Results 41 to 50 of about 52,969 (219)

Influence de l’infection à Trypanosoma congolense sur quelques constituants protéiques et inorganiques du sang chez le mouton

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1996
Cette étude avait pour objet d'évaluer les variations des concentrations plasmatiques de zinc, cuivre, calcium, magnésium, phosphate inorganique, protéines totales, albumine et globuline, de la sidérémie, ainsi que la capacité de fixation du fer chez des
E. Katunguka Rwakishaya
doaj   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, Volume 7, Issue 5, October 2026.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Trypanosome parasite (Trypanosoma congolense (strain ICIPE 002)) concentration in dissected Tsetse flies (Glossina fuscipes fuscipes) midgut

, 2017
Trypanosome parasite (Trypanosoma congolense (strain ICIPE 002)) concentration in dissected Tsetse flies (Glossina fuscipes fuscipes ...
Adly M M Abd-alla (8054159), Shem J Ochieng (8054171), Ekesi, Sunday, Sevgan Subramanian (8014463), Nguya Kalemba Maniania (8054174), Samuel O Odiwuor (8054168), Komivi Senyo Akutse (8054165), Ochieng, Shem J, Fathiya M Khamis (7883699), Subramanian, Sevgan, Maniania, Nguya Kalemba, Sunday Ekesi (307651), Wamiti, Lawrence G, Khamis, Fathiya Mbarak, Lawrence G Wamiti (8054156), Abd-alla, Adly M M, Odiwuor, Samuel O, Fidelis L O Ombura (8054162), Ombura, Fidelis L O, Akutse, Komivi Senyo   +19 more
core   +1 more source

Beyond the Active Site: First‐In‐Class Leishmania Infantum Trypanothione Reductase Dimerization Disruptors as Antileishmanial Leads

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
This review outlines a pioneering strategy to inhibit Leishmania infantum trypanothione reductase by disrupting its dimer interface. From peptides to small‐molecule proteomimetics, multiple chemotypes achieved potent enzymatic inhibition and notable cellular antileishmanial activity, highlighting a new therapeutic paradigm.
María‐José Camarasa, Miguel Maldonado, Alvaro de la Cruz‐Potenciano, Sonia de Castro   +3 more
wiley   +1 more source

In vitro Anti-trypanosomal Activity of Ethanolic and n-Hexane Extracts of Hymenocardia acida Stem Bark against Trypanosoma brucei brucei and Trypanosoma congolense

UMYU Journal of Microbiology Research
The development of resistance by trypanosomes to existing trypanocidal drugs necessitates the need to search for safer and more effective alternative drugs with a broad spectrum of activity.
Lawal, S. M., Inabo, H. I., Ella, E. E., Okubanjo, O. O.   +3 more
doaj   +1 more source

Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor

eLife, 2016
The haptoglobin-haemoglobin receptor of the African trypanosome species, Trypanosoma brucei, is expressed when the parasite is in the bloodstream of the mammalian host, allowing it to acquire haem through the uptake of haptoglobin-haemoglobin complexes ...
Harriet Lane-Serff, Paula MacGregor, Lori Peacock, Olivia JS Macleod, Christopher Kay, Wendy Gibson, Matthew K Higgins, Mark Carrington   +7 more
doaj   +1 more source

Frequency and diversity of trypanosomes in sheep and goats from Mongo County in South Gabon, Central Africa [PDF]

Veterinary World, 2020
Background and Aim: Trypanosomosis is a major impediment to livestock farming in sub-Saharan Africa. It is a vector-borne disease caused by several species of protozoan parasites, namely, trypanosomes. The present study aimed to identify the diversity of
Gael Darren Maganga, Larson Boundenga, Emmanuella Jacqueline Ologui-Minkue-Edzo, Linda Bohou Kombila, Telstar Ghestin Ndong Mebaley, Brice Kumulungui, Jacques François Mavoungou   +6 more
doaj   +1 more source

Comparative evaluation of the attractiveness of new polyethylene screens versus West African tiny target for the control of tsetse flies

Medical and Veterinary Entomology, Volume 40, Issue 3, Page 489-497, September 2026.
The material has no significant difference in captures (non‐shiny cotton‐polyester screens vs. the shiny polyethylene screens), but the vertical screen attracted significantly more G. tachinoides for each type of material. Full white horizontal screen was significantly lower than the reference WATT.
Ernest Wendemanegde Salou, Geoffrey Gimonneau, Wilfrid Yoni, Issiaka Barry, Viral Shah, Marc Desquesnes   +5 more
wiley   +1 more source

Probing 5‐Nitroimidazole‐Triazole Hybrids as Potential Anti‐Kinetoplastid Agents: Synthesis and In Vitro Efficacy

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
A series of 5‐nitroimidazole‐1,2,3‐triazole hybrids was synthesised and evaluated for antitrypanosomatid activity to assess their potential as treatments against leishmaniasis and trypanosomiasis. No notable in vitro activity against Leishmania was detected.
Liandi Ferreira, Gideon D. Badenhorst, Janine Aucamp, Keisuke Suganuma, David D. N’Da   +4 more
wiley   +1 more source

Trypanosoma congolense trans-sialidase sequence similarities expressed as percentage of identical amino acids in pair-wise alignments.

, 2013
Tcon = Trypanosoma ...
Gloria D. Chechet (493602), Sørge Kelm (72288), Joel Smith (493601), Frank Dietz (72284), Mario Waespy (493599), Thaddeus T. Gbem (493598), Bettina Hesse (493600), Jonathan A. Nok (493603)   +7 more
core   +1 more source