Results 61 to 70 of about 52,969 (219)
Archiv der Pharmazie, Volume 359, Issue 3, March 2026.In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi +17 more
wiley +1 more source
Haematological changes in Wistar rats experimentally infected with Trypanosoma congolense and Trypanosoma brucei brucei obtained from North-west Nigeria [PDF]
, 2021 This study determined haematological changes in Wistar rats experimentally infected with local strains of Trypanosoma congolense and Trypanosoma brucei brucei. Forty-five Wistar rats between 10 – 12 weeks old weighing between 210 – 240 g were used.
Fajinmi, A.O. +17 more
core +1 more source
Equine trypanosomiasis, a systematic review: Disease management
Equine Veterinary Journal, Volume 58, Issue 2, Page 320-332, March 2026.Abstract Background Equine trypanosomiasis is a neglected protozoal disease. Objectives To answer the study question: In equines what are the effects of disease management of trypanosomiasis on disease severity (individual level) and disease prevalence (population level) compared to no intervention? Study Design Systematic review.
Alexandra G. Raftery +5 more
wiley +1 more source
Interference in the Establishment of Superinfections with Trypanosoma congolense in Cattle
The Journal of Parasitology, 1982 To examine the influence of an established infection on subsequent challenge with another unrelated trypanosome serodeme, cattle were subjected to two challenges, 5 to 6 wk apart, with unrelated isolates of Trypanosoma congolense. The primary infection inhibited the establishment of the second infection despite the initial absence of detectable ...
Morrison, W. Ivan +4 more
openaire +2 more sources
WIREs RNA, Volume 17, Issue 2, March/April 2026.U‐indel RNA editing targets mRNA:gRNA duplexes through three key complexes that collectively govern assembly, specificity, catalysis, and developmental regulation. Modern tools, including artificial intelligence, analyze the organization, dynamics, and evolution of the remarkable holo‐editosome, opening new avenues in RNA biology and therapy.
Suzanne M. McDermott +18 more
wiley +1 more source
Equine trypanosomiasis, a systematic review and meta‐analyses: Prevalence, morbidity and mortality
Equine Veterinary Journal, Volume 58, Issue 2, Page 291-319, March 2026.Abstract Background Equine trypanosomiasis is a neglected protozoal disease. Objectives To perform a systematic search of literature to explore: (1) In equines what is the global geographical distribution and prevalence of trypanosomiasis? In low and middle‐income countries (LMICs) is trypanosomiasis more prevalent than in higher‐income countries (HICs)
Alexandra G. Raftery +5 more
wiley +1 more source
Mechanical transmission of Trypanosoma congolense in cattle by the African tabanid Atylotus agrestis
, 2003 The trypanosomes pathogenic to livestock in Africa (Trypanosoma congolense, Trypanosoma vivax, and Trypanosoma brucei) are mainly cyclically transmitted by tsetse (Glossina). However, T.
Dia, Mamadou Lamine, Desquesnes, Marc
core +1 more source
Cytotoxicity and Antimicrobial Activity of GaMF1 Analogs
ChemMedChem, Volume 21, Issue 4, 25 February 2026.GaMF1 is a reported, highly potent inhibitor of mycobacterial ATP synthase. Structural modification of this scaffold significantly changes biological activity. We present GaMF1 analogues with strong antiparasitic effects, potential antiproliferative properties, and discuss the selectivity limitations of the parent compound and its analogues.
Jan Chasák +8 more
wiley +1 more source
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1976 Trois souches de Trypanosoma congolense ont été récoltées en 1964 dans le Sud-Ouest du Sénégal et l'une d'elles passée sur souris pendant plus de 10 ans. Les trois souches présentent la variation Dimorphon.
Saydil Touré
doaj +1 more source
The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa
The FEBS Journal, Volume 293, Issue 4, Page 948-958, February 2026.Metacaspases are Ca2+‐dependent cysteine proteases whose structural characteristics, particularly calcium binding and autocatalytic processing, govern their activation and biological functions. These enzymes differ among microorganisms and regulate their cell cycles, making them excellent targets for drug development.
Ane C. M. Duarte +9 more
wiley +1 more source