Results 11 to 20 of about 2,661 (179)

Antitrypanosomal Activity and Molecular Docking Studies of Lobetyolin From <i>Lobelia rhynchopetalum</i> Hemsl. Root Extract Against <i>Trypanosoma congolense</i> Field Isolates. [PDF]

Biomed Res Int
Currently available drugs for trypanosomiasis are few, and their use is limited by toxicity and growing resistance. This highlights the need for safer and more effective alternatives. In this study, the in vitro and in vivo antitrypanosomal activities of an 80% methanol root extract of Lobelia rhynchopetalum and its major constituent were evaluated ...
Yimer S, Tewelde E, Bisrat D, Tadesse S, Yeshak MY.   +4 more
europepmc   +2 more sources

An alternative approach to detect Trypanosoma in Glossina (Diptera: Glossinidae) without dissection

Journal of Infection in Developing Countries, 2008
Background: Determining if a tsetse fly is infected by trypanosomes and thus potentially able to transmit trypanosome-related human and animal diseases is an extremely laborious and time-consuming task to perform, especially under field conditions.
Filipa Ferreira,1 Jorge Cano,2 Andreia Furtado,3 Nicolas Ndong-Mabale,4 Pedro Ndong-Asumu,4 Agustin Benito,2 João Pinto,3 Maria Odete Afonso,5 Jorge Seixas,1 Jorge Atouguia,1 Sónia Centeno-Lima.1
doaj   +3 more sources

Résistance médicamenteuse d'isolats récents de Trypanosoma brucei et Trypanosoma congolense

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1988
Des études ont été menées sur des souris pour déterminer la sensibilité aux médicaments d’isolats récents de Trypanosoma brucei et Trypanosoma congolense. Chacune des onze souches de T. congolense et des cinq souches de T. brucei, toutes isolées sur des
R.A. Joshua
doaj   +1 more source

Population genetics of forest type of Trypanosoma congolense circulating in Glossina palpalis palpalis of Fontem in the South-West region of Cameroon

Parasites & Vectors, 2014
Background Genetic variation of microsatellite loci is a widely used method for the analysis of population genetic structure of several organisms. To improve our knowledge on the population genetics of trypanosomes, Trypanosoma congolense forest and ...
Gustave Simo, Pythagore Soubgwi Fogue, Tresor Tito Tanekou Melachio, Flobert Njiokou, Jules Roger Kuiate, Tazoacha Asonganyi   +5 more
doaj   +1 more source

Recherches sur la biologie de Trypanosoma congolense Broden 1904. II. Isolement et entretien de souches "sauvages" sur milieu de culture monophasique solide au sang total de zébu

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1967
L'auteur propose la préparation et l'emploi d'un milieu gélosé contenant 15 p. 100 de sang total de veau zébu. Il s'agit essentiellement d'une phase solide sur laquelle un artifice de manipulation permet d'entretenir Trypanosoma congolense. Ce milieu est
Jean-Pierre Berson
doaj   +1 more source

The interaction ofTrypanosoma congolensewith endothelial cells [PDF]

Parasitology, 1994
Factors which affect adhesion of culturedTrypanosoma congolensebloodstream forms to mammalian feeder cells have been examined. Using anin vitrobinding assay, the initial events following interaction of trypanosomes with bovine aorta endothelial (BAE) cells were monitored by both light- and electron microscopy.
Hemphill A, Frame I, Ross CA
openaire   +3 more sources

Isothermal microcalorimetry – A quantitative method to monitor Trypanosoma congolense growth and growth inhibition by trypanocidal drugs in real time

International Journal for Parasitology: Drugs and Drug Resistance, 2018
Trypanosoma congolense is a protozoan parasite that is transmitted by tsetse flies, causing African Animal Trypanosomiasis, also known as Nagana, in sub-Saharan Africa. Nagana is a fatal disease of livestock that causes severe economic losses.
M. Gysin, O. Braissant, K. Gillingwater, R. Brun, P. Mäser, T. Wenzler   +5 more
doaj   +1 more source

Epidemiology of Trypanosomiasis in Wildlife—Implications for Humans at the Wildlife Interface in Africa

Frontiers in Veterinary Science, 2021
While both human and animal trypanosomiasis continue to present as major human and animal public health constraints globally, detailed analyses of trypanosome wildlife reservoir hosts remain sparse.
Keneth Iceland Kasozi, Keneth Iceland Kasozi, Gerald Zirintunda, Fred Ssempijja, Bridget Buyinza, Khalid J. Alzahrani, Kevin Matama, Helen N. Nakimbugwe, Helen N. Nakimbugwe, Luay Alkazmi, David Onanyang, Paul Bogere, Juma John Ochieng, Saher Islam, Wycliff Matovu, David Paul Nalumenya, Gaber El-Saber Batiha, Lawrence Obado Osuwat, Mahmoud Abdelhamid, Tianren Shen, Tianren Shen, Leonard Omadang, Susan Christina Welburn, Susan Christina Welburn   +23 more
doaj   +1 more source

Epidemiological study of canine Trypanosomosis in an urban area of Ivory coast

Parasite, 2009
Following confirmed cases of trypanosomosis in military working dogs, a cross-sectional study was undertaken to evaluate the source of infection and determine the prevalence of canine infection with Trypanosoma congolense in the urban focus of Abidjan ...
Keck N., Herder S., Kaba D., Solano P., Gomez J., Cuny G., Davoust B.   +6 more
doaj   +1 more source

Identification of different trypanosome species in the mid-guts of tsetse flies of the Malanga (Kimpese) sleeping sickness focus of the Democratic Republic of Congo

Parasites & Vectors, 2012
Background The Malanga sleeping sickness focus of the Democratic Republic of Congo has shown an epidemic evolution of disease during the last century. However, following case detection and treatment, the prevalence of the disease decreased considerably ...
Simo Gustave, Silatsa Barberine, Flobert Njiokou, Lutumba Pascal, Mansinsa Philemon, Madinga Joule, Manzambi Emile, De Deken Reginald, Asonganyi Tazoacha   +8 more
doaj   +1 more source