The interaction ofTrypanosoma congolensewith endothelial cells [PDF]
Factors which affect adhesion of culturedTrypanosoma congolensebloodstream forms to mammalian feeder cells have been examined. Using anin vitrobinding assay, the initial events following interaction of trypanosomes with bovine aorta endothelial (BAE) cells were monitored by both light- and electron microscopy.
Hemphill A, Frame I, Ross CA
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Proteomic Selection of Immunodiagnostic Antigens for Trypanosoma congolense [PDF]
Animal African Trypanosomosis (AAT) presents a severe problem for agricultural development in sub-Saharan Africa. It is caused by several trypanosome species and current means of diagnosis are expensive and impractical for field use. Our aim was to discover antigens for the detection of antibodies to Trypanosoma congolense, one of the main causative ...
Fleming, Jennifer R. +5 more
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Comparative chromatin analysis of Trypanosoma congolense [PDF]
The chromatin of Trypanosoma congolense was analyzed by electron microscopy. The chromatin is organized as nucleosome filaments but does not form a 30 nm fiber. There are five groups of histones, including a histone H1-like protein, which has a molecular
Wolfram Schlimme +3 more
doaj +5 more sources
A multigene family encoding surface glycoproteins in Trypanosoma congolense [PDF]
Trypanosoma congolense, the causative agent of the most important livestock disease in Africa, expresses specific surface proteins involved in its parasitic lifestyle. Unfortunately, the complete repertoire of such molecules is far from being deciphered.
Magali Thonnus +2 more
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Recherches sur la biologie de Trypanosoma congolense Broden 1904. II. Isolement et entretien de souches "sauvages" sur milieu de culture monophasique solide au sang total de zébu [PDF]
L'auteur propose la préparation et l'emploi d'un milieu gélosé contenant 15 p. 100 de sang total de veau zébu. Il s'agit essentiellement d'une phase solide sur laquelle un artifice de manipulation permet d'entretenir Trypanosoma congolense. Ce milieu est
Jean-Pierre Berson
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Antitrypanosomal Activity and Molecular Docking Studies of Lobetyolin From <i>Lobelia rhynchopetalum</i> Hemsl. Root Extract Against <i>Trypanosoma congolense</i> Field Isolates. [PDF]
Currently available drugs for trypanosomiasis are few, and their use is limited by toxicity and growing resistance. This highlights the need for safer and more effective alternatives. In this study, the in vitro and in vivo antitrypanosomal activities of an 80% methanol root extract of Lobelia rhynchopetalum and its major constituent were evaluated ...
Yimer S +4 more
europepmc +2 more sources
Mechanisms controlling anaemia in Trypanosoma congolense infected mice. [PDF]
Trypanosoma congolense are extracellular protozoan parasites of the blood stream of artiodactyls and are one of the main constraints on cattle production in Africa.
de Angelis Martin Hrabé +66 more
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Mycophenolic acid and its derivatives as potential chemotherapeutic agents targeting inosine monophosphate dehydrogenase in Trypanosoma congolense [PDF]
application/pdfThis study aimed to evaluate the trypanocidal activity of mycophenolic acid (MPA) and its derivatives for Trypanosoma congolense. The proliferation of T. congolense was completely inhibited by adding
Jąkalski, Marcin +12 more
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Discovery of mating in the major African livestock pathogen Trypanosoma congolense [PDF]
The protozoan parasite, Trypanosoma congolense, is one of the most economically important pathogens of livestock in Africa and, through its impact on cattle health and productivity, has a significant effect on human health and well being.
Alana Black +40 more
core +1 more source
Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species [PDF]
Antigenic variation enables pathogens to avoid the host immune response by continual switching of surface proteins. The protozoan blood parasite Trypanosoma brucei causes human African trypanosomiasis ("sleeping sickness") across sub-Saharan Africa and ...
Browne, H. +57 more
core +1 more source

