Results 51 to 60 of about 768,420 (292)
A New Perspective on Challenges in Truth-telling to Patients
Health, Spirituality and Medical Ethics, 2021 Background and Objectives: Patient autonomy is a recognized principle in modern medical ethics, and truth-telling to the patient; thus, it holds special importance for its contribution to this principle.
Jannat Mashayekhi +2 more
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Can Truth Be Borne Here? Disclosure and Ecclesial Repair After Abuse
Open TheologyThis constructive practical-theological essay argues that ecclesial repair after abuse requires more than improved policies, reporting systems, or adjudicative procedures.
Pardue Brett McKinley
doaj +1 more source
Perspectives About Breaking Bad News Among Medical Students of Qom University of Medical Sciences
Health, Spirituality and Medical Ethics, 2021 Background and Objectives: Undoubtedly, breaking bad news is one of the most difficult duties of a doctor. Not having this skill and not paying attention to its details can result in poor patient satisfaction, psychological morbidity, and weak clinical ...
Akram Haidari +3 more
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Professional liability insurance and medical error disclosure
Swiss Medical Weekly, 2015 QUESTION UNDER STUDY: To examine medicolegal stakeholders’ views about the impact of professional liability insurance in Switzerland on medical error disclosure. METHODS: Purposive sample of 23 key medicolegal stakeholders in Switzerland from
Stuart McLennan +3 more
doaj +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
The media in the face of truth: speaking, listening, and conversion
Social Communication EthicsThe article reflects on truth as a fundamental criterion for the functioning of the mass media. In the face of contemporary fascination with pluralism and fragmentariness, the oneness of truth is recalled, which has the power to integrate dispersed ...
Maciej Radej
doaj +1 more source