Results 101 to 110 of about 78,503 (217)

Metabolic changes that allow Plasmodium falciparum artemisinin-resistant parasites to tolerate oxidative stress

Frontiers in Parasitology
Artemisinin-based treatments (ACTs) are the first therapy currently used to treat malaria produced by Plasmodium falciparum. However, in recent years, increasing evidence shows that some strains of P.
Alejandro David Bonive-Boscan, Alejandro David Bonive-Boscan, Héctor Acosta, Ascanio Rojas   +3 more
doaj   +1 more source

Edelfosine (ET-18-OCH3) a Promising Alkylphospholipid against Resistant Trichomonas vaginalis

Proceedings, 2017
Edelfosine (ET-18-OCH3) is an alkylphospholipid with an analogous structure to miltefosine. Both molecules are active against kinetoplastids (Leishmania spp., Trypanosoma cruzi and Trypanosoma brucei). [...]
Alexandra Ibáñez-Escribano, Jose Antonio Escario, Faustino Mollinedo, Alicia Gómez-Barrio   +3 more
doaj   +1 more source

Using prodigiosin against some gram-positive and gram-negative bacteria and Trypanosoma cruzi

Journal of Venomous Animals and Toxins including Tropical Diseases
Background: This work aimed to explore the action of natural prodigiosin on both bacterial organisms and Trypanosoma cruzi cells. Methods: Natural prodigiosin pigment was extracted and purified from cultures of Serratia marcescens.
Rocío Herráez, Anna Mur, Alexandra Merlos, Miguel Viñas, Teresa Vinuesa   +4 more
doaj   +1 more source

Biology of Trypanosoma cruzi: An update Biología del Trypanosoma cruzi: Actualización

Infectio, 2012
Chagas disease, an illness caused by the protozoan Trypanosoma cruzi, is clinically and epidemiologically important in Latin America, and particularly in Brazil.
André Vianna Martins, Andréia Patrícia Gomes, Eduardo Gomes de Mendonça, Juliana Lopes Rangel Fietto, Luiz Alberto Santana, Maria Goreti de Almeida Oliveira, Mauro Geller, Ramon de Freitas Santos, Rodrigo Roger Vitorino, Rodrigo Siqueira-Batista   +9 more
doaj  

Cloning and Characterization of the Gene Encoding the Heat Shock Protein HSP83 from Trypanosoma cruzi

Uniciencia
[Objective] Trypanosoma cruzi, a causal agent of Chagas’ disease, is a parasite whose life cycle alternates between an invertebrate (triatomine) and a vertebrate (mammal) host. Various studies have shown that in T.
Ana Fernández, Ana Rita De Lima, Elizabeth Ferrer   +2 more
doaj   +1 more source

Exploring Trypanosoma cruzi transmission dynamics in an acute Chagas disease outbreak using next-generation sequencing

Parasites & Vectors
Background Chagas disease (CD), caused by Trypanosoma cruzi, poses a major global public health challenge. Although vector-borne transmission is the primary mode of infection, oral transmission is increasingly concerning. Methods This study utilized long-
Lissa Cruz-Saavedra, Carlos Ospina, Stivenn A. Gutiérrez, Jeiczon Jaimes-Dueñez, Omar Cantillo-Barraza, Carolina Hernández, Francisco Álvarez, María Blanco, Bernardo Leal, Lida Martínez, Manuel Medina, Mabel Medina, Silvia Valdivieso, Lauren Natalia Ramirez Celis, Luz H. Patiño, Juan David Ramírez   +15 more
doaj   +1 more source

Identification of a small RNA containing the trypanosome spliced leader: a donor of shared 5' sequences of trypanosomatid mRNAs? [PDF]

, 1984
The 35 nucleotide spliced leader (SL) sequence is found on the 5' end of numerous trypanosome mRNAs, yet the tandemly organized reiteration units encoding this leader are not detectably linked to any of these structural genes. Here we report the presence
Agabian, N, Milhausen, M, Nelson, RG, Sather, S, Selkirk, M   +4 more
core  

Review of Chagas Disease and Treatment Obstacles to Eradication [PDF]

, 2019
The World Health Organization and the Center for Disease Control reports Chagas disease, or American trypanosomiasis, as a major neglected tropical disease prevalent in 21 endemic Latin American countries.
Sherman, Emily
core   +1 more source

Trypanosoma cruzi prevalence and clinical forms in blood donor candidates in Brazil

Revista de Saúde Pública
The prevalence and clinical forms of Trypanosoma cruzi were evaluated among blood donor candidates attended at a general hospital in Rio de Janeiro, Brazil, from January 1997 to April 1999.
H J Silveira, O N Mozart, A N Norberg, E A Pile   +3 more
doaj  

Alta parasitemia pelo Trypanosoma cruzi em paciente com lupus eritematoso sistêmico

Revista da Sociedade Brasileira de Medicina Tropical, 2003
É descrito um caso de doença de Chagas com alta parasitemia pelo Trypanosoma cruzi em paciente com lupus eritematoso sistêmico. O xenodiagnóstico foi útil na identificação da parasitemia e o benznidazol foi capaz de reduzir a alta e incomum parasitemia ...
Leopoldo Luiz dos Santos-Neto, Máira F. Polcheira, Cleudson Castro, Rodrigo Aires Corrêa Lima, César Kozak Simaan, Francisco Aires Corrêa-Lima   +5 more
doaj