Results 141 to 150 of about 5,661 (215)

Benzopyrazine-Based Small Molecule Inhibitors As Trypanocidal and Leishmanicidal Agents: Green Synthesis, In Vitro, and In Silico Evaluations [PDF]

, 2021
Jonathan Rock, Daniel M. Garcia, Omar Espino, Shaila A. Shetu, Manuel Jesús Chan-Bacab, Rosa Moo‐Puc, Navin B. Patel, Gildardo Rivera, Debasish Bandyopadhyay   +8 more
openalex   +1 more source

Mapping the S1 and S1’ subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents

, 2020
Lorenzo Cianni, Carina Lemke, Erik Gilberg, Christian Feldmann, Fabiana Rosini, Fernanda dos Reis Rocho, Jean F. R. Ribeiro, Daiane Y. Tezuka, Carla D. Lopes, Sérgio de Albuquerque, Jürgen Bajorath, Stefan Laufer, Andrei Leitão, Michael Gütschow, Carlos A. Montanari   +14 more
openalex   +2 more sources

Synthesis and Biological Profiles of Some Benzimidazolyl-chalcones as Anti-leishmanial and Trypanocidal Agents

, 2021
Deto U. Jean-Paul N’Guessan, L. A. C. Kablan, A. Kacou, Christian Bories, S. Coulibaly, Drissa Sissouma, Philippe M. Loiseau, M. Ouattara   +7 more
openalex   +1 more source

Aziridine-2,3-dicarboxylate inhibitors targeting the major cysteine protease of Trypanosoma brucei as lead trypanocidal agents

, 2006
Radim Vičík, Verena Hoerr, Melanie Glaser, Martina Schultheis, Elizabeth Hansell, James H. McKerrow, Ulrike Holzgrabe, Conor R. Caffrey, Alicia Ponte‐Sucre, Heidrun Moll, August Stich, Tanja Schirmeister   +11 more
openalex   +1 more source

Mechanistic Exploration of <i>N</i>,<i>N'</i>-Disubstituted Diamines as Promising Chagas Disease Treatments. [PDF]

Pharmaceuticals (Basel)
Recio-Balsells AI, Reigada C, Mediavilla MG, Panozzo-Zénere E, Villarreal Parra M, Doyle PS, Engel JC, Pereira CA, Cricco JA, Labadie GR.   +9 more
europepmc   +1 more source

Design, Synthesis, In Vitro and In Silico Biological Evaluation of New Pyridine-2,5-Dicarboxylates Esters Bearing Natural Source Fragments as Anti-Trypanosomatid Agents. [PDF]

Pharmaceutics
Sánchez-Palestino LM, Moreno-Rodríguez A, Navarrete-Carriola DV, Martínez-Archundia M, López-Vargas M, Argueta-Figueroa L, Vázquez-Jiménez LK, Paz-González AD, Ortiz-Pérez E, Doyle MP, Rivera G.   +10 more
europepmc   +1 more source

Antiproliferative and Trypanocidal Activity of Ivermectin Bioconjugates. [PDF]

ACS Omega
Sulik M, Otto-Ślusarczyk D, Steverding D, Struga M, Huczyński A.   +4 more
europepmc   +1 more source

In Silico Studies and Biological Evaluation of Thiosemicarbazones as Cruzain-Targeting Trypanocidal Agents for Chagas Disease [PDF]

Lidiane Meier, Milena F. C. V. de Melo, Heitor R Abreu, Isabella M. e Oliveira, Larissa Sens, Thiago H. Doring, Renata Krogh, Adilson Beatriz, Adriano D. Andricopulo, Sumbal Saba, Aldo S. de Oliveira, Jamal Rafique   +11 more
openalex   +1 more source

Lipophilic conformationally constrained spiro carbocyclic 2,6‐diketopiperazine‐1‐acetohydroxamic acid analogues as trypanocidal and leishmanicidal agents: An extended SAR study [PDF]

, 2017
Grigoris Zoidis, Andrew Tsotinis, Alexandra Τsatsaroni, Martin C. Taylor, John M. Kelly, Antonia Efstathiou, Despina Smirlis, George Fytas   +7 more
openalex   +1 more source

Repurposing COVID-19 Compounds (via MMV COVID Box): Almitrine and Bortezomib Induce Programmed Cell Death in <i>Trypanosoma cruzi</i>. [PDF]

Pathogens
Bethencourt-Estrella CJ, López-Arencibia A, Lorenzo-Morales J, Piñero JE.   +3 more
europepmc   +1 more source