Results 41 to 50 of about 750,485 (276)

A New Perspective on Challenges in Truth-telling to Patients

open access: yesHealth, Spirituality and Medical Ethics, 2021
Background and Objectives: Patient autonomy is a recognized principle in modern medical ethics, and truth-telling to the patient; thus, it holds special importance for its contribution to this principle.
Jannat Mashayekhi   +2 more
doaj  

Disclosure of Spousal Death to Patients with Dementia: Attitude and Actual Behavior of Care Managers

open access: yesEuropean Journal of Investigation in Health, Psychology and Education, 2023
As the number of dementia patients increases, there is a need to protect patients’ right to know. However, in reality, there are cases in Japan where spouses’ deaths are concealed from patients.
Hisashi Kato   +3 more
doaj   +1 more source

A qualitative study of the Omani physicians’ lived experience with truth disclosure to cancer patient

open access: yes, 2013
Objectives: The purpose of this phenomenological Qualitative Study is to gain an in depth understanding of the nature and meaning of the experiences of physicians in relation to truth disclosure and ethics of veracity when diagnosing cancer.
A. Amer, Nazik AL-Zakri
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Attitudes toward Telling the Truth to Cancer Patients in Iran: A Review Article

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2016
Background: Patientsgenerallyhave the right to be informed of their condition,but the debate over the issue of truth disclosure is still present. The attempt of this study is to review the approaches toward truth- telling to cancer patients in Iran ...
Ali Karimi Rosveh   +3 more
doaj  

Professional liability insurance and medical error disclosure

open access: yesSwiss Medical Weekly, 2015
QUESTION UNDER STUDY: To examine medicolegal stakeholders’ views about the impact of professional liability insurance in Switzerland on medical error disclosure. METHODS: Purposive sample of 23 key medicolegal stakeholders in Switzerland from
Stuart McLennan   +3 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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