Results 111 to 120 of about 137,285 (295)

Trypanosoma madeirae sp. n.: A species of the clade T. cruzi associated with the neotropical common vampire bat Desmodus rotundus

International Journal for Parasitology: Parasites and Wildlife, 2019
Molecular phylogenetic studies have revealed the growing diversity of bat trypanosomes. Here, 14 isolates from blood samples of the vampire bat Desmodus rotundus (Phyllostomidae) from Rio de Janeiro, Southeast Brazil, were cultivated, and morphologically
Juliana H.S. Barros, Luciana Lima, Armando O. Schubach, Marta M.G. Teixeira   +3 more
doaj  

Between a bug and a hard place: Trypanosoma cruzi genetic diversity and the clinical outcomes of Chagas disease

Expert Review of Anti-Infective Therapy, 2015
Over the last 30 years, concomitant with successful transnational disease control programs across Latin America, Chagas disease has expanded from a neglected, endemic parasitic infection of the rural poor to an urbanized chronic disease, and now a ...
L. Messenger, M. Miles, C. Bern
semanticscholar   +1 more source

Sequence variation in CYP51A from the Y strain of Trypanosoma cruzi alters its sensitivity to inhibition [PDF]

, 2014
CYP51 (sterol 14α-demethylase) is an efficient target for clinical and agricultural antifungals and an emerging target for treatment of Chagas disease, the infection that is caused by multiple strains of a protozoan pathogen Trypanosoma cruzi.
Cherkesova, Tatiana S., Ges, Igor, Hargrove, Tatiana Y., Lepesheva, Galina I., Romano, Patricia Silvia, Usanov, Sergey A., Vanrell, Maria Cristina   +6 more
core   +1 more source

Cutaneous reactions during treatment with Nifurtimox or Benznidazole among Trypanosoma cruzi seropositive adults without symptomatic cardiomyopathy: A safety sub analysis of a placebo‐controlled randomised trial

Tropical Medicine &International Health, Volume 30, Issue 7, Page 673-684, July 2025.
Abstract Objectives To determine, in a randomised placebo‐controlled trial, if cutaneous adverse reactions during treatment (CARDT) with Benznidazole occur as often as with Nifurtimox, and whether the dose and duration of treatment change that frequency.
Juan Carlos Villar, María Fernanda Saavedra, Pablo Andrés Bermúdez, Eliana Váquiro Herrera, Skarlet Marcell Vásquez, Helena Arango, Antonia Camacho, Mario Javier Olivera   +7 more
wiley   +1 more source

CRISPR/Cas9-Induced Disruption of Paraflagellar Rod Protein 1 and 2 Genes in Trypanosoma cruzi Reveals Their Role in Flagellar Attachment

mBio, 2015
Trypanosoma cruzi is the etiologic agent of Chagas disease, and current methods for its genetic manipulation have been highly inefficient. We report here the use of the CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR ...
N. Lander, Zhu-Hong Li, S. Niyogi, R. Docampo   +3 more
semanticscholar   +1 more source

Chagas disease reactivation in a heart transplant patient infected by domestic Trypanosoma cruzi discrete typing unit I (TcIDOM) [PDF]

, 2015
Background Trypanosoma cruzi, causative agent of Chagas disease, displays high intraspecific genetic diversity: six genetic lineages or discrete typing units (DTUs) are currently recognized, termed TcI through TcVI.
Bhattacharyya, T., Burleigh, B.A., Costales, J.A., Garcia-Perez, J., Kotton, C.N., Llewellyn, M.S., Messenger, L.A., Zurita-Leal, A.C.   +7 more
core   +2 more sources

Electrochemical Behavior of Nitrofurazone in Aqueous Media Applying Multi‐Walled Carbon Nanotubes and Cu‐Phthalocyanine

Electroanalysis, Volume 37, Issue 6, June 2025.
Under alkaline conditions (pH > 9), hydroxyl ions promote the formation of Cu(OH)2 on the CuPc surface, which is electrochemically oxidized to generate Cu(III) (CuOOH). This high‐valent copper species acts as an electron‐transfer mediator, facilitating the one‐electron reduction of nitrofurazone to its nitro‐anion radical (R‐NO2•−) and subsequently ...
Charles L. Brito, Elizabeth I. Ferreira, Mauro A. La‐Scalea   +2 more
wiley   +1 more source

Molecular characterization of Trypanosoma cruzi Mexican strains and their behavior in the mouse experimental model Caracterização molecular de cepas mexicanas de Trypanosoma cruzi e seu comportamento no modelo experimental do camundongo

Revista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUCTION: For a long time, the importance of Chagas disease in Mexico, where many regarded it as an exotic malady, was questioned. Considering the great genetic diversity among isolates of Trypanosoma cruzi, the importance of this biological ...
César Gómez-Hernández, Karine Rezende-Oliveira, Gabriel Antônio Nogueira Nascentes, Lara Rocha Batista, Henrique Borges Kappel, José Alejandro Martinez-Ibarra, Francisco Trujillo Contreras, Eliane Lages-Silva, Luis Eduardo Ramírez   +8 more
doaj  

Busca retrospectiva da transmissão maternal da infecção chagásica em pacientes na fase crônica A retrospective search for maternal transmission of Chagas infection from patients in the chronic phase

Revista da Sociedade Brasileira de Medicina Tropical, 2004
Avaliamos a transmissão maternal do Trypanosoma cruzi em 278 filhos de 145 mães com a doença crônica causada por esse protozoário, nascidos após o estabelecimento do diagnóstico materno.
Anis Rassi, Vicente Amato Neto, Gustavo Gabriel Rassi, Valdir Sabbaga Amato, Anis Rassi Júnior, Alejandro O. Luquetti, Sérgio Gabriel Rassi   +6 more
doaj   +1 more source

The burden of congenital Chagas disease and implementation of molecular diagnostic tools in Latin America [PDF]

, 2018
It is estimated that between 8000 and 15 000 Trypanosoma cruzi infected babies are born every year to infected mothers in Chagas disease endemic countries. Currently, poor access to and performance of the current diagnostic algorithm, based on microscopy
Cruz, Israel, Katz, Zachary, Ndung'u, Joseph Mathu, Picado, Albert, Redard Jacot, Maël, Schijman, Alejandro Gabriel, Sosa-Estani, Sergio Alejandro, Torrico, Faustino   +7 more
core   +1 more source