Results 131 to 140 of about 6,680,071 (237)

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source

A Bioassay for Available Amino Acids and True Metabolizable Energy in Feedingstuffs

Poultry Science, 1979
Abstract An experiment was made to determine if the basic methodology of the bioassay for true metabolizable energy (TME) can be applied to the measurement of available amino acids (AAA) in feedingstuffs. Administration of graded levels of glucose (0–30 g) had no effect on the excretion of 13 AA by adult roosters.
openaire   +1 more source

Metabolizable Energy Valueof-The Diets Containing Palm Kernel Cake (PKC) and Enzyme on The Kampongı Chicken at Nine Weeks Old [PDF]

, 2009
Kampong chicken is a local chicken rhat domesticated in Indonesia. It was a domestication's result from jungle fowl that domesticated in Bangladesh, Pakistan, India, Srilangka and Semenanjung Melayu:Kampong chickens are potensial as poultry meat source ...
Sumiati, Kurniasari, P., Iman Rahayu H.S.   +2 more
core   +1 more source

Does Choice of Estimators Influence Conclusions from True Metabolizable Energy Feeding Trials? [PDF]

, 2005
True metabolizable energy (TME) is a measure of avian dietary quality that accounts for metabolic fecal and endogenous urinary energy losses (EL) of non-dietary origin.
Sherfy, Mark H., Webb, Kenneth E., Jr., Kirkpatrick, Roy L.   +2 more
core  

Determination of the metabolizable energy content of common feedstuffs in meat-type growing ducks

, 2011
A trial was conducted using 275 growing Cherry Valley ducks to determine the apparent (AMEn) and true (TMEn) metabolizable energy corrected for nitrogen of maize, broken rice, rice bran, wheat bran, cassava meal, soybean meal and two fish meals with 550 ...
D.K. Oanh, T.Q. Viet, Sy, P. V., H.T. Hoai, Viet, T. Q., Oanh, D. K., P.V. Sy, Yen, N. T., N.V. Hop, N.T. Yen, Kinh, L. V., L.V. Kinh, Hoai, H. T., Hop, N. V.   +13 more
core   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

Apparent and true metabolizable energy and true digestibility of the essential amino acids of chickpeas (Cicer arietinum L.) experimented with adult roosters [PDF]

Using adapted for poultry methods for balance experiments, the content of zero nitrogen corrected apparent (AMEn) and true metabolizable energy (TMEn) and the true digestibility of the essential amino acids (TDEAA) of a stocking lot of Bulgarian ...
Chobanova, Sashka, Penkov, Dimo
core  

Cellular Mechanisms Enabling Mitochondria Transfer and Transplantation

Advanced Science, EarlyView.
Mitochondrial transfer and transplantation (mitoTT) is examined as a multistep process governed by distinct transfer routes and post‐transfer checkpoints. Mechanisms controlling mitochondrial uptake, network integration, cristae remodeling, mtDNA maintenance, immune sensing, and quality control are highlighted, revealing key biological and ...
F. Seyma Gokdemir, Yagmur Ozendi, Gokhan Burcin Kubat, Keshav K. Singh   +3 more
wiley   +1 more source

A comparison of two excreta collection techniques ( TRAY vs PLASTIC BAG) for amino acids digestibility and metabolizable energy determinations of rapeseed meals in adult cockerels

, 1993
Two techniques of excreta collection (tray and plastic hag) were compared to measure true digestibility of protein (TDP), amino acids (TDAA) and true metabolizable energy (TME) of rapeseed meals, obtained from whole seed (WRSM) and dehulled seed (DRSM ...
Perpustakaan UGM, i-lib
core   +1 more source

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

Advanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo, Katie Shi, Lina Kafadarian, Alexandra Bermudez, Johnny Diaz, Liam Edwards, Yunqi Hong, Ziyi Chen, Hyeonji Hwang, Weihong Yan, Alan Levinson, Robert Damoiseaux, Cho‐Jui Hsieh, Tanya Stoyanova, Andrew S. Goldstein, Neil Y.C. Lin   +15 more
wiley   +1 more source