Results 41 to 50 of about 17,268 (260)
Disclosure of Spousal Death to Patients with Dementia: Attitude and Actual Behavior of Care Managers
European Journal of Investigation in Health, Psychology and Education, 2023 As the number of dementia patients increases, there is a need to protect patients’ right to know. However, in reality, there are cases in Japan where spouses’ deaths are concealed from patients.
Hisashi Kato +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The media in the face of truth: speaking, listening, and conversion
Social Communication EthicsThe article reflects on truth as a fundamental criterion for the functioning of the mass media. In the face of contemporary fascination with pluralism and fragmentariness, the oneness of truth is recalled, which has the power to integrate dispersed ...
Maciej Radej
doaj +1 more source
Professional liability insurance and medical error disclosure
Swiss Medical Weekly, 2015 QUESTION UNDER STUDY: To examine medicolegal stakeholders’ views about the impact of professional liability insurance in Switzerland on medical error disclosure. METHODS: Purposive sample of 23 key medicolegal stakeholders in Switzerland from
Stuart McLennan +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Liwanag sa Dilim: Days of Darkness, Night of Light!
Philippine Journal of Otolaryngology Head and Neck Surgery, 2022 Light one candle for the strength that we need To never become our own foe And light one candle for those who are suffering Pain we learned so long ago Light one candle for all we believe in That anger not tear us apart And light ...
José Florencio Lapeña
doaj
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Conspiracy of silence in palliative care settings: multidisciplinary insights from a scoping review
Palliative Medicine in PracticeBACKGROUND: When critical information about diagnosis or prognosis is partially or fully withheld from patients, a conspiracy of silence (COS) may occur.
Maria-Francisca Ferreira-Nunes +1 more
doaj +1 more source