Results 21 to 30 of about 21,232,041 (300)

Distinct conformational and functional effects of two adjacent pathogenic mutations in cardiac troponin I at the interface with troponin T

FEBS Open Bio, 2015
The α‐helix in troponin I (TnI) at the interface with troponin T (TnT) is a highly conserved structure. A point mutation in this region, A116G, was found in human cardiac TnI in a case of cardiomyopathy.
Shirin Akhter, J.-P. Jin
doaj   +1 more source

Troponin-I is not falsely elevated in asymptomatic dialysis patients

Saudi Journal of Kidney Diseases and Transplantation, 2013
Dialysis patients with troponin-I levels above the cut-off value diagnostic for acute myocardial event (AME) are sometimes labeled as having "renal cause" of elevated troponin-I.
Magdi M Hussein, Jaap M Mooij, Najla Al Malki, Tarek M Demerdash, Abdullah Y Mandourah   +4 more
doaj   +1 more source

Troponin I [PDF]

Circulation Research, 2002
Troponin is the key component of the calcium-dependent switch of the contractile apparatus in striated muscle. There are three subunits of troponin: troponin C, a Ca2+-binding calmodulin-like protein; troponin T, which attaches the complex to tropomyosin, anchoring it to the thin filament as well as having a regulatory role; and troponin I (TnI), named
openaire   +1 more source

False-positive troponin elevation due to an immunoglobulin-G-cardiac troponin T complex: a case report [PDF]

, 2020
Background Troponin is a crucial biomarker for the diagnosis of an acute coronary syndrome (ACS). It rises in response to myocardial injury from significant acute myocardial ischaemia caused by obstructive coronary artery disease [‘classical’ myocardial
Firoozi, S, Akhtar, Z., Shanmugam, N, Dargan, J, Gaze, D.C., Dargan, J., Collinson, P., Shanmugam, N., Akhtar, Z, Collinson, P, Gaze, D, Firoozi, S.   +11 more
core   +1 more source

Interaction of bepridil with the cardiac troponin C/troponin I complex [PDF]

FEBS Letters, 2001
We have investigated the binding of bepridil to calcium‐saturated cardiac troponin C in a cardiac troponin C/troponin I complex. Nuclear magnetic resonance spectroscopy and [15N,2H]cardiac troponin C permitted the mapping of bepridil‐induced amide proton chemical shifts. A single bepridil‐binding site in the regulatory domain was found with an affinity
Abusamhadneh, Ekram, Abbott, M.Bret, Dvoretsky, Alex, Finley, Natosha, Sasi, Soumya, Rosevear, Paul R.   +5 more
openaire   +2 more sources

Urine high–sensitive troponin I in children cannot offer an applicable alternative to serum

Frontiers in Cardiovascular Medicine
IntroductionIn children, congenital heart defects represent the primary cause of increased serum troponin I. The elimination process of cardiac troponin I from the bloodstream and the factors influencing this process remain unknown. The objective of this
Matija Bakoš, Daniel Dilber, Daniel Dilber, Anamarija Jazbec, Anamarija Jazbec, Tomo Svaguša, Ana-Meyra Potkonjak, Duje Braovac, Željko Đurić, Andrea Radeljak, Ana Lončar Vrančić, Hrvoje Vraneš, Slobodan Galić, Milivoj Novak, Ingrid Prkacin, Ingrid Prkacin   +15 more
doaj   +1 more source

Avaliação dos valores séricos de troponina I cardíaca em crianças menores de 1 ano de idade Evaluation of serum cardiac troponin I values in children less than 1 year of age

Brazilian Journal of Cardiovascular Surgery, 2008
OBJETIVO: Verificar os valores séricos para troponina I cardíaca em crianças abaixo de um ano de idade, sem disfunção cardíaca clínica. MÉTODOS: Os níveis séricos de troponina I cardíaca foram determinados em 99 crianças com idade abaixo de um ano ...
Antonio Carlos Arruda Souto, Werther Brunow de Carvalho   +1 more
doaj   +1 more source

Measurement of Calcium Dissociation Rates from Troponin C in Rigor Skeletal Myofibrils

Frontiers in Physiology, 2011
Ca2+ dissociation from the regulatory domain of troponin C may influence the rate of striated muscle relaxation. However, Ca2+ dissociation from troponin C has not been measured within the geometric and stoichiometric constraints of the muscle fiber ...
Sean C Little, Svetlana B Tikunova, Darl R. Swartz, Catalina eNorman, Jonathan P Davis   +4 more
doaj   +1 more source

Troponin T and Survival following Cardiac Surgery in Patients Supported with Extracorporeal Membrane Oxygenation for Post-Cardiotomy Shock

Diagnostics, 2023
Background: While troponin is an established biomarker of cardiac injury, its prognostic significance in post-cardiotomy cardiogenic shock patients supported by venoarterial extracorporeal membrane oxygenation (PCCS–VA-ECMO) remains unclear.
Małgorzata Celińska-Spodar, Marta Załęska Kocięcka, Ilona Kowalik, Piotr Kołsut, Ewa Sitkowska-Rysiak, Jarosław Szymański, Janina Stępińska   +6 more
doaj   +1 more source

HUBUNGAN KADAR GLUKOSA DARAH PUASA DENGAN TROPONIN I PADA PASIEN INFARK MIOKARD AKUT

An-Nadaa: Jurnal Kesehatan Masyarakat, 2022
Infark miokard akut (IMA) merupakan penyebab kematian tertinggi di dunia akibat terbentuk plak aterosklerotik, sehingga menyebabkan iskemia miokard. Hal ini memicu terjadinya nekrosis sel miokard yang menyebabkan gangguan sarkolema, sehingga terjadi ...
Ledy Oktabelia, Debie Anggraini, haves ashan   +2 more
doaj   +1 more source