Neuroprotective effects of Lycium barbarum polysaccharides against rat hippocampal apoptosis induced by chronic intermittent hypoxia [PDF]
, 2012 Poster presentationWe have shown neuronal apoptosis in the hippocampus of rats exposed to chronic intermittent hypoxia mimicking severe conditions of obstructive sleep apnea (OSA) syndrome in patients [1].
Fung, ML, Lam, CS, Tipoe, GL
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Microglia in Alzheimer's disease: a role for ion channels [PDF]
, 2018 Alzheimer's disease is the most common form of dementia, it is estimated to affect over 40 million people worldwide. Classically, the disease has been characterized by the neuropathological hallmarks of aggregated extracellular amyloid-β and ...
Dallas, Mark L. +4 more
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The Journal of Physiology, Volume 602, Issue 18, Page 4437-4456, 15 September 2024.Abstract figure legend Comparative analysis of mechanosensitive ion channels in mouse tissue‐resident and bone marrow‐derived macrophages. mRNA coding for the mechanosensitive ion channels Piezo1 and TRPV4 is found in both types of macrophages. Piezo1 activity is observed in the plasma membrane of bone marrow‐derived macrophages, but not in the ...
Ana Simon‐Chica +12 more
wiley +1 more source
Characterization of Ion Channels Involved in the Proliferative Response of Femoral Artery Smooth Muscle Cells [PDF]
, 2010 31 páginas, 6 figuras, adicionales 6 figuras y 3 tablas.[Objective]: Vascular smooth muscle cells (VSMCs) contribute significantly to occlusive vascular diseases by virtue of their ability to switch to a noncontractile, migratory, and proliferating ...
Barquín, Leire +7 more
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GATING AND PATHOGENIC MECHANISM OF POLYCYSTIN ION CHANNELS [PDF]
, 2023 Autosomal dominant polycystic kidney disease (ADPKD), one of the most common and life-threatening human genetic diseases, is caused by mutations in PKD1 or PKD2 genes.
Wang, Yan
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Cloning TRPC1 to enhance Calcium signal in a model of bitter taste transduction. [PDF]
, 2015 The sense of taste is used to evaluate the quality of food. In particular, animals detect at least five basic tastes: sweet, bitter, salty, umami and sour.
BARSOTTI, NOEMI
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Transient Receptor Potential Melastatin 8 Channel (TRPM8) Modulation: Cool Entryway for Treating Pain and Cancer [PDF]
, 2016 TRPM8 ion channels, the primary cold sensors in humans, are activated by innocuous cooling (
Ferrer-Montiel, Antonio +3 more
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Molecular mechanisms involved in the generation of calcium signals In insulin secreting cells. [PDF]
, 2014 Intracellular Ca 2+ regulates diverse cellular functions in almost all the cells. In the pancreatic ß-cells, Ca 2+ signals are critical for insulin secretion. An increase in the cytoplasmic free Ca 2+ concentration ([Ca 2+ ]i) triggers insulin secretion.
Krishnan, Kalaiselvan
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A polycystin-type transient receptor potential (Trp) channel that is activated by ATP. [PDF]
, 2016 ATP and ADP are ancient extra-cellular signalling molecules that in Dictyostelium amoebae cause rapid, transient increases in cytosolic calcium due to an influx through the plasma membrane.
Kay, Robert R, Traynor, David
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Die Rolle der Ca2+ -aktivierten K+ -Kanäle bei Endothelzellproliferation und Angiogenese [PDF]
, 2005 Am Anfang der Angiogenese im erwachsenen Organismus und insbesondere der Tumorvaskularisation steht die Aussprossung von Endothelzellen. Proangiogenetische Faktoren wie bFGF und VEGF stimulieren die Proliferation von Endothelzellen in vitro und die ...
Grgic, Ivica, Hoyer, Joachim (Prof. Dr.)
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