Biological activity of the aqueous extract of Lychnophora pinaster Mart [PDF]
, 2005 Lyophilized aqueous extract (LAE) from Lychnophora pinaster Mart (Asteraceae) aerial parts was evaluated in the search of possible biological activities.
Assunção, A. C. +6 more
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Brazilian Journal of Medical and Biological Research, 2007 Ampelozizyphus amazonicus Ducke is a tree commonly found in the Amazon region and an extract of its stem bark is popularly used as an antimalarial and anti-inflammatory agent and as an antidote to snake venom.
L.V. Rosas +9 more
doaj +1 more source
Economic analysis of animal disease control inputs at farm level: the case of trypanocide use in villages under risk of drug resistance in West Africa [PDF]
, 2010 This paper presents an economic analysis of the use of drugs (isometamidium and diminazene) in controlling African Animal Trypanosomosis (AAT), a serious disease of cattle and small ruminants in villages that exhibit resistance to isometamidium in ...
Affognon, Hippolyte D. +2 more
core
Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and development [PDF]
, 2014 Advocacy for better drugs and access to treatment has boosted the interest in drug discovery and development for Chagas disease, a chronic infection caused by the genetically heterogeneous parasite, Trypanosoma cruzi.
Araujo-Junior, Adalberto M. +7 more
core +1 more source
Computer-Aided Design and Synthesis of a New Class of PEX14 Inhibitors: Substituted 2,3,4,5-Tetrahydrobenzo[F][1,4]oxazepines as Potential New Trypanocidal Agents [PDF]
, 2021 Roberto Fino +12 more
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The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]
, 2005 Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O. +4 more
core +2 more sources
In Vivo Biological Evaluation of a Synthetic Royleanone Derivative as a Promising Fast-Acting Trypanocidal Agent by Inducing Mitochondrial-Dependent Necrosis [PDF]
, 2020 Rubén Martín‐Escolano +9 more
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Autophagic-related cell death of Trypanosoma brucei induced by bacteriocin AS-48
International Journal for Parasitology: Drugs and Drug Resistance, 2018 The parasitic protozoan Trypanosoma brucei is the causative agent of human African trypanosomiasis (sleeping sickness) and nagana. Current drug therapies have limited efficacy, high toxicity and/or are continually hampered by the appearance of resistance.
Marta Martínez-García +9 more
doaj +1 more source
BMC Microbiology, 2018 Background Tsetse flies (Diptera: Glossinidae) are the vectors of African trypanosomosis, the causal agent of sleeping sickness in humans and nagana in animals.
Güler Demirbas-Uzel +6 more
doaj +1 more source
Evaluating 5-nitrothiazoles as trypanocidal agents
, 2013 s.r.wilkinson@qmul.ac ...
Bot, Christopher +6 more
openaire +2 more sources