Results 1 to 10 of about 2,661 (179)

A gene expression comparison of Trypanosoma brucei and Trypanosoma congolense in the bloodstream of the mammalian host reveals species-specific adaptations to density-dependent development [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2018
In the bloodstream of mammalian hosts Trypanosoma brucei undergoes well-characterised density-dependent growth control and developmental adaptation for transmission. This involves the differentiation from proliferative, morphologically 'slender' forms to
Eleanor Silvester   +2 more
exaly   +2 more sources

Route of inoculation influences Trypanosoma congolense and Trypanosoma brucei brucei virulence in Swiss white mice. [PDF]

open access: yesPLoS ONE, 2019
Experiments on infections caused by trypanosomes are widely performed in Swiss white mice through various inoculation routes. To better understand the effect of route of trypanosome inoculation on disease outcomes in this model, we characterised the ...
Kariuki Ndungu   +8 more
doaj   +2 more sources

Comparative chromatin analysis of Trypanosoma congolense [PDF]

open access: yesMemorias do Instituto Oswaldo Cruz, 1994
The chromatin of Trypanosoma congolense was analyzed by electron microscopy. The chromatin is organized as nucleosome filaments but does not form a 30 nm fiber. There are five groups of histones, including a histone H1-like protein, which has a molecular
Wolfram Schlimme   +3 more
doaj   +5 more sources

TLR-2 and MyD88-Dependent Activation of MAPK and STAT Proteins Regulates Proinflammatory Cytokine Response and Immunity to Experimental Trypanosoma congolense Infection [PDF]

open access: yesFrontiers in Immunology, 2019
It is known that Trypanosoma congolense infection in mice is associated with increased production of proinflammatory cytokines by macrophages and monocytes.
Shiby Kuriakose   +5 more
doaj   +2 more sources

Refractory hypoglycaemia in a dog infected with Trypanosoma congolense [PDF]

open access: yesParasite, 2016
A 20 kg German shepherd dog was presented to a French veterinary teaching hospital for seizures and hyperthermia. The dog had returned 1 month previously from a six-month stay in Senegal and sub-Saharan Africa.
Deschamps Jack-Yves   +7 more
doaj   +2 more sources

Development of Cathepsin L-like Real-Time PCR Assays for the Detection of African Animal Trypanosomosis (AAT) in South Africa

open access: yesPathogens, 2022
African animal trypanosomosis (AAT), is an infectious parasitic disease of wildlife and livestock caused by multiple species and strains of Trypanosoma.
Samantha Mnkandla   +3 more
doaj   +1 more source

Tsetse Flies Infected with Trypanosomes in Three Active Human African Trypanosomiasis Foci of the Republic of Congo

open access: yesPathogens, 2022
Introduction: Human African trypanosomiasis (HAT) is a neglected tropical disease still endemic in the Republic of Congo. Despite the continuous detection of HAT cases in the country, there is still not enough data on trypanosome infections in tsetse ...
Irina Bemba   +3 more
doaj   +1 more source

The Antiprotozoal Activity of Papua New Guinea Propolis and Its Triterpenes

open access: yesMolecules, 2022
Profiling a propolis sample from Papua New Guinea (PNG) using high-resolution mass spectrometry indicated that it contained several triterpenoids. Further fractionation by column chromatography and medium-pressure liquid chromatography (MPLC) followed by
Samya S. Alenezi   +10 more
doaj   +1 more source

The individual components of commercial isometamidium do not possess stronger trypanocidal activity than the mixture, nor bypass isometamidium resistance

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2019
The four components present in the trypanocidal treatment Samorin, the commercially available formulation of isometamidium, were separated and purified by column chromatography.
Anthonius A. Eze   +4 more
doaj   +1 more source

Les glossines de l'agglomération brazzavilloise. III. Rôle vecteur dans les trypanosomoses animales et humaine

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1987
Depuis l'élimination en 1985 des glossines du centre ville de la capitale congolaise, la trypanosomose animale à trypanosoma congolense y a totalement disparu. Cependant, en périphérie Sud de Brazzaville parallélement à l'épizootie à t.
F. Noireau   +5 more
doaj   +1 more source

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