Results 81 to 90 of about 83,341 (233)
Two new γ‐lactone derivatives, alterlactones A–B (1–2), and a known analogue, 3were isolated from Alternaria sp. HN‐17. Their structures were elucidated by NMR, HRESIMS and ECD calculations. Both 1 and 2 showed potent anti‐inflammatory activity. ABSTRACT Two γ‐lactone derivatives, alterlactones A‐B (1–2), along with one known analogue 3, were isolated ...
Yuru Sun +6 more
wiley +1 more source
Caracterização biológica e molecular de cepas de Trypanosoma cruzi isoladas durante o surto de doença de Chagas agudo em Santa Catarina: [dissertação] [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Biotecnologia, Florianópolis, 2010Estudos moleculares e de biologia demonstram que o táxon Trypanosoma cruzi é composto por ...
Pena, Darlene Aparecida
core
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
INTRODUCTION: For a long time, the importance of Chagas disease in Mexico, where many regarded it as an exotic malady, was questioned. Considering the great genetic diversity among isolates of Trypanosoma cruzi, the importance of this biological ...
César Gómez-Hernández +8 more
doaj
The aim of this study was to reevaluate the ecology of an area in the Atlantic Forest, southeast Brazil, where Chagas disease (CD) has been found to occur.
Maria Augusta Dario +10 more
doaj +1 more source
Tissue‐Resident Macrophage in Inflammation and Cancer
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang +13 more
wiley +1 more source
Abstract The nucleoside diphosphate kinase (NDK) is a key enzyme that controls the balance of nucleotide pools in all living organisms. Beyond this fundamental role, NDKs exert pleiotropic effects in many cellular processes, including cell development, signal transduction, differentiation, tumor metastasis, and gene expression. The quaternary structure
Julie Kerboeuf +10 more
wiley +1 more source
Estudo da resposta inflamatória durante a infecção por Trypanosoma rangeli [PDF]
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.O protozoário parasito não virulento Trypanosoma rangeli tem sido proposto como um possível vetor vacinal na proteção contra Trypanosoma cruzi, agente ...
Morales, Stefanny Lucía Viloche
core
New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites:an open resource [PDF]
Using whole-cell phenotypic assays, the GlaxoSmithKline high-throughput screening (HTS) diversity set of 1.8 million compounds was screened against the three kinetoplastids most relevant to human disease, i.e.
Barroso, Vanessa +26 more
core +1 more source

