Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire
PROTEOMICS, Volume 25, Issue 21-22, Page 253-276, November 2025.ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley +1 more source
Eristalis flower flies can be mechanical vectors of the common trypanosome bee parasite, Crithidia bombi [PDF]
, 2021 Abby E. Davis +9 more
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Journal of Experimental Medicine, 1923 1. In infections with Trypanosoma lewisi in the rat there are three manifestations of resistance against the parasite: (1) the retardation and final inhibition of reproduction of the trypanosomes by about the 10th day; (2) a sudden drop in the number of ...
W. H. Taliaferro
semanticscholar +1 more source
Standardization of bovine macrophage monolayers and isolation and culture of trypanosomes
Memorias do Instituto Oswaldo Cruz, 2003 We describe a method for culturing over 90% pure bovine macrophages from peripheral blood mononuclear cells separated with Nycoprep. The cells were cultured for 12 days and then stained with esterase and with anti CD14 to test for purity.
Omar A Saldarriaga +3 more
doaj +1 more source
Genome-wide analysis of 30 -untranslated regions supports the existence of post-transcriptional regulons controlling gene expression in trypanosomes [PDF]
, 2013 In eukaryotic cells, a group of messenger ribonucleic acids (mRNAs) encoding functionally interrelated proteins together with the trans-acting factors that coordinately modulate their expression is termed a post-transcriptional regulon, due to their ...
Agüero, Fernan Gonzalo +3 more
core +3 more sources
The Infection Rates of Trypanosomes in Squirrel Monkeys at Two Sites in the Brazilian Amazon
Memorias do Instituto Oswaldo Cruz, 1997 A study was conducted to determine the prevalence of natural infections by trypanosome species in squirrel monkeys: Saimiri sciureus (Linnaeus) and Saimiri ustus (Geoffroy) caught respectively near 2 hydroelectric plants: Balbina, in the State of ...
Mariangela Ziccardi +1 more
doaj +1 more source
Diversity in new flagellum tip attachment in bloodstream form African trypanosomes
, 2022 Laura Smithson +5 more
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Druggable Sterol Metabolizing Enzymes in Infectious Diseases: Cell Targets to Therapeutic Leads
BiomoleculesSterol biosynthesis via the mevalonate-isoprenoid pathway produces ergosterol (24β-methyl cholesta-5,7-dienol) necessary for growth in a wide-range of eukaryotic pathogenic organisms in eukaryotes, including the fungi, trypanosomes and amoebae, while ...
W. David Nes +2 more
doaj +1 more source
Comparative clinico-haematological analysis in young Zebu cattle experimentally infected with Trypanosoma vivax isolates from tsetse infested and non-tsetse infested areas of Northwest Ethiopia [PDF]
, 2015 Background: Ethiopia, particularly in the Northwest region, is affected by both tsetse and non-tsetse fly transmitted trypanosomosis, with significant impact on livestock productivity. The aim of this study was to determine and compare clinical findings
Abebe, Getachew +5 more
core +2 more sources
Frontiers in Microbiology, 2014 Tsetse flies (Glossina sp.) that transmit trypanosomes causing human (and animal) African trypanosomiasis (HAT and AAT, respectively) harbor symbiotic microorganisms, including the obligate primary symbiont Wigglesworthia glossinidia.
Illiassou eHamidou Soumana +3 more
doaj +1 more source