Results 121 to 130 of about 143,738 (310)
Revista de Saúde Pública, 1976 Relata-se um novo encontro do Trypanosoma (Megatrypanum) freitasi, raro tripanosomatídeo encontrado no sangue de marsupiais, do gênero Didelphis.
Eduardo Olavo da Rocha e Silva +2 more
doaj +1 more source
Role of Trypanosoma cruzi Trans-sialidase on the Escape from Host Immune Surveillance
Frontiers in Microbiology, 2016 Chagas disease is caused by the flagellate protozoan Trypanosoma cruzi, affecting millions of people throughout Latin America. The parasite dampens host immune response causing modifications in diverse lymphoid compartments, including the thymus.
A. F. F. R. Nardy +3 more
semanticscholar +1 more source
Unraveling the Differences of the Hydrolytic Activity of Trypanosoma cruzi trans-Sialidase and Trypanosoma rangeli Sialidase: A Quantum Mechanics–Molecular Mechanics Modeling Study [PDF]
, 2014 Chagas’ disease, also known as American trypanosomiasis, is a lethal, chronic disease that currently affects more than 10 million people in Central and South America. The trans-sialidase from Trypanosoma cruzi (T. cruzi, TcTS) is a crucial enzyme for the
Bueren Calabuig, Juan A. +2 more
core +1 more source
Molecular Ecology, EarlyView.ABSTRACT Parasites are expected to hybridise in similar ways to free‐living organisms, although this may be modified by their reduced genome architecture. Recombinant strains and taxa of hybrid origin can be studied in nature where hosts come into secondary contact. Here we apply genome‐wide analysis to parasites from a contact previously characterised
Jan Petružela +9 more
wiley +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2011 INTRODUCTION: For a long time, the importance of Chagas disease in Mexico, where many regarded it as an exotic malady, was questioned. Considering the great genetic diversity among isolates of Trypanosoma cruzi, the importance of this biological ...
César Gómez-Hernández +8 more
doaj
Potential geographic displacement of Chagas disease vectors under climate change
Medical and Veterinary Entomology, EarlyView.As a result of modelling the potential distribution of 55 triatomine species in the Neotropical region, with climate change projected for up to 2050, we found no significant changes. With climate change projected for up to 2080 in the Neotropical region, we see a significant potential for the migration of 55 species of triatomines towards the Amazon ...
Leandro Schlemmer Brasil +7 more
wiley +1 more source
Expert Review of Anti-Infective Therapy, 2015 Over the last 30 years, concomitant with successful transnational disease control programs across Latin America, Chagas disease has expanded from a neglected, endemic parasitic infection of the rural poor to an urbanized chronic disease, and now a ...
L. Messenger, M. Miles, C. Bern
semanticscholar +1 more source
Novel cruzain inhibitors for the treatment of Chagas' disease. [PDF]
, 2012 The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas' disease, affects millions of individuals and continues to be an important global health concern.
Arkin, Michelle R +6 more
core +1 more source
Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism
Obesity Reviews, EarlyView.ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso +5 more
wiley +1 more source
mBio, 2015 Trypanosoma cruzi is the etiologic agent of Chagas disease, and current methods for its genetic manipulation have been highly inefficient. We report here the use of the CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR ...
N. Lander +3 more
semanticscholar +1 more source