Results 51 to 60 of about 569,733 (281)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Iranian Physicians and Patients Attitude toward Truth Telling of Cancer

open access: yesمجله دانشکده پزشکی اصفهان, 2011
Background: Truth telling is found as one of the most important issues in physician-patient communication and all of the physicians are concerned with it in some way.
Ahmadreza Zamani   +4 more
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Critical Inquiry for the Social Good: Methodological Work as a Means for Truth-Telling in Education [PDF]

open access: yesCritical Questions in Education, 2016
This article questions the ubiquity of the term “critical” in methodological scholarship, calling for a renewed association of the term with projects concerned with social justice, truth-telling, and overt articulations of the social good.
Aaron M. Kuntz, Austin Pickup
doaj  

Powiedzieć prawdę o historii, wariant polski [Telling the truth about history, the Polish way]

open access: yesStudia Litteraria et Historica, 2016
Telling the truth about history, the Polish way Editorial   Powiedzieć prawdę o historii, wariant polski Artykuł ...
Agnieszka Kozik, Joanna Tokarska-Bakir
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

The ‘dead’ as agents of truth-telling: Lessons from Timor-Leste and the Indigenous repatriation movement [PDF]

open access: yes
Truth-telling, as it is understood within the liberal discourse and practice of transitional justice, centres around the idea of an individual human subject telling a narrative of harms that occurred in a past that is assumed now to be ‘past’. The ‘dead’
Fforde, C   +7 more
core   +1 more source

Truth telling in Australia\u27s historical narrative [PDF]

open access: yes, 2020
As it stands, the Australian narrative solely reflects the truth of the European settler with little acknowledgement of the truths of First Nations people.
Mencevska, Iva, Iva Mencevska
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Truth and Truth-telling [PDF]

open access: yes, 1999
Starr explores the ethical and legal implications of truth-telling in the context of the law. He examines the role of truth as both a foundational concept and a challenge in the legal system, emphasizing its significance in judicial processes, including ...
Starr, Kenneth W.
core  

Home - About - Disclaimer - Privacy