Results 251 to 260 of about 10,867 (305)

Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer

Medicine Bulletin, EarlyView.
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei, Yunli Xu, Tianjiao Zhang, Shuyu Xu, Haonan Wang, Yuan Wang, Xinxin Xie, Xiaolong Liang   +7 more
wiley   +1 more source

Coyote (<i>Canis latrans</i>) Macronutrient Consumption and Diet Relative to Seasonality and Urbanization. [PDF]

Ecol Evol
Weiss KCB, Coogan SCP, Deviche P, Lewis JS, Hess SC, Schipper J, Strauss EG, Sterner B.   +7 more
europepmc   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Assessment of apparent metabolizable energy, and ileal amino acid digestibility of full-fat black soldier fly larvae (Hermetia illucens) in broiler chickens. [PDF]

Poult Sci
Alafif MS, Hoffman LC, Cozzolino D, Abdollahi MR, Roura E, Nguyen AD, Soumeh EA.   +6 more
europepmc   +1 more source

Loss‐of‐Function Variants in CPT1C: No Support for a Causal Role in Hereditary Spastic Paraplegia

Movement Disorders, EarlyView.
Abstract Background Hereditary spastic paraplegias (HSPs) are neurodegenerative disorders characterized by lower‐limb spasticity. Pathogenic variants in CPT1C have been implicated in HSP. Objective The objective of this study was to assess whether CPT1C loss‐of‐function (LOF) variants are causally associated with HSP.
Rui Zhu, Lang Liu, Mehrdad A. Estiar, Farnaz Asayesh, Jamil Ahmad, Meron Teferra, Grace Yoon, Mark Tarnopolsky, Kym M. Boycott, Nicolas Dupre, Patrick A. Dion, Oksana Suchowersky, Albena Jordanova, Yi‐Chung Lee, Giovanni Stevanin, Stephan Zuchner, Guy A. Rouleau, Ziv Gan‐Or   +17 more
wiley   +1 more source

Impact of increasing dietary energy on fattening steers growth performance, feed efficiency, and metabolic traits. [PDF]

Trop Anim Health Prod
Gado HM, Ahmed DA, Elghandour MMMY, De Palo P, D'Alessandro AG, Salem AZM.   +5 more
europepmc   +1 more source

Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Focused ultrasound is rapidly emerging as a novel technology for the development of symptomatic therapies and supporting disease‐modifying treatments for Parkinson's disease (PD). At the forefront of this development is thermoablation using high‐intensity focused ultrasound, an incisionless treatment that has been extensively tested in ...
Rikke Hahn Kofoed, Victor Schwartz Hvingelby, Jose A. Pineda‐Pardo, Javier Blesa, Steffen Paschen, Anurag Tandon, Juho Joutsa, Andreas Nørgaard Glud   +7 more
wiley   +1 more source

Energy Intake During the Transition Period Triggers Substantial Impacts on Body Weight, Milk Production Efficiency, Milk Composition and Blood Biochemical Constituents in Fat-Tailed Ewes. [PDF]

Vet Med Sci
Mousaie A, Ghaedifard MR, Azizpour R, Sadeghi AA.   +3 more
europepmc   +1 more source

Postexercise Lactate Clearance, T2 Relaxation, and J‐Modulation in Human Skeletal Muscle Measured With Double‐Quantum Filtered 1H MRS at 7 T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose 1H MRS lactate measurements are potentially valuable for studying energy metabolism in working skeletal muscle, but some technical obstacles need to be overcome. Spectral filtering to isolate the lactate signal from overlapping lipid resonances shows promise.
Kostiantyn Repnin, Vasco Rafael Rocha dos Santos, Veronika Cap, Roberta Frass‐Kriegl, Siegfried Trattnig, Graham J. Kemp, Martin Meyerspeer   +6 more
wiley   +1 more source

Deciphering macronutrient information about human milk. [PDF]

J Perinatol
Belfort MB, Stellwagen L, North K, Unger S, O'Connor DL, Perrin MT.   +5 more
europepmc   +1 more source