Occurrence and Public Health Implications of Brucella Abortus and Antimicrobial Residues in Raw Cow Milk in Bukombe District, Tanzania. [PDF]
Vet Med SciPoor husbandry practices in Bukombe District accelerate diseases in livestock and indiscriminate uses of antimicrobials. Cow abortions, raw cow placenta and aborted fetuses feeding dogs, communal grazing and watering and introduction of new animals predict brucellosis in the herd.
Mhozya M, Julius K M, Nonga HE.
europepmc +2 more sources
Targeting Kinetoplastid Parasites with ProTide Prodrugs: A Proof-of-Concept Study. [PDF]
ChemMedChemNeglected tropical diseases (NTDs) remain a major global health challenge, particularly in low‐ and middle‐income countries. Kinetoplastid parasites causing Chagas disease, leishmaniasis, and African trypanosomiasis rely on host purine salvage pathways, making nucleoside analogues attractive therapeutic candidates.
Lowe S +6 more
europepmc +2 more sources
Trypanotolerance Sheko cattle: an option for sustainable control of bovine trypanosomiasis
Open Veterinary Science, 2021 Trypanosomiasis is an impediment to cattle production and other agricultural development in tsetse-infested areas. It is a severe parasitic disease that causes loss in the production and performance of cattle.
Robi Dereje Tulu +2 more
doaj +1 more source
Molecular genotyping reveals mixed bovine and human trypanosomiasis in cattle from West Africa [PDF]
Veterinary World, 2023 Background and Aim: Animal trypanosomiasis is a major contributor to agricultural and economic losses, especially in sub-Saharan Africa. We have shown that some animal species expressed genes that are significant players in immune response to bovine ...
Olanrewaju B. Morenikeji +5 more
doaj +1 more source
Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection [PDF]
, 2020 Bovine African Trypanosomosis is an infectious parasitic disease affecting livestock productivity and thereby impairing the economic development of Sub-Saharan Africa. The most important trypanosome species implicated is T.
Brys, Lea +6 more
core +1 more source
Camel Abortion Status in Iran- A Mini Review
SVU-International Journal of Veterinary Sciences, 2021 About 180,000 old world camels (OWCs) including one-humped (Camelus Dromedarius) and two-humped (Camelus Bactrianus) camels (only 100–300 individuals) live in Iran.
Masoud Hassani
doaj +1 more source
Infections with extracellular trypanosomes require control by efficient innate immune mechanisms and can result in the destruction of the mammalian humoral immune system [PDF]
, 2020 Salivarian trypanosomes are extracellular parasites that affect humans, livestock, and game animals around the world. Through co-evolution with the mammalian immune system, trypanosomes have developed defense mechanisms that allow them to thrive in blood,
Magez, Stefan +3 more
core +1 more source
Trypanocidal and leishmanicidal activity of six limonoids [PDF]
, 2020 Six limonoids [kotschyienone A and B (1, 2), 7-deacetylgedunin (3), 7-deacetyl-7-oxogedunin (4), andirobin (5) and methyl angolensate (6)] were investigated for their trypanocidal and leishmanicidal activities using bloodstream forms of Trypanosoma ...
A-E Hay +30 more
core +3 more sources
MIF-mediated hemodilution promotes pathogenic anemia in experimental African trypanosomosis [PDF]
, 2016 Animal African trypanosomosis is a major threat to the economic development and human health in sub-Saharan Africa. Trypanosoma congolense infections represent the major constraint in livestock production, with anemia as the major pathogenic lethal ...
Beschin, Alain +17 more
core +10 more sources
Prevalence of trypanosomes associated with drug resistance in Shimba Hills, Kwale County, Kenya
BMC Research Notes, 2020 Objective Animal African trypanosomiasis (AAT) is a life-threatening vector-borne disease, caused by trypanosome parasites, which are principally transmitted by tsetse flies.
Benard W. Kulohoma +5 more
doaj +1 more source