Results 61 to 70 of about 569,733 (281)

Litteraturen som cynisk praktik

open access: yesTidskrift för Litteraturvetenskap, 2016
Literature as Cynic Practice: Foucault’s Radicalization of Parrhesia and its Didactical Implications This article discusses Foucault’s view of literature as a counter-discourse, and as a specific way of truth-telling connected to Cynic practice ...
Peter Degerman
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Speaking truth while telling jokes

open access: yesThe European Journal of Humour Research
This article examines how Greek satirists who produce and present television and online satirical newscasts legitimise their work at the intersection of journalism, humour and political advocacy.
Antonis Porichis
doaj   +1 more source

Fact-Checking and Truth-Telling in an Age of Alternative Facts

open access: yesGenealogy+Critique, 2020
In an age of alternative facts, fact-checking has become almost second nature to critical thinkers who are concerned with the consequences of post-truth for the future of democracy.
Linda M. G. Zerilli
doaj   +2 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

open access: yesMolecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani   +7 more
wiley   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

Balancing truth-telling in the preservation of hope

open access: yes, 2011
Truth-telling in healthcare practice can be regarded as a universal communicative virtue; however, there are different views on what consequence it has for giving or diminishing hope.
Pernilla Pergert   +3 more
core   +1 more source

A New Perspective on Challenges in Truth-telling to Patients

open access: yesHealth, Spirituality and Medical Ethics, 2021
Background and Objectives: Patient autonomy is a recognized principle in modern medical ethics, and truth-telling to the patient; thus, it holds special importance for its contribution to this principle.
Jannat Mashayekhi   +2 more
doaj  

Being asked to tell an unpleasant truth about another person activates anterior insula and medial prefrontal cortex

open access: yesFrontiers in Human Neuroscience, 2015
Truth has been used as a baseline condition in several functional magnetic resonance imaging (fMRI) studies of deception. However, like deception, telling the truth is an inherently social construct, which requires consideration of another person’s ...
Melissa eLittlefield   +5 more
doaj   +1 more source

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