Results 61 to 70 of about 7,746 (218)

Equine trypanosomiasis, a systematic review and meta‐analyses: Prevalence, morbidity and mortality

Equine Veterinary Journal, Volume 58, Issue 2, Page 291-319, March 2026.
Abstract Background Equine trypanosomiasis is a neglected protozoal disease. Objectives To perform a systematic search of literature to explore: (1) In equines what is the global geographical distribution and prevalence of trypanosomiasis? In low and middle‐income countries (LMICs) is trypanosomiasis more prevalent than in higher‐income countries (HICs)
Alexandra G. Raftery, Lauren Gummery, Karelhia Garcia, Dinesh Mohite, Paul Capewell, David G. M. Sutton   +5 more
wiley   +1 more source

Immune Depression in Trypanosoma Congolense-Infected Mice

, 1979
The capacity of spleen cells from Trypanosoma congolense-infected mice to respond to the mitogens concanavalin A and bacterial lipopolysaccharide and to allogeneic lymphocytes is severely depressed or abolished. Moreover these cells cannot serve as stimulators of DNA synthesis in mixed lymphocyte reactions.
Roelants, G.E., Pearson, T.W., Mayor-Withey, K.S., Lundin, L.B.   +3 more
openaire   +3 more sources

Mechanisms Controlling Anaemia in Trypanosoma congolense Infected Mice

PLoS ONE, 2009
Trypanosoma congolense are extracellular protozoan parasites of the blood stream of artiodactyls and are one of the main constraints on cattle production in Africa. In cattle, anaemia is the key feature of disease and persists after parasitaemia has declined to low or undetectable levels, but treatment to clear the parasites usually resolves the ...
Noyes, H.A., Alimohammadian, M.H., Agaba, Morris, Brass, A., Fuchs, H., Gailus-Durner, V., Hulme, H., Iraqi, F.A., Kemp, Stephen J., Rathkolb, B., Wolf, E., Angelis, M.H. de, Roshandel, D., Naessens, Jan   +13 more
openaire   +7 more sources

Cytotoxicity and Antimicrobial Activity of GaMF1 Analogs

ChemMedChem, Volume 21, Issue 4, 25 February 2026.
GaMF1 is a reported, highly potent inhibitor of mycobacterial ATP synthase. Structural modification of this scaffold significantly changes biological activity. We present GaMF1 analogues with strong antiparasitic effects, potential antiproliferative properties, and discuss the selectivity limitations of the parent compound and its analogues.
Jan Chasák, Petr Vyvlečka, Ivan Nemec, An Matheeussen, Natascha Van Pelt, Paul Cos, Guy Caljon, Vladimír Kryštof, Lucie Brulíková   +8 more
wiley   +1 more source

Consistent detection of Trypanosoma brucei but not T. congolense DNA in faeces of experimentally infected cattle

Scientific Reports
Animal African trypanosomiasis (AAT) is a significant food security and economic burden in sub-Saharan Africa. Current AAT empirical and immunodiagnostic surveillance tools suffer from poor sensitivity and specificity, with blood sampling requiring ...
Isabel Saldanha, Martha Betson, Christina Vrettou, Edith Paxton, James Nixon, Peter Tennant, Adrian Ritchie, Keith R. Matthews, Liam J. Morrison, Stephen J. Torr, Lucas J. Cunningham   +10 more
doaj   +1 more source

Evaluation de la capacité vectorielle de Glossina tachinoides (Diptera, Glossinidae) vis à vis de Trypanosoma (Nannomonas) congolense : implications épidémiologiques [PDF]

, 1996
Cent quatre vingt-deux Glossina tachinoides ont été infectées avec Trypanosoma congolense type "savane". Les taux d'infection ont été évalués par examen microscopique et par PCR.
Cuisance, Dominique, Cuny, Gérard, Duvallet, Gérard, Frézil, Jean-Louis, Gidudu, A., Reifenberg, Jean-Marc   +5 more
core   +1 more source

The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa

The FEBS Journal, Volume 293, Issue 4, Page 948-958, February 2026.
Metacaspases are Ca2+‐dependent cysteine proteases whose structural characteristics, particularly calcium binding and autocatalytic processing, govern their activation and biological functions. These enzymes differ among microorganisms and regulate their cell cycles, making them excellent targets for drug development.
Ane C. M. Duarte, Mariana N. R. Trujilho, Karolaine S. S. M. Valdivia, Aline F. Araujo, Laura M. C. de Lorena, Vinicius H. de Oliveira, Beatriz V. Pereira, Emilly R. Leme, Wagner A. S. Júdice, Maurício F. M. Machado   +9 more
wiley   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, Volume 301, Issue 2, Page 280-329, February 2026.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Molecular identification of trypanosome species in trypanotolerant cattle from the south of Gabon

Parasite, 2017
The aim of this study was to provide information on trypanosome species infecting trypanotolerant cattle from southern Gabon. The study was conducted on 224 trypanotolerant cattle from three regions located in southern Gabon, using ITS1 primer-based PCR.
Maganga Gaël Darren, Mavoungou Jacques-François, N’dilimabaka Nadine, Moussadji Kinga Ivan Cyr, Mvé-Ondo Bertrand, Mombo Illich Manfred, Ngoubangoye Barthélémy, Cossic Brieuc, Mikala Okouyi Clency Sylde, Souza Alain, Leroy Eric Maurice, Kumulungui Brice, Ollomo Benjamin   +12 more
doaj   +1 more source

Seasonal Dynamics and Associated Risk Factors of Bovine Trypanosomosis and Its Vector in Selected Districts of Gamo and Gofa Zones, Southern Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
The median PCV of poor body‐conditioned animals is below 20 (anaemic) compared to corresponding body‐condition animals. Black‐ and red‐coloured animals are more significantly affected by trypanosomosis than white‐coloured animals. Multivariable logistic regression revealed more about contributory factors than univariable logistic regression.
Solomon Mekuria, Aschenaki Kalsa
wiley   +1 more source