Immunoproteomic Identification and Vaccine Assessment of Trypanosoma vivax Invariant Surface Glycoprotein [PDF]
Background: African animal trypanosomosis, caused by Trypanosoma vivax, remains a significant challenge to cattle health and productivity in regions where it is endemic. The development of vaccines against this parasite is particularly challenging due to
Genaro Francisco Díaz +4 more
doaj +2 more sources
Knowledge, Attitudes, and Practices of Small Ruminant and Pig Farmers Regarding Tsetse Flies and Animal African Trypanosomosis in Southern Benin [PDF]
Background Animal African trypanosomosis (AAT) remains a major constraint to livestock production across sub‐Saharan Africa despite ongoing control efforts. Although several studies have assessed farmers’ knowledge, attitudes, and practices (KAP) regarding AAT in cattle production systems, little is known about small ruminant and pig farmers ...
Zul-Kifl Affolabi +13 more
wiley +2 more sources
Integrative Genomics Identifies Candidate Genes Underlying Trypanotolerance in Hybrid African Cattle [PDF]
Integrative genomics combines data from different omics sources to link genotypes and phenotypes with the aim of unravelling biological networks and pathways that undergird complex traits, particularly with respect to disease.
Gillian P. McHugo +10 more
doaj +2 more sources
Understanding Bovine Trypanosomiasis and Trypanotolerance: The Promise of Functional Genomics
African bovine trypanosomiasis, caused by the protozoan parasite Trypanosoma congolense, is endemic throughout sub-Saharan Africa and is a major constraint on livestock production. A promising approach to disease control is to understand and exploit naturally evolved trypanotolerance.
Paul Coussens +2 more
exaly +4 more sources
Identifying Cattle Breed-Specific Partner Choice of Transcription Factors during the African Trypanosomiasis Disease Progression Using Bioinformatics Analysis [PDF]
African Animal Trypanosomiasis (AAT) is a disease caused by pathogenic trypanosomes which affects millions of livestock every year causing huge economic losses in agricultural production especially in sub-Saharan Africa.
Abirami Rajavel +3 more
doaj +2 more sources
Evaluation of a Field Test for Trypanotolerance in Young N'Dama Cattle
In three separate tests in 1987, 1988 and 1989, a total of 436 one-year-old N'Dama cattle were maintained for 12, 18 and 24 weeks under a medium natural tsetse-trypanosome challenge in Gabon, Central Africa. Matching health and performance data were recorded on 4, 10 and 13 occasions respectively, to allow simultaneous evaluation of the effect of ...
J C M Trail +2 more
exaly +4 more sources
Background Trypanosomosis, a protozoal disease affecting livestock, transmitted by Glossina (tsetse) flies is a major constraint to agricultural production in Sub-Saharan Africa. It is accepted that utilization of the native trypanotolerance exhibited in
Orenge Caleb O +7 more
doaj +2 more sources
African Trypanosomiasis Research at a Crossroads: Bibliometric and Systematic Insights for the Future [PDF]
Aim Despite a reduction in the overall incidence and prevalence in the last two decades, trypanosomiasis continues to be a public health concern in Africa. This study was designed to comprehensively evaluate current trends in trypanosomiasis research using bibliometric approaches to uncover emerging topics and knowledge gaps, thereby guiding future ...
Israel Ogwuche Ogra +8 more
wiley +2 more sources
Expression of trypanotolerance in N’Dama x Boran crosses under field challenge in relation to N’Dama genome content [PDF]
Background Animal trypanosomosis in sub-Saharan Africa is a major obstacle to livestock based agriculture. Control relies on drugs with increasing incidence of multiple-drug resistance.
Orenge Caleb +7 more
doaj +2 more sources
Trypanotolerance and the value of conserving livestock genetic resources
Studies have been made in two main areas of genetic research on African trypanotolerant (N'Dama) cattle. The first is of the significance for performance and the heritability of trypanotolerance traits and the second is the search for markers of the breed type and the traits of interest.
Trail, J.C.M. +2 more
openaire +4 more sources

