Trypanosoma musculi: Passive hemagglutination technique to measure antibody in mice
Experimental Parasitology, 1981Abstract A passive hemagglutination assay was developed to measure Trypanosoma musculi -specific antibody in mice. Indicator-erythrocyte donor mice received 550 rad 60 Co 24 hr before intraperitoneal injection of 3 × 10 4 T. musculi. T. musculi antigen-coated erythrocytes were obtained from these mice on Day 9 postinfection. T.
B O, Brooks, N D, Reed
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Enhanced Trypanosoma musculi infections in mice with concomitant malaria
Nature, 1975A PHASE of immunodepression is characteristic of experimental malaria infections and, in mice, immune responses to antigens as diverse as sheep red blood cells1, tetanus toxoid2, oncogenic viruses3 and Toxoplasma gondii4 are diminished. From immunological and epidemiological viewpoints it is important to know what happens when animals are infected with
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Trypanosoma musculi infection: depression of immune response to heterologous antigens
Canadian Journal of Microbiology, 1981The response to dinitrofluorobenzene (DNFB), bovine serum albumin (BSA), and sheep red blood cells (SRBC) was studied in CBA mice infected with Trypanosoma musculi at days ranging from 3 to 63 days of infection. DNFB contact sensitivity was normal.
M C, Lajeunesse, P, Viens
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The decline of immunological resistance of aging mice to Trypanosoma musculi
Mechanisms of Ageing and Development, 1982Aged mice of several strains studied developed much more severe infections of Trypanosoma musculi (mouse-specific parasite) than did young adults. Reduced resistance of the aged mice, assessed from the resistance conferred on irradiated recipients by transfer of normal and infected donor spleen cells, resulted from a much slower development of immunity
Albright, J W, Albright, J F
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Trypanosoma musculi: transfer of immunity from mother mice to litter
Canadian Journal of Microbiology, 1980Trypanosoma musculi infection in newborn and young CBA/J mice lasted longer and produced higher parasitemia than in adult mice. IgM, followed by IgG1 and IgG2 antibodies, appeared after 2 weeks following infection of 8-day-old mice. Baby mice that recovered from infection were immune.
S, Brenière, P, Viens
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Trypanosoma musculi: In vitro cultivation of blood forms in cell culture media
International Journal for Parasitology, 1977Abstract Blood forms of Trypanosoma musculi were grown at 37°C in media containing adherent peritoneal cells from normal or from T . musculi immune mice. Rat peritoneal cells and Hela cells supported growth equally well which was surprising in view of the strict mouse-host specificity of this parasite in vivo .
P, Viens +3 more
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Effects of Mesoionic Xanthine Analogs On Trypanosoma Musculi Development In Mice
Journal of Eukaryotic Microbiology, 1993ABSTRACT. Two derivatives of the mesoionic thiazolo[3,2‐a]pyrimidine‐5,7‐diones 1 were prepared and examined for in vivo antiprotozoan activity to study structure‐activity relationships that might lead us to more active derivatives. Mesoionic compounds 1A and 1B were inoculated into Swiss Webster male mice with Trypanosoma musculi infection.
D K, Sen, G O, Mbagwu, A, Adson
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Serological and vaccination studies with bloodstream and culture forms of Trypanosoma musculi
International Journal for Parasitology, 1982Abstract Khazindar S. H. and Dusanic D. G. 1982. Serological and vaccination studies with blood-stream and culture forms for Trypanosoma musculi . International Journal for Parasitology 12 : 257–264. Trypanosoma musculi bloodstream forms (BSF) were collected from immunosuppressed infected mice and extracted with phosphate buffered saline ...
S H, Khazindar, D G, Dusanic
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The role of the macrophage in immunity to Trypanosoma musculi
Parasite Immunology, 1986Summary Trypanosoma musculi was killed by adherent peritoneal exudate cells which had the typical appearance of macrophages. Observations by light and electron microscopy showed that the trypanosomes were phagocytozed and killed intracellular^ within phagocytic vacuoles of mouse macrophages. Adherence, phagocytosis and killing of T.
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The effect of cyclosporin A on Trypanosoma musculi infection of mice
Canadian Journal of Microbiology, 1988Cyclosporin A treatment of mice infected with Trypanosoma musculi mimicked the effect of T-cell deprivation in increasing the parasitemia and lowering the antibody responses. However, in contrast to T-cell deprivation, cyclosporin A treated mice were still able to clear the parasites from the blood.
M, Roger, P, Vigeant, P, Viens
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