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Machine learning models in trusted research environments -- understanding operational risks [PDF]

International Journal of Population Data Science, 2023
Introduction Trusted research environments (TREs) provide secure access to very sensitive data for research. All TREs operate manual checks on outputs to ensure there is no residual disclosure risk. Machine learning (ML) models require very large amount
Felix Ritchie, Amy Tilbrook, Christian Cole, Emily Jefferson, Susan Krueger, Esma Mansouri-Bensassi, Simon Rogers, Jim Smith   +7 more
doaj   +5 more sources

Next-Generation Capabilities in Trusted Research Environments: Interview Study

Journal of Medical Internet Research, 2022
BackgroundA Trusted Research Environment (TRE; also known as a Safe Haven) is an environment supported by trained staff and agreed processes (principles and standards), providing access to data for research while protecting ...
Sanaz Kavianpour, James Sutherland, Esma Mansouri-Benssassi, Natalie Coull, Emily Jefferson   +4 more
doaj   +5 more sources

Disclosure control of machine learning models from trusted research environments (TRE): New challenges and opportunities [PDF]

Heliyon, 2023
Introduction: Artificial intelligence (AI) applications in healthcare and medicine have increased in recent years. To enable access to personal data, Trusted Research Environments (TREs) (otherwise known as Safe Havens) provide safe and secure ...
Esma Mansouri-Benssassi, Simon Rogers, Smarti Reel, Maeve Malone, Jim Smith, Felix Ritchie, Emily Jefferson   +6 more
doaj   +2 more sources

Towards a standardised cross-sectoral data access agreement template for research: a core set of principles for data access within trusted research environments [PDF]

International Journal of Population Data Science, 2023
Introduction Trusted Research Environments (TREs) are secure computing environments that provide access to data for approved researchers to use in studies that can save and improve lives.
Rachel Brophy, Ester Bellavia, Maeve Groot Bluemink, Katharine Evans, Munisa Hashimi, Yemi Macaulay, Edel McNamara, Allison Noble, Paola Quattroni, Amanda Rudczenko, Andrew D Morris, Cassie Smith, Andy Boyd   +12 more
doaj   +2 more sources

Semi-automated data provenance tracking for transparent data production and linkage to enhance auditing and quality assurance in Trusted Research Environments [PDF]

International Journal of Population Data Science
Introduction We present a prototype solution for improving transparency and quality assurance of the data linkage process through data provenance tracking designed to assist Data Analysts, researchers and information governance teams in authenticating ...
Katherine O'Sullivan, Milan Markovic, Jaroslaw Dymiter, Bernhard Scheliga, Chinasa Odo, Katie Wilde   +5 more
doaj   +2 more sources

A UK Specification for Trusted Research Environments

International Journal of Population Data Science
Objectives The need for Trusted Research Environments (TREs) is clear. Several influential reports have highlighted that personal or sensitive data which have been collected for operational, commercial or governmental reasons need to be managed securely
Hari Sood, Simon Li, Tim Machin, Katie Oldfield, Antony Chuter, Jillian Beggs, Sonya Coleman, Dermot Kerr, Ed Chalstrey, Matthew Craddock, Jim Madge, David Sarmiento-Perez, James Robinson, Cian O'Donovan, Martin O'Reilly, Christian Cole   +15 more
doaj   +3 more sources

Trust and the Goldacre Review: why trusted research environments are not about trust. [PDF]

J Med Ethics, 2023
Graham M, Milne R, Fitzsimmons P, Sheehan M.   +3 more
europepmc   +4 more sources

Leonhard Med, a trusted research environment for processing sensitive research data

Journal of Integrative Bioinformatics
This paper provides an overview of the development and operation of the Leonhard Med Trusted Research Environment (TRE) at ETH Zurich. Leonhard Med gives scientific researchers the ability to securely work on sensitive research data.
Okoniewski Michal J., Wiegand Anna, Schmid Diana Coman, Bolliger Christian, Bovino Cristian, Belluco Mattia, Wüst Thomas, Byrde Olivier, Maffioletti Sergio, Rinn Bernd   +9 more
doaj   +5 more sources

Developing canonical ‘safe researcher’ training materials for trusted research environments

IASSIST Quarterly
Social science and humanities research infrastructures allow the sharing and safe use of confidential, sensitive data for research via physical safe havens.
Deborah Wiltshire
doaj   +2 more sources

Towards a UK federation of trusted research environments

International Journal of Population Data Science
Objectives Phase 1 of the DARE UK programme concluded in 2024 with a portfolio of architectures, designs and proofs-of-concept for a national federated network of trusted research environments (TREs).
Rob Baxter, DARE UK Delivery Team
doaj   +2 more sources