Results 161 to 170 of about 5,661 (215)

DB75, a Novel Trypanocidal Agent, Disrupts Mitochondrial Function in Saccharomyces cerevisiae

, 2020
C. A. Lanteri, Bernard L. Trumpower, R. R. Tidwell, S. R. Meshnick   +3 more
openalex   +1 more source

New derivatives of 6-nitrocoumarin-3-thiosemicarbazone exhibit improved antiparasitic activity in the placenta against <i>Trypanosoma cruzi</i> and <i>Toxoplasma gondii</i>. [PDF]

Antimicrob Agents Chemother
Rocha-Valderrama E, Rostán S, Fernández M, Liempi A, Castillo C, Mahler G, Galarza-Jarrin A, Costales JA, Pozo-Martínez J, Olea-Azar C, Otero L, Moncada-Basualto M.   +11 more
europepmc   +1 more source

Synthesis, structure-activity relationship and trypanocidal activity of pyrazole-imidazoline and new pyrazole-tetrahydropyrimidine hybrids as promising chemotherapeutic agents for Chagas disease

, 2019
M. Monteiro, Guilherme C. Lechuga, Leonardo da Silva Lara, Bernardo A. Souto, M.G. Viganó, Saulo Cabral Bourguignon, Cláudia M. Calvet, Francisco Odêncio Rodrigues de Oliveira, Carlos Roberto Alves, Franklin Souza‐Silva, Maurício Silva dos Santos, Mirian Cláudia de Souza Pereira   +11 more
openalex   +1 more source

Cystatin from Austrelaps superbus snake venom as a model for identifying potential inhibitors of Trypanosoma cruzi cruzain. [PDF]

J Venom Anim Toxins Incl Trop Dis
Díaz JJAR, Garay AFG, Kayano AM, Holanda R, Francisco AF, Kuehn CC, Soares AM, Vega C, Calderon LA.   +8 more
europepmc   +1 more source

Integrated <i>In Vitro</i> and <i>In Silico</i> Profiling of Piperazinyl Thiosemicarbazone Derivatives Against <i>Trypanosoma cruzi</i>: Stage-Specific Activity and Enzyme Inhibition. [PDF]

Pharmaceuticals (Basel)
Baldoni HA, Sbaraglini ML, Balcazar DE, Arias DG, Guerrero SA, Alba Soto CD, Cieslik W, Rogalska M, Polański J, Enriz RD, Jampilek J, Musiol R.   +11 more
europepmc   +1 more source

Mapping the S1 and S1’ subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents [PDF]

, 2019
Lorenzo Cianni, Carina Lemke, Erik Gilberg, Christian Feldmann, Fabiana Rosini, Fernanda dos Reis Rocho, Jean F. R. Ribeiro, Daiane Y. Tezuka, Carla D. Lopes, Sérgio de Albuquerque, Jürgen Bajorath, Stefan Laufer, Andrei Leitão, Michael Gütschow, Carlos A. Montanari   +14 more
openalex   +1 more source

Fexinidazole results in specific effects on DNA synthesis and DNA damage in the African trypanosome. [PDF]

PLoS Negl Trop Dis
Berg KE, Rogers I, Ramirez HM, Cornejo J, Durante IM, Hovel-Miner G.   +5 more
europepmc   +1 more source

Interventions for Neglected Diseases Caused by Kinetoplastid Parasites: A One Health Approach to Drug Discovery, Development, and Deployment. [PDF]

Pharmaceuticals (Basel)
Ebiloma GU, Alhejeli A, de Koning HP.
europepmc   +1 more source

Natural sesquiterpene lactones as potential Trypanocidal and Leishmanicidal agents

Natural Products Chemistry & Research, 2018
openaire   +1 more source

Semisynthetic Ecdysteroid Cinnamate Esters and tert-Butyl Oxime Ether Derivatives with Trypanocidal Activity. [PDF]

J Nat Prod
Háznagy MB, Girst G, Vágvölgyi M, Cholke K, Krishnan SR, Gertsch J, Hunyadi A.   +6 more
europepmc   +1 more source