Results 21 to 30 of about 113,140 (309)

Distinct conformational and functional effects of two adjacent pathogenic mutations in cardiac troponin I at the interface with troponin T

FEBS Open Bio, 2015
The α‐helix in troponin I (TnI) at the interface with troponin T (TnT) is a highly conserved structure. A point mutation in this region, A116G, was found in human cardiac TnI in a case of cardiomyopathy.
Shirin Akhter, J.-P. Jin
doaj   +1 more source

Troponin-I is not falsely elevated in asymptomatic dialysis patients

Saudi Journal of Kidney Diseases and Transplantation, 2013
Dialysis patients with troponin-I levels above the cut-off value diagnostic for acute myocardial event (AME) are sometimes labeled as having "renal cause" of elevated troponin-I.
Magdi M Hussein, Jaap M Mooij, Najla Al Malki, Tarek M Demerdash, Abdullah Y Mandourah   +4 more
doaj   +1 more source

Troponin I [PDF]

Circulation Research, 2002
Troponin is the key component of the calcium-dependent switch of the contractile apparatus in striated muscle. There are three subunits of troponin: troponin C, a Ca2+-binding calmodulin-like protein; troponin T, which attaches the complex to tropomyosin, anchoring it to the thin filament as well as having a regulatory role; and troponin I (TnI), named
openaire   +1 more source

Cardiac troponin I but not cardiac troponin T adheres to polysulfone dialyser membranes in an in vitro haemodialysis model: explanation for lower serum cTnI concentrations following dialysis.

, 2014
BACKGROUND: Elevated serum cardiac troponin T (cTnT) and I (cTnI) can occur in patients with chronic kidney disease. Differences in cTn concentrations between cTnT and cTnI have been reported but the mechanism of such discrepancy has not been ...
Collinson, PO, Gaze, D.C., David C Gaze, Collinson, P., Gaze, DC, Paul O Collinson   +5 more
core   +1 more source

Urine high–sensitive troponin I in children cannot offer an applicable alternative to serum

Frontiers in Cardiovascular Medicine
IntroductionIn children, congenital heart defects represent the primary cause of increased serum troponin I. The elimination process of cardiac troponin I from the bloodstream and the factors influencing this process remain unknown. The objective of this
Matija Bakoš, Daniel Dilber, Daniel Dilber, Anamarija Jazbec, Anamarija Jazbec, Tomo Svaguša, Ana-Meyra Potkonjak, Duje Braovac, Željko Đurić, Andrea Radeljak, Ana Lončar Vrančić, Hrvoje Vraneš, Slobodan Galić, Milivoj Novak, Ingrid Prkacin, Ingrid Prkacin   +15 more
doaj   +1 more source

Measurement of Calcium Dissociation Rates from Troponin C in Rigor Skeletal Myofibrils

Frontiers in Physiology, 2011
Ca2+ dissociation from the regulatory domain of troponin C may influence the rate of striated muscle relaxation. However, Ca2+ dissociation from troponin C has not been measured within the geometric and stoichiometric constraints of the muscle fiber ...
Sean C Little, Svetlana B Tikunova, Darl R. Swartz, Catalina eNorman, Jonathan P Davis   +4 more
doaj   +1 more source

Troponin T and Survival following Cardiac Surgery in Patients Supported with Extracorporeal Membrane Oxygenation for Post-Cardiotomy Shock

Diagnostics, 2023
Background: While troponin is an established biomarker of cardiac injury, its prognostic significance in post-cardiotomy cardiogenic shock patients supported by venoarterial extracorporeal membrane oxygenation (PCCS–VA-ECMO) remains unclear.
Małgorzata Celińska-Spodar, Marta Załęska Kocięcka, Ilona Kowalik, Piotr Kołsut, Ewa Sitkowska-Rysiak, Jarosław Szymański, Janina Stępińska   +6 more
doaj   +1 more source

Avaliação dos valores séricos de troponina I cardíaca em crianças menores de 1 ano de idade Evaluation of serum cardiac troponin I values in children less than 1 year of age

Brazilian Journal of Cardiovascular Surgery, 2008
OBJETIVO: Verificar os valores séricos para troponina I cardíaca em crianças abaixo de um ano de idade, sem disfunção cardíaca clínica. MÉTODOS: Os níveis séricos de troponina I cardíaca foram determinados em 99 crianças com idade abaixo de um ano ...
Antonio Carlos Arruda Souto, Werther Brunow de Carvalho   +1 more
doaj   +1 more source

HUBUNGAN KADAR GLUKOSA DARAH PUASA DENGAN TROPONIN I PADA PASIEN INFARK MIOKARD AKUT

An-Nadaa: Jurnal Kesehatan Masyarakat, 2022
Infark miokard akut (IMA) merupakan penyebab kematian tertinggi di dunia akibat terbentuk plak aterosklerotik, sehingga menyebabkan iskemia miokard. Hal ini memicu terjadinya nekrosis sel miokard yang menyebabkan gangguan sarkolema, sehingga terjadi ...
Ledy Oktabelia, Debie Anggraini, haves ashan   +2 more
doaj   +1 more source

The prognostic value of postoperative cardiac troponin I and T for major adverse cardiac events after coronary artery bypass grafting: a systematic review

BJA Open
Background: This systematic review describes the prognostic value of postoperative cardiac high-sensitive troponin I and T as risk markers for major adverse cardiac events (MACE) after coronary artery bypass graft (CABG) surgery and their predictive ...
Maaike S.Y. Thio, Peter G. Noordzij, Janice H. Klingenberg, Frieda Renkens, Lisette M. Vernooij, Olaf L. Cremer, Linda M. Posthuma, Thijs C.D. Rettig   +7 more
doaj   +1 more source