Results 101 to 110 of about 143,738 (310)

Genome-wide analysis of 30 -untranslated regions supports the existence of post-transcriptional regulons controlling gene expression in trypanosomes [PDF]

, 2013
In eukaryotic cells, a group of messenger ribonucleic acids (mRNAs) encoding functionally interrelated proteins together with the trans-acting factors that coordinately modulate their expression is termed a post-transcriptional regulon, due to their ...
Agüero, Fernan Gonzalo, Carmona, Santiago Javier, de Gaudenzi, Javier Gerardo, Frasch, Alberto Carlos C.   +3 more
core   +3 more sources

Bypassing Endocytic Barriers: Visualizing Membrane Fusion and Endosomal Escape of Cubic Phase Lipid Nanoparticles (Cubosomes)

Small, EarlyView.
This study uses advanced microscopy techniques, including transmission electron microscopy, scanning electron microscopy (SEM), cryogenic SEM, and live‐cell fluorescence imaging, to investigate lipid cubosome interactions with mammalian cells. It provides the first direct nanoscale evidence of cubosome membrane fusion with plasma and endosomal ...
Sue Lyn Yap, Chaitali Dekiwadia, Enrico Della Gaspera, Calum J. Drummond, Charlotte E. Conn, Nhiem Tran   +5 more
wiley   +1 more source

Prevalência de triatomíneos (Hemíptera: Reduviidae: Triatominae) infectados por Trypanosoma cruzi: sazonalidade e distribuição na região Ciénega do Estado de Jalisco, México Prevalence of triatomines (Hemíptera: Reduviidae: Triatominae) infected by Trypanosoma cruzi: seasonality and distribution in the Ciénega region of the State of Jalisco, Mexico

Revista da Sociedade Brasileira de Medicina Tropical, 2008
As características físico-geográficas da região Ciénega, Jalisco, México a tornam propícia para transmissão do Trypanosoma cruzi, causador da doença de Chagas.
César Gómez-Hernández, Karine Rezende-Oliveira, Agustín Cortés Zárate, Esperanza Cortés Zárate, Francisco Trujillo-Contreras, Luis Eduardo Ramirez   +5 more
doaj   +1 more source

CRISPR/Cas9-mediated endogenous C-terminal Tagging of Trypanosoma cruzi Genes Reveals the Acidocalcisome Localization of the Inositol 1,4,5-Trisphosphate Receptor*

Journal of Biological Chemistry, 2016
Methods for genetic manipulation of Trypanosoma cruzi, the etiologic agent of Chagas disease, have been highly inefficient, and no endogenous tagging of genes has been reported to date.
N. Lander, M. Chiurillo, Melissa Storey, A. Vercesi, R. Docampo   +4 more
semanticscholar   +1 more source

Evaluation of two candidate molecules—TCTP and cecropin—on the establishment of Trypanosoma brucei gambiense into the gut of Glossina palpalis gambiensis

Insect Science, EarlyView.
This study investigates the potential of enhancing the resistance of Glossina palpalis gambiensis to Trypanosoma brucei gambiense to mitigate the transmission of Human African Trypanosomiasis. We successfully cloned genes encoding proteins of interest in Sodalis strains, resulting in recombinant Sodalis (recSodalis) that were micro‐injected into the L3
François Sougal Ngambia Freitas, Linda De Vooght, Flobert Njiokou, Jan Van Den Abeele, Géraldine Bossard, Bernadette Tchicaya, Rosa Milagros Corrales, Sophie Ravel, Anne Geiger, David Berthier‐Teyssedre   +9 more
wiley   +1 more source

Molecular characterization of Trypanosoma cruzi Mexican strains and their behavior in the mouse experimental model

Revista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUCTION: For a long time, the importance of Chagas disease in Mexico, where many regarded it as an exotic malady, was questioned. Considering the great genetic diversity among isolates of Trypanosoma cruzi, the importance of this biological ...
César Gómez-Hernández, Karine Rezende-Oliveira, Gabriel Antônio Nogueira Nascentes, Lara Rocha Batista, Henrique Borges Kappel, José Alejandro Martinez-Ibarra, Francisco Trujillo Contreras, Eliane Lages-Silva, Luis Eduardo Ramírez   +8 more
doaj   +1 more source

The genetics and genomics of Trypanosoma cruzi [PDF]

, 2007
Trypanosoma cruzi is a kinetoplastid parasite that causes Chagas disease. Trypanosomes are unusual organisms in many aspects of its genetics and molecular and cellular biology and considered a paradigm of the exception of the rule in the eukaryotic ...
Vazquez, Martin Pablo
core  

Repurposing of terconazole as an anti Trypanosoma cruzi agent [PDF]

, 2019
Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. Currently there are no effective treatments for the chronic phase of the disease, when most patients are diagnosed, therefore the development of ...
Martínez Sayé, Melisa Soledad, Miranda, Mariana Reneé, Pereira, Claudio Alejandro, Reigada, Chantal, Valera Vera, Edward Augusto   +4 more
core   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

The FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk, Kamil Steczkiewicz, Mariusz Radkiewicz, Paweł Link‐Lenczowski, Przemysław Surowiecki, Karolina Sztompka, Kariona A. Grabińska, Jacek K. Nowak, Liliana Surmacz   +8 more
wiley   +1 more source

A Brief View of the Surface Membrane Proteins from Trypanosoma cruzi

Journal of Parasitology Research, 2017
Trypanosoma cruzi is the causal agent of Chagas' disease which affects millions of people around the world mostly in Central and South America. T. cruzi expresses a wide variety of proteins on its surface membrane which has an important role in the ...
Á. Pech-Canul, V. Monteón, R. Solis-Oviedo   +2 more
semanticscholar   +1 more source