Results 41 to 50 of about 10,177 (210)

Immunodiagnosis of bovine trypanosomiasis in Anambra and Imo states, Nigeria, using enzyme-linked immunosorbent assay: zoonotic implications to human health [PDF]

Journal of Vector Borne Diseases, 2008
Background & objectives: The prevalence of trypanosomiasis was studied in cattle, being a major source of animal protein in Nigeria, thus, a very likely means of spread of Human African Trypano-somosis (HAT).
M.C. Ezeani, H. Okoro, V.O. Anosa, C.C. Onyenekwe, S.C. Meludu, C.E. Dioka, C.C. Azikiwe   +6 more
doaj  

The burden and spatial distribution of bovine African trypanosomes in small holder crop-livestock production systems in Tororo District, south-eastern Uganda

Parasites & Vectors, 2014
Background African animal trypanosomiasis (AAT) is considered to be one of the greatest constraints to livestock production and livestock-crop integration in most African countries.
Dennis Muhanguzi, Kim Picozzi, Jan Hattendorf, Michael Thrusfield, John David Kabasa, Charles Waiswa, Susan Christina Welburn   +6 more
doaj   +1 more source

Trypanosoma brucei brucei Induces Polymorphonuclear Neutrophil Activation and Neutrophil Extracellular Traps Release

Frontiers in Immunology, 2020
Trypanosoma brucei brucei trypomastigotes are classical blood parasites of cattle, these stages might become potential targets for circulating polymorphonuclear neutrophils (PMN).
Daniela Grob, Iván Conejeros, Zahady D. Velásquez, Christian Preußer, Ulrich Gärtner, Pablo Alarcón, Rafael A. Burgos, Carlos Hermosilla, Anja Taubert   +8 more
doaj   +1 more source

Pseudokinase NRP1 facilitates endocytosis of transferrin in the African trypanosome

Scientific Reports, 2022
Trypanosoma brucei causes human African trypanosomiasis (HAT) and nagana in cattle. During infection of a vertebrate, endocytosis of host transferrin (Tf) is important for viability of the parasite.
Gaurav Kumar, Bryanna Thomas, Kojo Mensa-Wilmot   +2 more
doaj   +1 more source

Spatially and genetically distinct African trypanosome virulence variants defined by host interferon-g response [PDF]

, 2007
We describe 2 spatially distinct foci of human African trypansomiasis in eastern Uganda. The Tororo and Soroti foci of <i>Trypanosoma brucei rhodesiense</i> infection were genetically distinct as characterized by 6 microsatellite and 1 ...
Anneli Cooper, Annette MacLeod, Bakhiet M, Bancroft GJ, Cattand P, Hertz CJ, Hunter CA, Jeremy M. Sternberg, Liam Morrison, Lindsay Sweeney, Lorna MacLean, Martin Odiit, Morrison LJ, Page RDM, Peter G. E. Kennedy, Schleifer KW, Schleifer KW, Sternberg JM, Woo PT, World Health Organization   +19 more
core   +1 more source

One Health – an Ecological and Evolutionary Framework for tackling Neglected Zoonotic Diseases [PDF]

, 2015
Understanding the complex population biology and transmission ecology of multihost parasites has been declared as one of the major challenges of biomedical sciences for the 21st century and the Neglected Zoonotic Diseases (NZDs) are perhaps the most ...
Adamo, Akopyants, Anderson, Antia, Azevedo, Berry, Betson, Biswas, Boatin, Boissier, Chargui, Civetello, Cleaveland, Combes, Consortium* THG, Crichton, Criscione, Cutillas, Delgado, Detwiler, Dobson, Doby, Dunams-Morel, Eberhard, Fan, Faye, Fenton, Fenton, Fraga de Azevedo, Funk, Garba, Gaunt, Gelanew, Genis, Gibbs, Gibson, Gouvras, Gretillat, Grigg, Gupta, Hahn, Hahn, Hanelt, Hargrove, Haydon, Hotez, Hotez, Huyse, Huyse, Inpankaew, Johnson, Jolles, Kaushik, Kaushik, Keesing, Kelly, Kilpatrick, King, Klepac, Koukounari, Lamberton, Laval, Le, Leger, Lembo, Liang, Liese, Lloyd-Smith, Lu, Lu, Lu, Lu, Lustigman, Machado, Maia, Mathews, Mavarez, Messenger, Messenger, Miles, Molyneux, Moné, Muhanguzi, Muller-Graf, Mupfasoni, Norton, Pardo-Diaz, Parrish, Pedersen, Perez-Quintero, Ramiro, Randolph, Ravel, Robinson, Rogers, Rollinson, Rudge, Rudge, Rudge, Salkeld, Saroufim, Silva Oliveira, Smith, Steinauer, Strauss, Streicker, Streicker, Sturm, Taylor, Theron, Theron, Tomley, UNDP, Viana, Volf, Wang, Webby, Webster, Webster, Webster, Webster, Webster, Webster, Welburn, Welburn, Whitlock, WHO, Wood, Woolhouse, Woolhouse, Woolhouse, Woolhouse, Woolhouse, Yamane, Yamane, Zhou   +135 more
core   +5 more sources

Ocorrência de Trypanosoma vivax no estado de Minas Gerais Occurrence of Trypanosoma vivax in Minas Gerais state, Brazil

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2008
A cow from Igarapé city, Minas Gerais state, Brazil, showing vision damage was referred at the Veterinary Hospital of the Universidade Federal de Minas Gerais.
A.U. Carvalho, D.C. Abrão, E.J. Facury Filho, P.R.O. Paes, M.F.B. Ribeiro   +4 more
doaj   +1 more source

Novel African trypanocidal agents: membrane rigidifying peptides [PDF]

, 2012
The bloodstream developmental forms of pathogenic African trypanosomes are uniquely susceptible to killing by small hydrophobic peptides. Trypanocidal activity is conferred by peptide hydrophobicity and charge distribution and results from increased ...
Andreas Hartel, Annette MacLeod, Chris Scelsi, John M. Harrington, Markus Engstler, Nicola G. Jones, Paul Capewell, Stephen Hajduk, Sylvie Bisser   +8 more
core   +3 more sources

Trypanosoma brucei methylthioadenosine phosphorylase protects the parasite from the antitrypanosomal effect of deoxyadenosine [PDF]

, 2016
Trypanosoma brucei causes African sleeping sickness for which no vaccine exists and available treatments are of limited use due to their high toxicity or lack of efficacy. T.
de Koning, Harry P., Hofer, Anders, Pavlova, Anna, Ranjbarian, Farahnaz, Vodnala, Munender   +4 more
core   +1 more source

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi, Martina Slapničková, Maryam Norouzbahari, Sarah D'Alessandro, Parham Foroumadi, Fariba Peytam, Federica Perego, Eva Doleželová, Zahra Emamgholipour, Maliheh Barazandeh Tehrani, Seyed Esmaeil Sadat‐Ebrahimi, Elahe Hosseinzadeh, Elmira Meghrazi Ahadi, Loghman Firoozpour, Hamidreza Bijanzadeh, Nicoletta Basilico, Alena Zíková, Alireza Foroumadi   +17 more
wiley   +1 more source