Targeting Kinetoplastid Parasites with ProTide Prodrugs: A Proof‐of‐Concept Study [PDF]
Neglected tropical diseases (NTDs) remain a major global health challenge, particularly in low‐ and middle‐income countries. Kinetoplastid parasites causing Chagas disease, leishmaniasis, and African trypanosomiasis rely on host purine salvage pathways, making nucleoside analogues attractive therapeutic candidates.
Silvester Lowe +6 more
wiley +2 more sources
Implemented strategic trypanosomosis and vector control activities along the Birbir River Basin through the application of deltamethrin-based insecticides using stationary attractive devices (targets), ground spraying, and live bait techniques [PDF]
Baseline and control intervention entomological and parasitological studies were conducted from September 2016 to February 2018 with the intended purpose of evaluating the effectiveness of implemented strategic trypanosomosis and vector control ...
Behablom Meharenet +3 more
doaj +2 more sources
Seasonal Dynamics and Associated Risk Factors of Bovine Trypanosomosis and Its Vector in Selected Districts of Gamo and Gofa Zones, Southern Ethiopia [PDF]
The median PCV of poor body‐conditioned animals is below 20 (anaemic) compared to corresponding body‐condition animals. Black‐ and red‐coloured animals are more significantly affected by trypanosomosis than white‐coloured animals. Multivariable logistic regression revealed more about contributory factors than univariable logistic regression.
Solomon Mekuria, Aschenaki Kalsa
wiley +2 more sources
A cross-sectional study involving a questionnaire, parasitological examination of cattle and entomological prospection were conducted in the Mezam Division of Cameroon from December 2013 to May 2014 in two seasons for the first time.
A. Mamoudou +5 more
semanticscholar +3 more sources
Trypanosoma brucei cattle infections contain cryptic transmission-adapted bloodstream forms at low parasitaemia [PDF]
Tsetse-transmitted Trypanosoma parasites infect a wide host range and cause Human African Trypanosomiasis and Animal African Trypanosomosis. The dominant hosts of Trypanosoma brucei sensu lato are non-human mammals, including agriculturally important ...
Stephen D. Larcombe +6 more
doaj +2 more sources
Camel Abortion Status in Iran- A Mini Review
About 180,000 old world camels (OWCs) including one-humped (Camelus Dromedarius) and two-humped (Camelus Bactrianus) camels (only 100–300 individuals) live in Iran.
Masoud Hassani
doaj +1 more source
Prevalence of trypanosomes associated with drug resistance in Shimba Hills, Kwale County, Kenya
Objective Animal African trypanosomiasis (AAT) is a life-threatening vector-borne disease, caused by trypanosome parasites, which are principally transmitted by tsetse flies.
Benard W. Kulohoma +5 more
doaj +1 more source
This report aims to discuss the occurrence of protozoan infestation in a Girolanda cattle herd in the state of Bahia / BA. Bovine trypanosomiasis is a severe disease that is harmful to cattle, inducing large productive and economic losses.
Felipe Gaia de Sousa +2 more
semanticscholar +1 more source
Improvements on Restricted Insecticide Application Protocol for Control of Human and Animal African Trypanosomiasis in Eastern Uganda [PDF]
African trypanosomes constrain livestock and human health in Sub-Saharan Africa, and aggravate poverty and hunger of these otherwise largely livestock-keeping communities. To solve this, there is need to develop and use effective and cheap tsetse control
Jan Hatendorf (651760) +28 more
core +1 more source
Focus–specific clinical profiles in human African trypanosomiasis caused by Trypanosoma brucei rhodesiense [PDF]
<p><b>Background:</b> Diverse clinical features have been reported in human African trypanosomiasis (HAT) foci caused by <i>Trypanosoma brucei rhodesiense</i> (<i>T.b.rhodesiense</i>) giving rise to the ...
Odiit, Martin +18 more
core +1 more source

