Opioid signaling and design of analgesics. [PDF]
Paul B, Sribhashyam S, Majumdar S.
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(435) Nausea and vomiting with oliceridine (TRV130), a novel μ receptor G protein Pathway Selective modulator (μ-GPS), vs morphine: an analysis of tolerability from a phase 2b randomized clinical trial [PDF]
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Opioids and opioid receptors; understanding pharmacological mechanisms as a key to therapeutic advances and mitigation of the misuse crisis. [PDF]
Lambert DG.
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Structural Modification and Development of <i>N</i>-(1,2,3,4-Tetrahydro-3-isoquinolinylmethyl)benzamide, BPR1M492, as a Potent and Rapid-Onset Opioid Analgesic with Reduced Withdrawal Symptoms. [PDF]
Chang PW +13 more
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Role of β-arrestin-2 in short- and long-term opioid tolerance in the dorsal root ganglia. [PDF]
Muchhala KH +3 more
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Knowledge graph and emerging trends in β-arrestin research on pain: a bibliometric analysis (1997-2025). [PDF]
Yu H, Ding X, Zhang Y, Yu Y, Wang X.
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Three-Dimensional Structural Insights Have Revealed the Distinct Binding Interactions of Agonists, Partial Agonists, and Antagonists with the µ Opioid Receptor. [PDF]
Li Z +7 more
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(432) Respiratory safety signal with oliceridine (TRV130), a novel μ receptor G protein pathway selective modulator (μ-GPS), vs morphine: a safety analysis of a Phase 2b randomized clinical trial [PDF]
N. Singla +4 more
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Biased Opioid Receptor Agonists: Balancing Analgesic Efficacy and Side-Effect Profiles. [PDF]
Ju J, Li Z, Liu J, Peng X, Gao F.
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Overview and Prospects of the Clinical Application of Oliceridine. [PDF]
Yi K, Sun W, Yu W, Chen S.
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