Results 311 to 320 of about 238,995 (362)
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Emergency Medicine Clinics of North America, 2022
High-sensitivity cardiac troponin (hs-cTn) assays are highly specific to cardiac tissue and can detect small amounts of myocardial injury rapidly. Hs-cTn assays are the recommended cardiac biomarkers in the major US and European guidelines. In the appropriate clinical context, these assays allow clinicians to rapidly rule out a non-ST-elevation ...
Tyler Thomas, Hempel, Amy, Wyatt
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High-sensitivity cardiac troponin (hs-cTn) assays are highly specific to cardiac tissue and can detect small amounts of myocardial injury rapidly. Hs-cTn assays are the recommended cardiac biomarkers in the major US and European guidelines. In the appropriate clinical context, these assays allow clinicians to rapidly rule out a non-ST-elevation ...
Tyler Thomas, Hempel, Amy, Wyatt
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Clinica Chimica Acta
Cardiac troponin (cTn) testing plays a crucial role in the diagnosis of cardiovascular diseases, particularly acute coronary syndrome (ACS), which includes acute myocardial infarction (AMI). However, conventional immunoassays may be subject to interference from autoantibodies, cross-reactivity, and biotin-related effects, compromising diagnostic ...
Yumeng Gao +7 more
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Cardiac troponin (cTn) testing plays a crucial role in the diagnosis of cardiovascular diseases, particularly acute coronary syndrome (ACS), which includes acute myocardial infarction (AMI). However, conventional immunoassays may be subject to interference from autoantibodies, cross-reactivity, and biotin-related effects, compromising diagnostic ...
Yumeng Gao +7 more
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1999
Abstract Troponin (Tn) (for reviews see refs 1-6) is a complex of three subunits: troponin C (TnC), troponin I (Tnl), and troponin T (TnT); together with tropomyosin (TM) it constitutes the Ca2+- dependent regulatory machinery located in the actin filaments of striated muscle.
John Gergely +2 more
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Abstract Troponin (Tn) (for reviews see refs 1-6) is a complex of three subunits: troponin C (TnC), troponin I (Tnl), and troponin T (TnT); together with tropomyosin (TM) it constitutes the Ca2+- dependent regulatory machinery located in the actin filaments of striated muscle.
John Gergely +2 more
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Biochemistry, 1992
We have quantitated the interactions of two rabbit skeletal troponin C fragments with troponin I and the troponin I inhibitory peptide. The calcium binding properties of the fragments and the ability of the fragments to exert control in the regulated actomyosin ATPase assay have also been studied. The N- and C-terminal divalent metal binding domains of
C A, Swenson, R S, Fredricksen
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We have quantitated the interactions of two rabbit skeletal troponin C fragments with troponin I and the troponin I inhibitory peptide. The calcium binding properties of the fragments and the ability of the fragments to exert control in the regulated actomyosin ATPase assay have also been studied. The N- and C-terminal divalent metal binding domains of
C A, Swenson, R S, Fredricksen
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Revista Española de Cardiología (English Edition), 2015
Aitor Alquezar-Arbe y Jordi Ordonez-Llanos* a Servicio de Urgencias, Instituto de Investigacion Biomedica (IIB Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, Espana b Servicio de Bioquimica, Instituto de Investigacion Biomedica (IIB Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, Espana Departamento de Bioquimica y Biologia ...
Aitor, Alquézar-Arbé +1 more
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Aitor Alquezar-Arbe y Jordi Ordonez-Llanos* a Servicio de Urgencias, Instituto de Investigacion Biomedica (IIB Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, Espana b Servicio de Bioquimica, Instituto de Investigacion Biomedica (IIB Sant Pau), Hospital de la Santa Creu i Sant Pau, Barcelona, Espana Departamento de Bioquimica y Biologia ...
Aitor, Alquézar-Arbé +1 more
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International Journal of Cardiology, 2016
Cardiac troponins are the preferred biomarkers in diagnostic of myocardial infarction, but these markers also can rise in response to exercise. Multiple studies have assessed troponins post-exercise, but the results have varied and there have been disagreements about the mechanism of troponin release. The aim of this paper was to review the literature,
T, Gresslien, S, Agewall
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Cardiac troponins are the preferred biomarkers in diagnostic of myocardial infarction, but these markers also can rise in response to exercise. Multiple studies have assessed troponins post-exercise, but the results have varied and there have been disagreements about the mechanism of troponin release. The aim of this paper was to review the literature,
T, Gresslien, S, Agewall
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Perioperative Troponin Screening
Anesthesia & Analgesia, 2016Myocardial injury is the most common cause of death during the 30 days after noncardiac surgery. Only 14% of patients who are experiencing a perioperative myocardial infarction will have chest pain, and 65% are entirely clinically silent, which means that they will go undetected without routine troponin screening.
Daniel I, Sessler, P J, Devereaux
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Biochimica et Biophysica Acta (BBA) - Protein Structure, 1969
Abstract Troponin was isolated from preparations of the ethylene glycol bis-(β-aminoethyl ether)-N,N′-tetraacetic acid (EGTA)-sensitizing factor over the pH range of 3.5–4.6. The variations among troponins were due essentially to differences in the proportion and properties of the troponin A component.
D J, Hartshorne, M, Theiner, H, Mueller
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Abstract Troponin was isolated from preparations of the ethylene glycol bis-(β-aminoethyl ether)-N,N′-tetraacetic acid (EGTA)-sensitizing factor over the pH range of 3.5–4.6. The variations among troponins were due essentially to differences in the proportion and properties of the troponin A component.
D J, Hartshorne, M, Theiner, H, Mueller
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Biochemical and Biophysical Research Communications, 2008
The troponin complex was discovered over thirty years ago and since then much insight has been gained into how this complex senses fluctuating levels of Ca(2+) and transmits this signal to the myofilament. Advances in genetics methods have allowed identification of mutations that lead to the phenotypically distinct cardiomyopathies: hypertrophic ...
Audrey N, Chang +2 more
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The troponin complex was discovered over thirty years ago and since then much insight has been gained into how this complex senses fluctuating levels of Ca(2+) and transmits this signal to the myofilament. Advances in genetics methods have allowed identification of mutations that lead to the phenotypically distinct cardiomyopathies: hypertrophic ...
Audrey N, Chang +2 more
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Journal of Clinical Pathology, 2011
Sensitive troponin assays have been developed to meet the diagnostic goals set by the universal definition of myocardial infarction (MI). The analytical advantages of sensitive troponin assays include improved analytical imprecision at concentrations below the 99th percentile and the ability to define a reference distribution fully.
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Sensitive troponin assays have been developed to meet the diagnostic goals set by the universal definition of myocardial infarction (MI). The analytical advantages of sensitive troponin assays include improved analytical imprecision at concentrations below the 99th percentile and the ability to define a reference distribution fully.
openaire +2 more sources