, Allan J. Walkey, MD, MSc   +3 more
doaj   +1 more source

Cardiac Troponin T and Troponin I in the General Population

Circulation, 2019
There is great interest in widening the use of high-sensitivity cardiac troponins for population cardiovascular disease (CVD) and heart failure screening. However, it is not clear whether cardiac troponin T (cTnT) and troponin I (cTnI) are equivalent measures of risk in this setting. We aimed to compare and contrast (1) the association of cTnT and cTnI
Paul Welsh, Caroline Hayward, Anoop S V Shāh   +2 more
exaly   +3 more sources

Renal Elimination of Troponin T and Troponin I [PDF]

Clinical Chemistry, 2003
Cardiovascular complications represent the predominant cause of death in patients in the terminal stage of renal failure. Increased concentrations of cardiac troponin T (cTnT) may be a valuable predictor of cardiac risk (1)(2). However, cardiac troponin I (cTnI), clinical symptoms, and electrocardiogram (ECG) indications may be absent in patients with ...
Reinhard, Ziebig, Andreas, Lun, Berthold, Hocher, Friedrich, Priem, Claudia, Altermann, Gernot, Asmus, Hartmut, Kern, Rolfdieter, Krause, Babette, Lorenz, Rainer, Möbes, Pranav, Sinha   +10 more
openaire   +2 more sources

The Prognostic Significance of Troponin I and Troponin T [PDF]

Academic Emergency Medicine, 1998
Abstract. Objectives: To determine and compare the prognostic abilities of early, single‐sample measurements of cardiac troponin I (cTn‐I), cardiac troponin T (cTn‐T), creatine kinase‐MB (CK‐MB) among ED patients with possible myocardial ischemia. Methods: Prospective collection of clinical and serologic data using an identity‐unlinked technique from
G B, Green, D J, Li, E S, Bessman, J L, Cox, G D, Kelen, D W, Chan   +5 more
openaire   +2 more sources

Location of troponin I‐binding on troponin T sequence [PDF]

FEBS Letters, 1982
Interaction between troponin T and troponin I is considered as one of those necessary for the calI cium-regulatory mechanism in the thin filament of vertebrate striated muscles [ 1,2]. Studies using chymotryptic subfragments of troponin T showed that the affinity for troponin I is localized in the region of the C-terminal 101 residues, termed troponin ...
Tanokura, Masaru, Ohtsuki, Iwao
openaire   +2 more sources

Negative Troponin I as a Predictor of Survival in Patients With Coronavirus Disease 2019

International Journal of Cardiology: Heart & Vasculature, 2023
Background: Despite a large amount of evidence evaluating elevated troponin I levels and adverse clinical outcomes, little is known about the role of a normal (negative) troponin I during the first 24 h of admission for risk stratification in patients ...
Fergie J. Losiniecki, Jose Lopez, Majd Jazaerly, Kristina Menchaca, Vivek Kothari, Brendon Cornett, Christopher N. Ochner, Robert Chait   +7 more
doaj   +1 more source

Perbedaan Kadar Troponin T dan Troponin I Serum pada Berbagai Derajat Infeksi Virus Dengue Anak

Sari Pediatri, 2018
Latar belakang. Perbedaan kadar troponin T diketahui berhubungan dengan derajat infeksi virus dengue, tetapi belum diketahui pada troponin I. Tujuan. Mengetahui perbedaan kadar troponin T dan I pada berbagai derajat infeksi virus dengue anak.
Anthony Sudjadi, Dzulfikar DLH, Rahmat Budi Kuswiyanto   +2 more
doaj   +1 more source

Impact of genotype and phenotype on cardiac biomarkers in patients with transthyretin amyloidosis - Report from the Transthyretin Amyloidosis Outcome Survey (THAOS). [PDF]

PLoS ONE, 2017
AIM:Cardiac troponins and natriuretic peptides are established for risk stratification in light-chain amyloidosis. Data on cardiac biomarkers in transthyretin amyloidosis (ATTR) are lacking.
Arnt V Kristen, Mathew S Maurer, Claudio Rapezzi, Rajiv Mundayat, Ole B Suhr, Thibaud Damy, THAOS investigators   +6 more
doaj   +1 more source