Results 51 to 60 of about 2,661 (179)

Equine trypanosomiasis, a systematic review and meta‐analyses: Prevalence, morbidity and mortality

Equine Veterinary Journal, Volume 58, Issue 2, Page 291-319, March 2026.
Abstract Background Equine trypanosomiasis is a neglected protozoal disease. Objectives To perform a systematic search of literature to explore: (1) In equines what is the global geographical distribution and prevalence of trypanosomiasis? In low and middle‐income countries (LMICs) is trypanosomiasis more prevalent than in higher‐income countries (HICs)
Alexandra G. Raftery, Lauren Gummery, Karelhia Garcia, Dinesh Mohite, Paul Capewell, David G. M. Sutton   +5 more
wiley   +1 more source

Cytotoxicity and Antimicrobial Activity of GaMF1 Analogs

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
GaMF1 is a reported, highly potent inhibitor of mycobacterial ATP synthase. Structural modification of this scaffold significantly changes biological activity. We present GaMF1 analogues with strong antiparasitic effects, potential antiproliferative properties, and discuss the selectivity limitations of the parent compound and its analogues.
Jan Chasák, Petr Vyvlečka, Ivan Nemec, An Matheeussen, Natascha Van Pelt, Paul Cos, Guy Caljon, Vladimír Kryštof, Lucie Brulíková   +8 more
wiley   +1 more source

The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa

The FEBS Journal, Volume 293, Issue 4, Page 948-958, February 2026.
Metacaspases are Ca2+‐dependent cysteine proteases whose structural characteristics, particularly calcium binding and autocatalytic processing, govern their activation and biological functions. These enzymes differ among microorganisms and regulate their cell cycles, making them excellent targets for drug development.
Ane C. M. Duarte, Mariana N. R. Trujilho, Karolaine S. S. M. Valdivia, Aline F. Araujo, Laura M. C. de Lorena, Vinicius H. de Oliveira, Beatriz V. Pereira, Emilly R. Leme, Wagner A. S. Júdice, Maurício F. M. Machado   +9 more
wiley   +1 more source

Biométrie, morphologie et virulence de Trypanosoma (Nannomonas) congolense à travers 640 passages sur souris en 10 ans

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1976
Trois souches de Trypanosoma congolense ont été récoltées en 1964 dans le Sud-Ouest du Sénégal et l'une d'elles passée sur souris pendant plus de 10 ans. Les trois souches présentent la variation Dimorphon.
Saydil Touré
doaj   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, Volume 301, Issue 2, Page 280-329, February 2026.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Prévalence trypanosomienne dans le bassin cotonnier en zone soudanaise de Côte d’Ivoire

Revue Marocaine des Sciences Agronomiques et Vétérinaires, 2020
La prévalence trypanosomienne a été évaluée dans les cheptels du bassin cotonnier en zone soudanaise de Côte d’Ivoire. Les prélèvements de sang ont été effectués du 22 avril au 21 mai 2016, sur 582 bovins dont 374 mâles et 195 femelles, appartenant aux ...
Loukou Séverin YAO, Biégo Guillaume GRAGNON, Kouakou Louis N’DRI, Bamoro COULIBALY, David KOMONO   +4 more
doaj  

Cinétique de la mort in vitro de Trypanosoma vivax et Trypanosoma congolense Vanderplank au contact de médicaments trypanocides

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1967
Trypanosoma vivax et Trypanosoma congolense ont été soumis in vitro à l'action de trypanocides appartenant à trois familles chimiques: diamidine, quinoléine et phénanthridine.
Saydil Touré
doaj   +1 more source

Seasonal Dynamics and Associated Risk Factors of Bovine Trypanosomosis and Its Vector in Selected Districts of Gamo and Gofa Zones, Southern Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
The median PCV of poor body‐conditioned animals is below 20 (anaemic) compared to corresponding body‐condition animals. Black‐ and red‐coloured animals are more significantly affected by trypanosomosis than white‐coloured animals. Multivariable logistic regression revealed more about contributory factors than univariable logistic regression.
Solomon Mekuria, Aschenaki Kalsa
wiley   +1 more source

Virulence of Trypanosoma congolense strains isolated from cattle and African buffaloes (Syncerus caffer) in KwaZulu-Natal, South Africa

Onderstepoort Journal of Veterinary Research, 2014
Trypanosoma congolense and Trypanosoma vivax are major species that infect cattle in north-eastern KwaZulu-Natal (KZN), South Africa. Of the two genetically distinct types of T.
Makhosazana Y. Motloang, Justin Masumu, Ben J. Mans, Abdalla A. Latif   +3 more
doaj   +1 more source

The Dual Role of the 16mer Motif Within the 3′ Untranslated Region of the Variant Surface Glycoprotein of Trypanosoma brucei

Molecular Microbiology, Volume 125, Issue 1, Page 67-79, January 2026.
A fully conserved 16mer motif is required in the silent VSG to trigger efficient silencing of the expression site (ES)‐resident VSG and a successful exchange of the VSG coat. ABSTRACT The variant surface glycoprotein (VSG) of African trypanosomes is essential for the survival of bloodstream form parasites.
Majeed Bakari‐Soale, Christopher Batram, Henriette Zimmermann, Nicola G. Jones, Markus Engstler   +4 more
wiley   +1 more source