Results 91 to 100 of about 155,237 (261)

Crystal structure of Kunitz-type trypsin inhibitor: Entomotoxic effect of native and encapsulated protein targeting gut trypsin of Tribolium castaneum Herbst

Computational and Structural Biotechnology Journal
Trypsin inhibitors are known to act against insect pests by inhibiting proteases of the digestive tract. In this study, we report structural and functional characterization of ∼ 19 kDa Albizia procera Kunitz-type trypsin inhibitor (ApKTI) protein with ...
Sohaib Mehmood, Soren Skou Thirup, Sarah Ahmed, Nabila Bashir, Ahsan Saeed, Maria Rafiq, Qamar Saeed, Muhammad Najam-ul-Haq, Binish Khaliq, Muhammad Ibrahim, Wadi Brak Alonazi, Ahmed Akrem   +11 more
doaj   +1 more source

Improving the understanding of plasma kallikrein contribution to arterial thrombus formation using two plant protease inhibitors

Platelets, 2019
The purpose of antithrombotic therapy is the prevention of thrombus formation and/or its extension with a minimum risk of bleeding. The inhibition of a variety of proteolytic processes, particularly those of the coagulation cascade, has been reported as ...
Bruno R Salu, Silvana Cristina Pando, Marlon V De Brito, André Fernando Medina, Frank Odei-Addo, Carminita Frost, Ryno Naude, Misako U Sampaio, Jonas Emsley, Francisco Humberto A. Maffei, Maria Luiza V Oliva   +10 more
doaj   +1 more source

Protease Inhibitors from Marine Venomous Animals and Their Counterparts in Terrestrial Venomous Animals

Marine Drugs, 2013
The Kunitz-type protease inhibitors are the best-characterized family of serine protease inhibitors, probably due to their abundance in several organisms.
Caroline B. F. Mourão, Elisabeth F. Schwartz   +1 more
doaj   +1 more source

Ultrasound-enhanced interfacial adsorption and inactivation of soy trypsin inhibitors. [PDF]

Ultrason Sonochem, 2023
Wu Y, Li W, Zhu H, Martin GJO, Ashokkumar M.   +4 more
europepmc   +1 more source

Bubble Formation Control: Fabrication of Centimeter‐Sized Tissue‐Like Constructs by Catalase‐Coated Oxygen‐Releasing Hydrogel

Advanced Materials, EarlyView.
Oxygen‐releasing hydrogels are widely used to support cell survival in 3D cultures and to promote wound healing. However, incorporating catalase to convert H2O2 into O2 often generates additional oxygen bubbles, leading to material instability which rarely addressed.
Sukulya Bunuasunthon, Isabel F. Amaral, Ana P. Pêgo, Michiya Matsusaki   +3 more
wiley   +1 more source

Antibacterial action mechanisms and mode of trypsin inhibitors: a systematic review. [PDF]

J Enzyme Inhib Med Chem, 2022
de Souza Nascimento AM, de Oliveira Segundo VH, Felipe Camelo Aguiar AJ, Piuvezam G, Souza Passos T, Florentino da Silva Chaves Damasceno KSFDS, de Araújo Morais AH.   +6 more
europepmc   +1 more source

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

Trypsin inhibitors in seeds and pods of Phaseolus vulgaris/coccineus: A comparative study of shaking and ultrasonic extraction methods

Electronic Journal of Biotechnology
Background: Different methods for the extraction of trypsin inhibitors in beans (Phaseolus spp.) were investigated. Two randomised complete laboratory experiments were performed, one on the seeds and one on the pods.
Hourieh Tavakoli Hasanaklou, Barbara Pipan, Vladimir Meglič, Nevena Nagl, Lovro Sinkovič   +4 more
doaj   +1 more source

Spiders' digestive system as a source of trypsin inhibitors: functional activity of a member of atracotoxin structural family. [PDF]

Sci Rep, 2023
Neto OBS, Valladão R, Coelho GR, Dias R, Pimenta DC, Lopes AR.   +5 more
europepmc   +1 more source

Sustainable Poly(Lactic Acid)/Graphene Oxide Bioelectronic Platform for Neurotransmitters Sensing and Tunable Stimulation of Astrocytes

Advanced Materials, EarlyView.
This work introduces sustainable PLA/graphene oxide bioelectronic interfaces featuring electrodes with tunable conductivity and strong electrocatalytic performance. These platforms were used to implement a new method for tuning astrocyte Ca2+ signaling and for the efficient detection of key biomarkers.
Alessandra Scidà, Giulia Cazzador, Roberta Fabbri, Matteo Calosi, Alessandro Silvestri, Andrea Candini, Fabiola Liscio, Franco Corticelli, Aikaterini Konstantoulaki, Andrea D'Iorio, Marco Caprini, Vincenzo Palermo, Monica Bertoldo, Valentina Benfenati, Chiara Zanardi, Emanuele Treossi   +15 more
wiley   +1 more source