Results 11 to 20 of about 113,140 (309)

Cardiac biomarkers and COVID-19: A systematic review and meta-analysis

Journal of Infection and Public Health, 2021
Objective: To systematically investigate the relationship between cardiac biomarkers and COVID-19 severity and mortality. Methods: We performed a literature search using PubMed, Web of Science, and Google Scholar.
Wen An, Ju-Seop Kang, Qiuyang Wang, Tae-Eun Kim   +3 more
doaj   +1 more source

Troponin I, the Story [PDF]

Clinical Chemistry, 2010
Featured Article: Bodor GS, Porter S, Landt Y, Ladenson JH. Development of monoclonal antibodies for an assay of cardiac troponin I and preliminary results in suspected cases of myocardial infarction. Clin Chem 1992;38:2203–14.1 In the early 1980s, David N.
openaire   +2 more sources

High-sensitivity troponin I concentrations are a marker of an advanced hypertrophic response and adverse outcomes in patients with aortic stenosis [PDF]

, 2014
AIMS: High-sensitivity cardiac troponin I (cTnI) assays hold promise in detecting the transition from hypertrophy to heart failure in aortic stenosis.
Lang, Chim C., Langrish, Jeremy P, Langrish, Jeremy P., Newby, David E., Shah, Anoop, Dweck, Marc R, Alam, Shirjel, Mills, Nicholas L; id_orcid, McAllister, David A, Hunter, Amanda L., Cowell, S. Joanna, Boon, Nicholas A, Shah, Anoop S.V., Strachan, Fiona E, McAllister, David A., Maria Choy, Anna; id_orcid, Strachan, Fiona E., Boon, Nicholas A., Mills, Nicholas L., Dweck, Marc R., Shah, Anoop S. V., Newby, David E, Lang, Chim C.; id_orcid, Chin, Calvin W.L., Chin, Calvin W L, Chin, Calvin W. L., Joanna Cowell, S, Maria Choy, Anna, Walker, Simon, Lang, Chim C, Hunter, Amanda L   +30 more
core   +1 more source

The Solution Structure of a Cardiac Troponin C−Troponin I−Troponin T Complex Shows a Somewhat Compact Troponin C Interacting with an Extended Troponin I−Troponin T Component [PDF]

Biochemistry, 2002
We have investigated the structure of the cTnC-cTnI-cTnT(198-298) calcium-saturated, ternary cardiac troponin complex by small-angle scattering with contrast variation. Shape restoration was also applied to the scattering information resulting from the deuterated cTnC subunit, the unlabeled cTnI-cTnT(198-298) subunits, and the entire complex.
William T, Heller, Ekram, Abusamhadneh, Natosha, Finley, Paul R, Rosevear, Jill, Trewhella   +4 more
openaire   +2 more sources

Troponin Cut-Offs for Acute Myocardial Infarction in Patients with Impaired Renal Function—A Systematic Review and Meta-Analysis

Diagnostics, 2022
Identifying acute myocardial infarction in patients with renal disease is notoriously difficult, due to atypical presentation and chronically elevated troponin.
Jan Kampmann, James Heaf, Christian Backer Mogensen, Andreas Kristian Pedersen, Jeff Granhøj, Hans Mickley, Frans Brandt   +6 more
doaj   +1 more source

Is cardiac Troponin I Considered as A Predictor of In-hospital Mortality among COVID-19 Patients? A Retrospective Cohort Study [PDF]

Bulletin of Emergency and Trauma, 2022
Objective: To describe the levels of troponin I in COVID-19 patients and its role in the prediction of their inhospital mortality as a cardiac biomarker.
Mohammad Haji Aghajani, Roxana Sadeghi, Reza Miri, Mohammad Parsa Mahjoob, Fatemeh Omidi, Fatemeh Nasiri-Afrapoli, Asma Pourhosseingoli, Niloufar Taherpour, Amirmohammad Toloui, Mohammad Sistanizad   +9 more
doaj   +1 more source

An in silico analysis of troponin I mutations in hypertrophic cardiomyopathy of Indian origin. [PDF]

PLoS ONE, 2013
Hypertrophic Cardiomyopathy (HCM) is an autosomal dominant disorder of the myocardium which is hypertrophied resulting in arrhythmias and heart failure leading to sudden cardiac death (SCD).
Gayatri Ramachandran, Manoj Kumar, Deepa Selvi Rani, Venkateshwari Annanthapur, Narasimhan Calambur, Pratibha Nallari, Punit Kaur   +6 more
doaj   +1 more source

Troponin release following endurance exercise: is inflammation the cause? a cardiovascular magnetic resonance study [PDF]

, 2010
Background: The aetiology and clinical significance of troponin release following endurance exercise is unclear but may be due to transient myocardial inflammation.
Wong Joyce, Whyte, G, Prasad, SK, Whyte, Greg, Smith Gillian, Annette Dahl, Smith, Gillian, Wage, R, Godfrey, R, Wilson, M, Gillian Smith, Francisco D Alpendurada, Sharma Sanjay, Prasad, Sanjay, O'Hanlon Rory, George Keith, Wage, Riccardo, Pennell, DJ, Pennell Dudley J, Roughton, Michael, Prasad Sanjay K, Roughton Michael, George, Keith, Rory O'Hanlon, Alpendurada Francisco D, Mat Wilson, Pennell, Dudley, Roughton, M, Sharma, S, Dahl, Annette, Greg Whyte, Sanjay K Prasad, Wilson Mat, Dave Oxborough, Alpendurada, Francisco, O'Hanlon, Rory, Keith George, Oxborough, Dave, Godfrey Richard, Wage Riccardo, Wong, Joyce, Dahl, A, Whyte Greg, Wilson, Mat, Smith, G, Joyce Wong, Richard Godfrey, Sanjay Sharma, Wong, J, Alpendurada, FD, Oxborough, D, Oxborough Dave, O'Hanlon, R, Dudley J Pennell, Riccardo Wage, Godfrey, Richard, Sharma, Sanjay, Michael Roughton, Dahl Annette, George, K   +59 more
core   +1 more source

A study on elevation of troponin I in ischemic stroke as an independent prognostic marker of outcomes

Nepal Journal of Neuroscience, 2020
Background: Stroke is the second leading cause of death worldwide, comprising approximately 10% of all deaths. A substantial number of stroke patients have elevated cardiac troponin levels and are associated with poorer prognosis.
Pradeep Thapa, Jagdish Prasad Agrawal, Rajani Baniya   +2 more
doaj   +1 more source

Interaction of bepridil with the cardiac troponin C/troponin I complex [PDF]

FEBS Letters, 2001
We have investigated the binding of bepridil to calcium‐saturated cardiac troponin C in a cardiac troponin C/troponin I complex. Nuclear magnetic resonance spectroscopy and [15N,2H]cardiac troponin C permitted the mapping of bepridil‐induced amide proton chemical shifts. A single bepridil‐binding site in the regulatory domain was found with an affinity
Abusamhadneh, Ekram, Abbott, M.Bret, Dvoretsky, Alex, Finley, Natosha, Sasi, Soumya, Rosevear, Paul R.   +5 more
openaire   +2 more sources