Results 51 to 60 of about 91,180 (283)

A New Hybrid Inversion Method for 2D Nuclear Magnetic Resonance Combining TSVD and Tikhonov Regularization

Journal of Imaging, 2021
This paper is concerned with the reconstruction of relaxation time distributions in Nuclear Magnetic Resonance (NMR) relaxometry. This is a large-scale and ill-posed inverse problem with many potential applications in biology, medicine, chemistry, and ...
Germana Landi, Fabiana Zama, Villiam Bortolotti   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Numerical investigation of a two-stage serial vibration isolation system using frequency response function based substructuring method

Advances in Mechanical Engineering, 2017
The mechanical system applied in industry and manufacturing fields is generally a complex multi-stage isolation system, which contains a lot of connection parts.
Rong Guo, Meng-jia Wang, Sheng-qi Zhou, Shan Qiu   +3 more
doaj   +1 more source

A Combined Use of TSVD and Tikhonov Regularization for Mass Flux Solution in Tibetan Plateau

Remote Sensing, 2020
Limited by the Gravity Recovery and Climate Experiment (GRACE) and GRACE Follow-On (GRACE-FO) measurement principle and sensors, the spatial resolution of mass flux solutions is about 2–3° in mid-latitudes at monthly intervals.
Tianyi Chen, Jürgen Kusche, Yunzhong Shen, Qiujie Chen   +3 more
doaj   +1 more source

Dynamic quantum clustering: a method for visual exploration of structures in data

, 2009
A given set of data-points in some feature space may be associated with a Schrodinger equation whose potential is determined by the data. This is known to lead to good clustering solutions.
B. D. Ripley, David Horn, E. Merzbacher, J. R. Klauder, Marvin Weinstein, R. O. Duda, R. Varshavsky   +6 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The selective truncated singular value decomposition estimation for ill-posed geophysical observation equations

Applied Mathematics in Science and Engineering
Ill-posed problems are prevalent in geodetic and geophysical data processing, significantly impacting the traditional least squares (LS) estimation.
Xinna Li, Ke Chen, Chaozhong Ma, Shumei Guo, Songhui Han   +4 more
doaj   +1 more source