Results 41 to 50 of about 227,718 (306)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

The battle for the whistleblower : an interview with John Kiriakou [PDF]

open access: yes, 2019
Whistleblowing, or speaking truth to power, is complex. How truth telling is shaped is an important issue, as is the legitimacy of the individual who speaks out.
Bushnell, Alexis   +2 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Perspectives About Breaking Bad News Among Medical Students of Qom University of Medical Sciences

open access: yesHealth, Spirituality and Medical Ethics, 2021
Background and Objectives: Undoubtedly, breaking bad news is one of the most difficult duties of a doctor. Not having this skill and not paying attention to its details can result in poor patient satisfaction, psychological morbidity, and weak clinical ...
Akram Haidari   +3 more
doaj  

A Christian Librarians Response to Government Secrecy

open access: yes, 2007
The nature of Christian librarianship requires professionals to remain aware of current political decisions made in our government that directly affect the public’s access to relevant information.
Wagner, Dora
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Disclosure of Spousal Death to Patients with Dementia: Attitude and Actual Behavior of Care Managers

open access: yesEuropean Journal of Investigation in Health, Psychology and Education, 2023
As the number of dementia patients increases, there is a need to protect patients’ right to know. However, in reality, there are cases in Japan where spouses’ deaths are concealed from patients.
Hisashi Kato   +3 more
doaj   +1 more source

Heidegger, Correspondence Truth and the Realist Theology of Thomas Forsyth Torrance [PDF]

open access: yes, 1997
Within the context of Torrance\u27s larger concern to critique the re-trenchment of philosophical (epistemological) dualism in theology (and culture), there lies his desire to re-establish a proper understanding of correspondence truth.
Morrison, John D.
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Attitudes toward Telling the Truth to Cancer Patients in Iran: A Review Article

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2016
Background: Patientsgenerallyhave the right to be informed of their condition,but the debate over the issue of truth disclosure is still present. The attempt of this study is to review the approaches toward truth- telling to cancer patients in Iran ...
Ali Karimi Rosveh   +3 more
doaj  

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