Results 191 to 200 of about 5,661 (215)

New <i>Trypanosoma brucei</i> acting derivatives incorporating 1-(4-phenyl)adamantane and 1-(4-phenoxyphenyl)adamantane. [PDF]

RSC Med Chem
Stavropoulou K, Kaimaki A, Nikolaou M, Brown AK, Tsotinis A, Taylor MC, Kelly JM, Papanastasiou IP.   +7 more
europepmc   +1 more source

Exploring the Anti-Chagas Activity of <i>Zanthoxylum chiloperone</i>'s Seedlings Through Metabolomics and Protein-Ligand Docking. [PDF]

Plants (Basel)
de Bilbao NV, Giebelhaus RT, Dias RP, Ferreira ME, Martínez M, Velasco-Carneros L, Nam SL, de la Mata AP, Maréchal JD, Adou AI, Yaluff G, Serna E, Sylvestre M, Torres S, Schinini A, Galeano R, Fournet A, Harynuk JJ, Cebrián-Torrejón G.   +18 more
europepmc   +1 more source

Spiroplasma endosymbiont reduction of host lipid synthesis and Stomoxyn-like peptide contribute to trypanosome resistance in the tsetse fly Glossina fuscipes. [PDF]

PLoS Pathog
Awuoche EO, Smallenberger G, Bruzzese DL, Orfano A, Weiss BL, Aksoy S.   +5 more
europepmc   +1 more source

Exploration of innovative drug repurposing strategies for combating human protozoan diseases: Advances, challenges, and opportunities. [PDF]

J Pharm Anal
Hu S, Batool Z, Zheng X, Yang Y, Ullah A, Shen B.   +5 more
europepmc   +1 more source

The impact of probiotic administration on experimental in vitro and in vivo infection by Trypanosoma cruzi. [PDF]

Mem Inst Oswaldo Cruz
Batista DDGJ, Missagia LC, Demarque KC, de Oliveira GM, Batista MM, Soeiro MNC.   +5 more
europepmc   +1 more source

3-Bromopyruvate Impairs Mitochondrial Function in <i>Trypanosoma cruzi</i>. [PDF]

Pathogens
da Costa RO, Barreto-Campos D, Barbosa-de-Barros J, Frechiani G, Carvalho-Kelly LF, Carvalho-de-Araújo AD, Meyer-Fernandes JR, Dick CF.   +7 more
europepmc   +1 more source

In silico evaluation of N-aryl-1,10-phenanthroline-2-amines as potential inhibitors of T. cruzi GP63 zinc-metalloprotease by docking and molecular dynamics simulations. [PDF]

Sci Rep
Camargo PG, da Silva RB, Zuma AA, Garden SJ, Albuquerque MG, Rodrigues CR, da Silva Lima CH.   +6 more
europepmc   +1 more source

Trypanosoma evansi infection in Tunisia: current situation. [PDF]

Parasite
Gharbi M, Kamoun M, Khamassi M, Rekik S, Ben Smida B, Fekih Ahmed J, Boubaker C, Cecchi G, Gimonneau G, Desquesnes M.   +9 more
europepmc   +1 more source

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Methylating agents as trypanocides

Journal of Medicinal Chemistry, 1990
Methylating agents, such as streptozotocin, procarbazine, N-methyl-N-nitrosourea, dimethyl sulfate, 1,2-dimethylhydrazine, and a series of 1,2-bis(sulfonyl)-1-methylhydrazines synthesized in this laboratory, were evaluated and shown to be therapeutically active against murine models of African trypanosomiasis.
P G, Penketh, K, Shyam, A A, Divo, C L, Patton, A C, Sartorelli   +4 more
openaire   +2 more sources

Synthesis of sydnonimine derivatives as potential trypanocidal agents

Journal of Heterocyclic Chemistry, 2003
AbstractN‐(p‐Nitrophenoxy)carbonyl‐3‐morpholino‐sydnonimine (NCMS) has been prepared from 3‐morpholinosydnonimine hydrochloride. Using the Griess assay and the superoxide‐mediated reduction of ferricytochrome c, the nitric oxide (NO•) and superoxide anion (O2•‐) ‐ releasing properties in phosphate buffer pH 7.4 of this novel peroxynitrite donor was ...
Laurent Soulere, Frederic Bringaud, Pascal Hoffmann   +2 more
openaire   +1 more source