Results 41 to 50 of about 2,146 (185)

Marker-assisted introgression of Trypanotolerance QTL in mice

open access: yesMammalian Genome, 2005
A marker-assisted introgression (MAI) experiment was conducted to use genetic markers to transfer each of the three trypanotolerance QTL from a donor mouse strain, C57BL/6, into a recipient mouse strain, A/J. We used a backcross strategy that consisted of selecting two lines, each carrying two of the donor QTL alleles through the backcross (BC) phase ...
Koudandé, O.D.   +2 more
openaire   +3 more sources

Note sur les limites de la trypanotolérance des bovins de race N'Dama ; observations faites en Guinée [PDF]

open access: yesTropicultura, 1983
A note on the observation made in Guinea concerning limitation of trypanotolerance in N'Dama cattle. An inquiry carried out in Guinea has revealed that the disappearance of trypanotolerance within some local N'Dama cattle can not be attributed to the ...
Demey, F., Bellver, M., Verhulst, A.
doaj  

High resolution mapping of trypanosomosis resistance loci Tir2 and Tir3 using F12 advanced intercross lines with major locus Tir1 fixed for the susceptible allele

open access: yesBMC Genomics, 2010
Background Trypanosomosis is the most economically important disease constraint to livestock productivity in Africa. A number of trypanotolerant cattle breeds are found in West Africa, and identification of the genes conferring trypanotolerance could ...
Soller Morris   +2 more
doaj   +1 more source

MIF contributes to Trypanosoma brucei associated immunopathogenicity development [PDF]

open access: yes, 2014
African trypanosomiasis is a chronic debilitating disease affecting the health and economic well-being of many people in developing countries. The pathogenicity associated with this disease involves a persistent inflammatory response, whereby M1-type ...
Beschin, Alain   +11 more
core   +9 more sources

Programmes de sélection du bovin N’Dama en Afrique de l’Ouest : cas du Sénégal, du Mali et de la Gambie

open access: yesCahiers Agricultures, 2020
La sélection génétique est un moyen pour augmenter la productivité des races endémiques dans des environnements hostiles. La trypanotolérance du bovin N’Dama a été l’argument central de la mise en œuvre des programmes de sélection de cette race en Gambie,
Camara Younouss   +4 more
doaj   +1 more source

The performance of Orma Boran and Maasai Zebu crossbreeds in a trypanosomosis endemic area of Nguruman, south western Kenya

open access: yesOnderstepoort Journal of Veterinary Research, 2005
Studies on the trypanotolerance of Orma Boran X Maasai Zebu (Orma Zebu) crossbred cattle (F1 progeny) and pure-bred Maasai Zebu contemporaries were carried out in Nguruman, south western Kenya. The two groups were monitored from birth for a period of 2
M.W. Maichomo   +3 more
doaj   +1 more source

Iron Homeostasis and Trypanosoma brucei Associated Immunopathogenicity Development: A Battle/Quest for Iron

open access: yesBioMed Research International, Volume 2015, Issue 1, 2015., 2015
African trypanosomosis is a chronic debilitating disease affecting the health and economic well‐being of developing countries. The immune response during African trypanosome infection consisting of a strong proinflammatory M1‐type activation of the myeloid phagocyte system (MYPS) results in iron deprivation for these extracellular parasites.
Benoit Stijlemans   +5 more
wiley   +1 more source

Host Susceptibility to African Trypanosomiasis: Trypanotolerance

open access: yes, 1982
Publisher Summary The exploitation of genetic resistance to disease is an important consideration in livestock development programs, where conventional disease control measures are not effective or are too costly. Such an approach may be directly applicable to African animal trypanosomiasis.
Murray, M.   +2 more
openaire   +3 more sources

Comparative genome analysis of trypanotolerance QTL

open access: yesVeterinary Immunology and Immunopathology, 2009
Certain breeds of domestic ruminants show remarkable resistance to the effects of African trypanosomosis. Unlike susceptible animals, trypanotolerant animals control parasitemia and do not showsevere anaemia or production loss. Identification of trypanotolerance genes in cattle is hampered by cost and breeding time.
Ng'ang'a, J., Imbuga, M., Iraqi, F.A.
openaire   +3 more sources

Expression of trypanotolerance in N’Dama x Boran crosses under field challenge in relation to N’Dama genome content

open access: yesBMC Proceedings, 2011
Background Animal trypanosomosis in sub-Saharan Africa is a major obstacle to livestock based agriculture. Control relies on drugs with increasing incidence of multiple-drug resistance.
Orenge Caleb   +7 more
doaj   +1 more source

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